UT Southwestern researchers discover role of two genes involved in cholesterol excretion
..."The disruption of the two genes, Abcg5 and Abcg8, reveals their crucial role in biliary cholesterol secretion," said Dr. Liqing Yu, an instructor in the Eugene McDermott Center for Human Growth and Development and in molecular genetics and lead author of the study. "In humans and mice, the secretion of chol...Council for Responsible Nutrition questions WAVE study conclusions
...ta." CRN noted that careful analysis of the study reveals the study showed no effects beyond random variations in response and that the researchers based their conclusions on statistically insignificant data. "In fact, the actual data showed no difference in artery blockage between the antioxidant group a...UC Berkeley scientists detail neural circuit that lets eye detect directional motion
...s visual information like our own eyes. "This work reveals a very sophisticated neural computation, the first non-linear computation performed by the nervous system for which a circuit is close to being solved," said Frank Werblin, professor of molecular and cell biology at UC Berkeley. "It is a preliminary ...Drug delivery leaps biotech hurdles
...(www.Technical-Insights.frost.com), Drug Delivery, reveals that over 300 companies are currently developing various avenues of drug delivery. Emerging technologies ranging from medicated powders pumped into the skin at supersonic speeds, to implanted microchips that deliver precise dosages, to nano-molecular...Researchers question authenticity of new malaria drug
A new investigation by The Scientist magazine reveals that some researchers believe the anti-malaria drug Malarex has not been adequately tested or, worse still, may be a fraud. The drug, touted by its Canadian manufacturer Millenia Hope as safe and effective, is already approved for sale by five Africa...UT Southwestern Nobelists find protein structure that may help fight high cholesterol
...eller" region. In the Science study, the structure reveals that parts of the LDL binding region attach to the "beta-propeller" region at low pH and thus cannot bind to LDL. It looks as if the "beta-propeller" region competes with LDL, Deisenhofer said. "The LDL receptor is crucial to clearance of LDL and in ...Scientists discover gene 'signature' for tumor's tendency to spread
... By contrast, the researchers say their discovery reveals that the tumor is "encoded" with metastatic potential from early on by a certain group of genes, and that this same group is found in a variety of tumor types. Ramaswamy and his colleagues compared genetic patterns in samples of primary tumors and s...Got milk? Scientists discover key lactation gene
... previously unidentified role for XOR in lactation reveals a possible genetic basis for the lactation difficulties experienced by nearly 5% of women. XOR was originally identified as encoding an enzyme involved in purine catabolism (the breakdown of adenine and guanine nucleotide bases). Because XOR is expre...Scientists find fully differentiated blood cells remain able to switch identity
... journal's print edition in March 2003. "This work reveals that seemingly committed cells have more plasticity than we had thought," said senior author Andrei Thomas-Tikhonenko, assistant professor of pathobiology at Penn. "It appears there is at least a small window where terminally differentiated cells va...A new study sheds light on how the tongue restores its ability to taste following surgery
...s" exist for the regenerated nerve. This research reveals that effects of CT cut and sodium restriction on sodium taste function in the two sides of the tongue are likely to be due to different mechanisms. The intact CT is susceptible to sodium restriction in the first week after sectioning, while the regen...January GEOLOGY and GSA TODAY media highlights
...lona, Spain, et al. Pages 83-86. Submarine mapping reveals the surficial expression of several fault structures <100 km offshore Portugal (SW Iberian Margin), at the boundary between the European and African plates. High-resolution seismic data show folding and reverse faulting of the Quaternary units as...Invariant properties in coevolutionary networks of plant-animal interactions
...rks, the internet, airport connections, etc. This reveals for the first time a generalized topology characteristic of self-organized complex systems and has important implications for the conservation of biodiversity....UF study: Calorie restriction reduces age-related brain cell death
...discovery is valid, he said, "the authors' finding reveals a novel aging pathway that could be targeted by other dietary manipulations or drugs."...UCI study offers blueprint for pinpointing sources of beach water pollution
...e of Environmental Science & Technology. The study reveals that it's possible to identify and track the specific sources of water pollution by combining bacteria sampling with genetic testing. The research team used this technique while studying the causes of beach pollution in Avalon, Catalina Island -- a p...Scientists hone in on cause of amphibian deformities
... researchers, the story of the parasitic trematode reveals just how complicated natural ecological processes can be, and how difficult it is to trace problems to their underlying cause. In its life cycle, the parasite at times depends on snails for survival and birds for reproduction and transportation. The ......sis. This finding by Dr. Greenstein and colleagues reveals an unexpected role for VAB-1 in reproduction. C. elegans worms are facultative hermaphrodites, meaning that the species has both males and hermaphrodites, and is therefore capable of self- or cross-fertilization. In C. elegans, developing ooctyes tra...Researchers decipher cause of parasites worldwide spread
...hington University School of Medicine in St. Louis reveals that a unique combination of genes inherited less ...lop over long periods with their hosts. This study reveals that parasites sometimes adapt rapidly to new hosts, indicating that host-parasite relationships may...JCI table of contents, January 15 2003
...79.pdf Decreased atherosclerosis in CX3CR1/ mice reveals a role for fractalkinein atherogenesis CONTACT: Israel Charo Gladstone Institutes of Cardiovascular Disease P.O. Box 419100 San Francisco, CA 94141-9100 USA Phone 1: (415) 826-7500 Fax 1: 415-285-5632 E-mail: icharo@gladstone.ucsf.edu View the PDF...Prehistoric NW Indians hunted fur seals of sustainable basis
...University of Washington last month. His work also reveals evidence of previously unknown rookeries, or breeding colonies, of the seals (Callorhinus ursinus) on or near the Washington coast and on or near the Alaskan Peninsula. The findings come from his not-yet-published doctoral dissertation. Etnier's res...Effects of rare, devastating disease linked to shrinking of cells' telomeres
...eature of the AT condition in humans. "This study reveals the complexity of the genetic interactions between Atm deficiency and telomere dysfunction" in living mice, the authors wrote....