Structural mechanism of cell enzyme revealed by UT Southwestern researchers
...published in the June issue of Molecular Cell. It reveals how the mitogen-activating protein (MAP) kinase enzyme p38 maintains fidelity along its cell-signaling pathway. Scientists previously believed that mammalian enzymes contained only one binding site (a place on a protein that recognizes another protei...Ocean aquaculture: Technology, business practices, policies & caviar
...2, Email: chris.bridger@usm.edu Economic study reveals risks of ocean aquaculture business operations Aquaculture is a business, and good business requires a plan. In order to develop a plan for open ocean aquaculture operations, WHOI policy analysts developed an economic model to explore the feasibil...Men die young, even when they're old
... for your health. A new study across 20 countries reveals for the first time just how much bigger the risk of premature death is for men than women, whatever their age. In the US in 1998, for example, men up to the age of 50 were on average twice as likely as women to keel over, and the risk remained greate...Bioinformatics: The quest for new drugs finds significant profits
...www.technical-insights.frost.com), Bioinformatics, reveals that three fields will be most affected by advances in bioinformatics, all with the goal of structure-based drug design: genomics, proteomics, and combinatorial chemistry. The report also profiles representative key companies and academic groups, and...Dartmouth researchers identify multi-tasking circadian protein
...ever, this finding with the White Collar-1 protein reveals a relatively simple process between a light-perceiving protein and turning on a gene. "Virtually nothing is known about how pathogenic fungi respond to light or whether our discovery can be exploited for a noninvasive medical therapy," Dunlap says. "...Scientist says ostrich study confirms bird 'hands' unlike those of dinosaurs
...appear similar, but close and detailed examination reveals many differences, Feduccia said. Theropod dinosaurs, for example, had curved, serrated teeth, but the earliest birds had straight, unserrated peg-like teeth. They also had a different method of tooth implantation and replacement. Findings from caref...Convergent technologies: Is your company ready for the future?
...vations. Further, the annual survey by Inside R&D reveals that the top 100 U.S. companies have spent more than $124 billion on R&D in 2001, up 16.2 percent from the previous year. Companies in the pharmaceuticals, automotive, and telecommunications sectors have made the largest investments. "Business and in...... being made by Dr James Nazroo, whose new research reveals that victims of racist verbal abuse are 60 per cent more likely to suffer from poor health, and those whose property is subjected to vandalism are twice as likely to report fair or poor health. Dr. Nazroo is based at the Department of Epidemiology a...Structure reveals details of cells cargo-carriers
... structure produced by Goldberg and his colleagues reveals how the change in Sar1's shape enables Sec23/24 to...tely assume. According to Schekman, "the structure reveals the mechanism by which the complex anchors to the ER membrane and how its curvature might impart cur......epresentation, called a "contact map." The 2-D map reveals the chemical and other interactions among amino acids--data that are difficult to extract from the more complex 3-D images. The data are mined from the contact map is then transferred into a knowledge bank of "contact rules" and used to predict un...Pesticide resistance warning after gene discovery
..., even to those the species has never encountered, reveals new risks and costs to the chemical control of pest insects. Unless we reassess our current methods of pest management, our future options for control may become severely restricted," he says. "If this mutation was found on a pest insect, many opti...JCI table of contents: October 1, 2002
...er at the University of California, San Francisco, reveals that mice lacking a form of the enzyme protein kinase C (PKCe) are supersensitive to their brain's own calming neurosteroids and exhibit reduced anxiety. The authors suggest that inhibitors of PKCe may be useful in treating anxiety. Severe and excess...Relaxed mice may provide clues for treating anxiety
...er at the University of California, San Francisco, reveals that mice lacking a form of the enzyme protein kinase C (PKCe) are supersensitive to their brain's own calming neurosteroids and exhibit reduced anxiety. The authors suggest that inhibitors of PKCe may be useful in treating anxiety. Severe and excess...Smart materials expand within global marketplace
...w.Technical-Insights.frost.com ), Smart Materials, reveals developments in SMAs, SMPs, electrochromic materials and fullerenes, while profiling R&D efforts at more than two-dozen organizations and reviewing companies that have smart material-based products on the market or in development. Smart Materials als...New guide helps researchers mine genome data
...e with accession number AF288398. The e-PCR search reveals the sample sequence contains only one STS, stSG47693. By clicking on the marker name, users can obtain more details about the STS from UniSTS, such as alternative names for the marker, primer information and PCR product size. In addition, the NHGRI ...New map shows human 'footprint' covers most of the Earth
...ion such as urbanization and agricultural use. It reveals that 83 percent of the land's surface is under human influence, while a staggering 98 percent of the area where it is possible to grow rice, wheat or maize is directly influenced by human beings. At the same time, wide swaths of land still remain wi...New nanoparticle coating mimics dolphin skin
...eterogeneous coating that, upon close examination, reveals treacherous nano-sized terrain composed of mountains and valleys, ranging from hard to soft, hydrophilic to hydrophobic. Getting a feel for the terrain So how does such a coating minimize macroscopic fouling? The key is the complex surface, which...Molecular imaging: diagnosing diseases before symptoms strike
...lls are growing at a faster rate. PET-scan imaging reveals this higher level of uptake, thereby providing a non-surgical means of detecting an otherwise hidden tumor. Researchers at Washington University's Molecular Imaging Center are developing new applications for existing technologies, such as PET, and e...UT Southwestern scientists discover link between infections in mothers and brain injuries in babies
...ut we still don't have all the answers." The study reveals the link between brain injury that occurs during the perinatal period - immediately before and after birth - and an infection in the mother's placenta, called chorioamnionitis, which causes fever, inflammation, and abnormally high heart rates in the ...... the fiber assembly process. X-ray crystallography reveals the 3-D arrangement of atoms in proteins. UTIs are the second most common infectious disease in the United States, says Hultgren. Each year they account for 100,000 hospital admissions and 8 million doctor visits. UTIs mainly affect women, about hal...