Progress in breast cancer progression
...nsition had already occurred caused these cells to revert back to their original state. To test this in a living model, the authors blocked the NF-kB pathway in nude mice that were injected with breast cancer cells. Under these conditions, these breast cancer cells were unable become metastatic, unlike th...JCI table of contents, 16 August, 2004
...nsition had already occurred caused these cells to revert back to their original state. To test this in a living model, the authors blocked the NF-kB pathway in nude mice that were injected with breast cancer cells. Under these conditions, these breast cancer cells were unable become metastatic, unlike tho...Stem cells toward sperm cells and back again
...ew types of fairly specialized cells can naturally revert to their stem cell origins at times -- think regro... not more -- away from their stem cell origins can revert to the more primitive state. Understanding how and until what point specialized cells can reverse c...Malignant breast cancer cells to revert to normal with manipulation
...ronment can allow malignant breast cancer cells to revert to normal cells again. She also describes how the tissue culture of the extracellular matrix affects the cancerous cells' resistance to chemotherapy, independently of the characteristics of the malignancy itself. Her presentation is part of the scien...Can a plant that acts like poison ivy cure prostate cancer?
... effect on myeloid leukemia cells, causing them to revert to normal cell behavior," Conney explained. However, it was a long time before anyone acknowledged that TPA could actually do good things for people, Conney observed. Investigators at China's Henan Tumor Research Institute an...Tissue cells can revert to stem cells
...g development in the fruitfly can be stimulated to revert to fully functioning stem cells. "This finding cou...he larval ovary may have helped cause the cells to revert back to stem cells," Kai commented. "First, the larval ovary has an abundant supply of the fruitfly...Mice cloned from olfactory cells
... an egg, or oocyte, depleted of its nucleus, could revert to an undifferentiated state in which it could give rise to an adult mouse possessing the full range of olfactory receptors.Indeed, the resulting mice exhibited an array of well-organized odorant receptors that were indistinguishable from those of no...A big surprise: Young nerve cells can rewind their developmental clocks
...is inactivated or turned off, the program seems to revert to its earliest stage. The researchers do not know how late in the game they can play their genetic tricks. If they turn off the Foxg1 gene at a later time in development, such as when cortical layers 2 or 3 are forming, will progenitor neuron...Purdue researchers solve decades-old corn, sorghum problem
... that causes dwarf sorghum plants to spontaneously revert to a taller form. In corn, the normal gene Br2 pro...on, Johal said it is a stable mutant that will not revert back to a tall form. "This single discovery of a stable mutant will have an immediate impact on sorg......with mice, the Max Planck researchers were able to revert the observed age-related learning and memory deficits by down-regulation of calcium-activated potassium channels (SK3) located in the hippocampus, a brain region recognized to be important for learning and memory. The researchers published their resu...ORNL researchers expect big things from nanostructures
...e access to the modifying DNA and therefore should revert to their normal genetic makeup, McKnight said. In addition to investigating nanofiber platforms for DNA delivery, the group is involved in a $1.7 million three-year effort to apply nanofiber devices for high-resolution molecular imaging of cells and ...Multiple lifestyle changes effectively lower blood pressure
...elping people maintain these changes so they don't revert back to less healthy behaviors." The group that had the best outcomes received counseling on the Dietary Approaches to Stop Hypertension (DASH) diet, which emphasizes fruits, vegetables and low-fat dairy products. It includes whole grains, poultry,...Virginia Tech inventions, creations can improve lives
...elatively safe to handle and manufacture, does not revert to a pathogen or mutate, and does not retain resistance to antibiotics used in the treatment of brucellosis. The patent also provides methods for diagnosis of Brucellae infection, a diagnostic kit for use in detecting the presence of Brucellae in mam...Cancer squeezes through the gaps
...planation for this failure: the drug-treated cells revert to a primordial, ameboid form of cell movement that allows them to squeeze through gaps in the matrix. Peter Friedl (University of Wuerzburg, Germany) and colleagues report in the January 20 issue of The Journal of Cell Biology that cancer cells mo...Transposable elements in malaria mosquito genome may offer a tool for control of disease spread
...n mutated, the mutated stock would later appear to revert at high frequency. "She had discovered that the mutation and reversion was caused by segments of the DNA moving in and out of a genetic locus in the genome," says Tu. "Until then, we thought of the genome as static." Now researchers know that portion...Cause of hepatitis A virulence pinpointed
...covered that deliberately weakened HAV can quickly revert to its naturally occurring, infection-causing form. To be published in the September 1 issue of Journal of Virology, and appearing online this week, these findings indicate that making an improved vaccine for HAV will be a very difficult task. "A...Clonal human (hNT) neurons re-establish connection in rats with severe spinal cord injury
...and humans has shown that these hNT neurons do not revert to cancer cells. The USF team studied three groups of rats with severe SCI. One group was administered hNT neurons immediately following injury, another received transplants two weeks after SCI injury, and the third, a control group, received no tr...Lack of Rb2 gene could be early indicator of prostate cancer, say Temple researchers
... we could reintroduce the Rb2 gene and potentially revert the situation back to normal by blocking the growth of the neoplastic cells that will eventually become cancer." The study, which was led by Giordano and Dr. Pier Paolo Claudio, associate professor of biology at Temple and a member of the Sbarro Ins......y dont die, but they quit working and may actually revert to an immature embryonic-like state, says Stuart Dryer, a neuroscientist in the department of biology and biochemistry at UH. Embryonic nerve cells are able to fire electrical impulses shortly after the cells have divided for the last time after th......e implication of this finding is that cancers that revert to earlier stages of development may be using this...suggests that the cancer uses this modification to revert back to an earlier stage of development, to spend all its time utilizing genes that allow mainly for...