Genetically-engineered 'marathon mouse' keeps on running
...t this experiment is that this one change seems to rewire the entire system. "That's exciting to us because it says that this complicated system can be coordinately changed by changing just one part. It also shows that it can be changed genetically, without exercise itself. This means that activation of th...Leptin rewires the brain's feeding circuits
... of studies revealed that leptin acted directly to rewire the neuronal feeding circuitry itself in the brains of mice, specifically suppressing NPY neurons and exciting POMC neurons. The researchers also found that administering leptin to the leptin-deficient ob/ob mice produced changes in neuronal connec...Researchers reveal new secrets of the brain
... convincing proof to date that the adult brain can rewire itself in response to outside world. While many neuroscientists had begun to speculate that adult brains might be more dynamic than once thought, neuroscience orthodoxy still held that adult brains are relatively stable, limiting learning and recover...New insight into how eyes become wired to the brain discovered by Salk, UT Southwestern scientists
...eed to be recapitulated following neural injury to rewire the nervous system," Henkemeyer said. "We plan to continue our collaborative effort and investigate these molecules and the mapping process further and hopefully come closer to completing the puzzle."...Injured spinal neurons reach out to each other, but not to healthy neighbors
...an important part of future therapeutic efforts to rewire neurons and their targets after injury. "Our study shows that neurons establish connection with other neurons after injury by creating bridges called gap junctions," says Rita J. Balice-Gordon, PhD, an assistant professor of neuroscience and senior a...Life Among Dead Brain Cells: Discovery Could Help Improve Memory Capacity Of Stroke Victims
...e stimulated to grow even more, perhaps helping to rewire the brain andhelp stroke survivors recover lost memory function. Stem cells are important in the formative stages of brain development. Researchers say stem cells help form neurons, which mature and make the complexcircuits that enable the br......ake things better," Orr says. "But ifyou go in and rewire everything and make a bunch of majorchanges, the chances aren't good that it'll have a positiveeffect." However, researchers began poking holes in that argument in1983, and now Orr has turned it on its head by showing that thedistribution of mut......arette. "Theybehave like a switchboard, so you can rewire around the damage." To test OP-1 in rats after artificially-induced strokes, Charette andhis colleagues from Massachusetts General Hospital and Harvard Medical Schoolinjected it into the cisterna magna, a brain cavity containing cerebral flu...