Protein vaccine fully protects mice from lethal aerosol challenge with ricin toxin
...r oil. When inhaled as a small-particle aerosol, ricin produces severe respiratory symptoms followed by r...espiratory failure within 72 hours. When ingested, ricin can cause severe gastrointestinal symptoms followed by vascular collapse and death. Given its r...Nanosphere announces genetic detection advance in Nature Biotechnology
... to test for hazardous biological toxins including ricin and botulinium toxin....Topical vaccine protects against inhaled ricin
...ine or specific therapy is currently available for ricin poisoning," says Gary Matyas of the Walter Reed Ar...esearchers incorporated a harmless fragment of the ricin molecule (RTA 1-33/44-198) into a transcutaneous immunization (TCI) formulation. TCI is a needle-fr...US crackdown on bioterror backfiring
...d to be quoted, had to drop a proposal for work on ricin because it required a collaborator with particular equipment. "None would work on a select agent without millions of dollars of government money, prepaid," the researcher says. On top of the financial burden, potential partners do not want to risk c...UT Southwestern researchers receive $15.1 million in federal grants to study biothreats
... of four investigators in developing a vaccine for ricin and for initiating clinical trials. Dr. Vitetta an...expects to initiate tests in mice against airborne ricin as early as the first quarter of 2004, when UT Southwestern is slated to complete a planned biosafet...New UNC emergency room wall chart will help health workers respond to chemical terrorism
...esicants/blister agents, pulmonary/choking agents, ricin and T-2 mycotoxins." A copy of the poster will be sent free to every North Carolina hospital because the staffs there do not have time to search for such guidance in an emergency. Information about purchasing additional copies will be available at w...UT Southwestern researchers develop vaccine against deadly bioterrorism toxin ricin
...issue of the journal Vaccine. Large stockpiles of ricin have been found in several countries in the Middle...It is a protein produced by castor beans. A single ricin molecule inside a cell shuts down protein synthesis, killing the cell. Ricin can be administered in ...Cellular Engineers Design Custom Cell Surfaces Able To Adhere To Synthetic Materials
... a derivative of thenatural plant toxin ricin. The ricin analog, synthetically armed with thereactive hydrazide group, sought out and reacted with the ketone-labeled cells. "It worked," says Bertozzi. "We killed 'em." Bertozzi's group is currently moving studies of hydrazide-labeled toxin...