Transposable Elements May Have Had A Major Role In The Evolution Of Higher Organisms
...ed that transposable elements were simplypieces of rogue DNA, barnstorming through the cellular world like petulantchildren, causing the misexpression of other genes and, in general, looking outfor number one. That early picture, however, began to change dramatically in the1970s, when it became clear that ...... might startpointing fingers," he says. What about rogue nations that might interfere with doctors' abilities to shareepidemiological information over the Internet? Nations that agree to terms of atreaty are entering into a cooperative agreement. If a participant nation beginscensoring doctors, you know so...A Synthetic Peptide Destroys Brain Plaque Implicated in Alzheimer's Disease
... to prevent amyloid formationby custom-designing a rogue peptide that mimicked the region of the amyloidpro...ids unable to adoptthe pleated form. They call the rogue a "beta-sheet breaker." "We believe that in order for amyloid to be formed, the protein has toa......ypesof cells arranged in the proper places, or the rogue travels of metastaticcancer cells. Van Vactor started this research as a postdoctoral fellow in the lab ofCorey Goodman at the University of California, Berkeley, who is a co-author onthe first paper. Using the fruit fly, Van Vactor ...Biological warfare: an emerging threat in the 21st century
...he governments of the United States and Russia. If rogue politicians or terrorists were to get hold of the remaining supplies, ``the consequences could be disastrous,`` he warns. But Block is haunted by more than the threat of a smallpox attack. He points to some two dozen conventional biological agents -...Scientists discover a genetic cause for severe complication of the autoimmune disease lupus
... immune system's normal ability to rid the body of rogue antibodies. When the immune army is not appropriately held in check, it may start attacking the body's own cells and tissues, causing rampant inflammation and other ailments. The new research examined naturally occurring variants of two genes for...Unleashing GMO's into the environment
...University in Indiana have developed a way to spot rogue GM organisms long before they are released into the environment. The technique could do for GMOs what clinical trials do for drugs. "Pharmaceuticals companies have to ensure that their drugs are safe for human consumption," says Muir. "Agricultu...The biological and toxin weapons convention an analysis
...m guidelines on biological weapons could result in rogue states developing new biological weapons. Dando and Whitby identify several areas of biological research that could be exploited to be used as weapons, these include: the production of venom toxins in genetically modified bacteria, creating antibioti...Terrorist threats to agriculture studied
...h work to do. "We are concerned not with just the rogue nations, but with any individual who may be disgruntled and wish to carry out an act of bioterrorism," Clarke said. And he noted that such research also would be useful in the event of an accidental outbreak of some pestilence that threatens the food......g ZD1839 (Iressa), act synergistically against two rogue genes commonly involved in breast cancer. The result was that while each agent blocked the growth of a proportion of breast cancer cells expressing these genes, combining the two was even more effective. "I would stress that this approach is still hi...UK researchers shed new light on a cause of recurrent miscarriages
...with a normal copy of the gene. For women with the rogue gene who had a history of late miscarriage only one out of nine had a live birth compared with 22 out of 45 of the women with the normal gene. The research was carried out by teams from the Department of Reproductive Sciences, Imperial College of Sci...Researchers identify protein that regulates killer cells
... develop treatments and therapies to counter these rogue cells," says Binns. A group of genes called the major histocompatibility complex I (MHC-I) are a natural part of the immune system and present in most cells in the body, explains Binns. Acting like an information relay, the MHC-I molecules retrieve b...Pinpointing the mutations that cause resistance to Gleevec
...esearchers have identified specific mutations in a rogue gene that render the drug Gleevec ineffective in patients who have chronic myeloid leukemia. The studies could provide new information that may improve the effectiveness of second-generation drugs for chronic myeloid leukemia (CML). The researchers s...Imaging apparatus characterizes drops in 'dirty' laboratory environments
...y partial vaporization. To investigate the role of rogue drops in this process, Scheeline and hiscolleagues -- Illinois postdoctoral researcher Jerry Cabalo, Arizona professor and head of chemical and environmental engineering Jost Wendt, and Arizona graduate student John Schmidt -- developed an optical sy...Biosensor research expands globally to reach a variety of key industries
... that are the deadliest weapons in terrorism's and rogue states' arsenals," says Technical Insights Analyst Michael Valenti. Because biosensors are costly devices, many companies and universities, and their researchers are seeking ways to make them more economical. For example, molecular imprinted polymers...Six reporters named to receive 2002 AAAS Science Journalism Awards
...knowledge--from forensics to the identification of rogue bears, and from genetic fingerprinting of threatened creatures to the development of pollutant-degrading microbes. Online Alan Boyle of MSNBC.com earned the AAAS prize for online entries, with an article titled, "Genetic Genealogy: How science i...First potentially clinically useful independent marker for lung cancer identified
...the damage would multiply, resulting in a group of rogue cells the start of cancer. ERCC1's downside is ... If ERCC1 levels are low, there is less chance the rogue cells will be repaired. "So ERCCI is truly a doubled-edged sword. In early cancers or cancers where ...Mouse genetic model for spongiform brain diseases
...thies like mad cow disease, Gunn believes, because rogue prions are not the cause of the mouse condition. But as an example of defective ubiquitination -- a protein-related process involved in many neurodegenerative disorders, including Parkinson's and Alzheimer's diseases -- the mahogany-colored mice with...Researchers discover possible diagnosis, treatment, vaccine for mad cow, prion diseases
...roteins that have been compromised and folded into rogue shapes. "The usual way of raising antibodies in the immune system is to grind the infectious agent up and inject it into a mouse to see if it prompts antibody production," he says. "Scientists have tried this method with prions over the past 15 years...Distinctive genetic program guides breast cancer's deadly spread
...de breast cancer's toolbox and identified a set of rogue genes that accelerates the spread of cancer from its primary site in the breast to a secondary location in bone marrow. The genes identified by the scientists are distinct from those that spawn the initial tumor, which invites speculation about wheth...