Disease diagnosis, drug development focus of UH prof's biochip research
...ntal and theoretical nanosciences, to showcase the role of computational science underpinning and enabling innovations, and to consider specific applications of nanotechnology. Conference proceedings will be published in the international journal, Molecular Simulation....Purdue study finds antioxidant protects metal-eating plants
...iquitous antioxidant, glutathione plays a critical role in minimizing oxidative stress, or damage caused b... to establish that glutathione played a functional role in nickel tolerance. He and his colleagues isolated a gene called SAT, and inserted it into a model...JCI table of contents: 1 September, 2004
... TITLE: Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of...te of primary immune cell activation plays a major role in determining the balance between tolerance and immunity. This may have important implications for ...Analysis of gene expression in lymphoid cells can determine lymphoma cancer
...een discovered, one of the most interesting is the role of this kinase in cellular differentiation, particularly muscle differentiation."In practical terms, when we overexpress this protein, we are able to promote myogenic differentiation by enhancing the myoD function," says Giordano, who also discovered...Scientists discover proteins involved in spread of HIV-1 infection
... the newly identified VPS37 proteins play a direct role in HIV budding. In principle, the VPS37 proteins are therefore potential new drug targets, though of course many significant hurdles remain to be overcome, such as inhibitor screening and potential problems with cellular toxicity."...NHGRI launches Centers for Excellence in Ethical, Legal, and Social Implications Research
...a team to gather and analyze information about the role of publication, data and materials sharing, patenting, database protection and other practices that may affect the flow of information in genomics research. Research pertaining to these topics will make a much-needed contribution to the understanding...Protein involved in childhood disorder linked to cancer
...in a congenital neurological disorder also plays a role in DNA damage repair and thus cancer prevention. The research appears as the "Paper of the Week" in the August 13 issue of the Journal of Biological Chemistry, an American Society for Biochemistry and Molecular Biology journal. Primary microcepha...Green tea research leads to gum and other products
... and salivary gland cells, suggesting a protective role of EGCG in normal cells." Some methods of bolstering ROS are inadvertent; for instance, excessive sun exposure can increase ROS to the point of irreversible cell damage. Chronic exposure to carcinogens and certain drugs also can damage salivary gland...Mouse study shows NPAS3 and NPAS1 genes may be linked to psychosis
...ngst themselves and act as the brain's wiring. The role of inhibitory interneurons, on the other hand, is to dampen the activity of excitatory neurons. The NPAS1 and NPAS3 proteins are transcription factors that can activate or deactivate other genes. Just which genes they may control is unclear, Dr. ...APS awards more than $140,000 to minority students of physiology
... research is epidermal growth factor (EGF) and its role in protecting the intestine against a disease that...protein kinase C- (PKC-) and PKC- play an integral role in apoptosis through their interaction with hepatitis B X (HBx), a viral transactivator expressed du...Probing the surface of white blood cells to enhance immune system medicine
...ne system function, yet efforts to influence their role in illness have been hampered due to a lack of und... Research indicates that microvilli may play a key role in this process. They allow white blood cells hurtling through the bloodstream at speeds analogous t...MIT team explains yin-yang of ginseng
...al behavior of this drug and its structure." MIT's role in the collaboration grew from Sasisekharan's expertise in complex sugars, which turn out to be key to ginseng's activity. "The sites where sugars are attached and how they are attached are unique for each of the molecular constituents, the ratio of ...Advances in tumor angiogenesis Dendritic cells co-opted to the dark side
...treatments for it. "Dendritic cells play a central role in the generation of antitumor immune response," says Coukos. "As a result, it was believed that these were mostly good players in inducing tumor rejection." But when dendritic cells are part of the tumor microenvironment, instead of stimulating an i...Better living through urban ecology
...ting natural resource sustainability, the critical role of BES research cannot be overstated." People are a major component of urban ecology and BES works to forge strong bonds with Baltimore residents, leaders and governmental agencies. Renewed funding will aid outreach and enrich education programs gear...New tool predicts how long pollutants will stay in soil
...en Nguyen, a graduate student who played a leading role in adapting the math tool and demonstrating its effectiveness. "For many years, we've made predictions with a method that doesn't work very well on many chemical pollutants in soil. This new tool does a much better job." Nguyen, who is working toward...Streptococcus infects humans by thwarting blood clotting
...ing the protein, fibrin. A major question was what role streptokinase played in the bacterium's overall pathogenicity, said Ginsburg. To develop the "humanized" mouse that would be vulnerable to bacterial streptokinase, Sun attached the gene for human plasminogen to a regulatory DNA sequence that normally...New genetic research demonstrates possible cause of inherited form of Parkinson's disease
...kup at the protein disposal sites also plays a key role in the most common idiopathic form of Parkinson's, which has no known cause. "These patients do not carry a mutant alpha-synuclein gene, but their alpha-synuclein proteins bear modifications not seen in healthy people that may cause the protein to...Review article makes case for a new source of cells in the body
...stions such as the origin of VENT cells, the exact role they play in target tissues and if they are the so... Institutes of Health grant to further explore the role of VENT cells in craniofacial development and the genes that distinguish VENT cells from others. To ...OHSU-VAMC study sheds light on estrogen's benefit for MS
... well. Scientists have long been interested in the role sex hormones play in the body's ability to fight autoimmune diseases like MS, particularly since these disorders occur more frequently in females than in males. But the link between pregnancy and MS has been hotly debated. In 1998, scientists in Fran...Unicellular organisms contribute more nitrogen to ocean that reported earlier
...on or some other environmental factor is playing a role in determining the abundance, distribution and act...e ocean is significant, appears to play a critical role in driving the movement of elements through the ocean both in the upper layer of the water and from ...