UT Southwestern receives $1.78 million grant for obesity research as part of NIH Roadmap initiative
...s is the brain and liver, as these organs play key roles in the development of obesity and related disorders. Four research teams will concentrate on three objectives: to foster interdisciplinary interactions at UT Southwestern to study obesity and metabolic syndromes; to develop state-of-the-art research ...Newly identified master gene key in baby's first breath
.... While other genes have been identified as having roles in lung development, this master gene, called Foxa2, controls key factors that allow the lungs of a fetus to develop fully and eventually breathe air. While Foxa2 was previously known to exist, its role in lung maturation and function at birth were n...Posters highlight water, energy and other natural resource research
...d for the U.S. Department of Energy (DOE). INRA's roles in this contract include the support of collaborative basic and applied research programs between its member universities and the INEEL staff by funding several diverse multi-year research projects in the critical mission areas of the Laboratory, inc...NSF awards 22 new projects for plant genome research
... of relationships between genes and the biological roles they play; and databases and tools to capture, share and analyze the massive amounts of genomics data being produced by the scientific community. In addition, all projects continue the commitment of the PGRP to train the next generation of scientists...Information system to help scientists analyze mechanisms of social behavior
...at Illinois, is one of six scientists with leading roles in BeeSpace. Robinson also is coordinating the ho...ll generate a molecular signature of all the major roles performed by honey bees. "To do this," he said, "we will generate profiles of gene expression that ...JCI table of contents September 15, 2004
...ed in individuals with atheroscle-rosis, but their roles in the initiation and development of atherosclerosis remain ill-defined. To investigate the role of each of these prostanoids in atherosclerosis, Shuh Narumiya and colleagues, of Kyoto University Faculty of Medicine, have bred an ath-erosclerotic mou...Picking prostanoids to provide protection
...ed in individuals with atheroscle-rosis, but their roles in the initiation and development of atherosclerosis remain ill-defined. To investigate the role of each of these prostanoids in atherosclerosis, Shuh Narumiya and colleagues, of Kyoto University Faculty of Medicine, have bred an ath-erosclerotic mou...Spontaneous mutation produces new MAO A/B knockout mouse
...n excellent model in which to address the specific roles of these neurotransmitters and their receptors in ...actions of MAO A and MAO B, as well as examine the roles of neurotransmitters in anxiety- and stress-related disorders....Breaking new ground in germ cell guidance
... , have been known for some time to play important roles in the guidance of Drosophila pole cell migration by somatic cells. The genes encode lipid phosphate phosphatases (LPPs), which it had been proposed degrade an extracellular substrate, thereby creating an environment unfavorable to germ cells and ste...Virginia Tech researchers to release findings on Smith River Project
...f aquatic invertebrate forage; and identifying the roles that the tributaries play in defining the main channel community. The Smith River Research Project principal investigators are Virginia Tech fisheries professors, Don Orth, Tammy Newcomb, Andy Dolloff, civil and environmental engineering professo...Probing the surface of white blood cells to enhance immune system medicine
..., a type of white blood cell that have a number of roles in the immune system, including the production of antibodies and other substances that fight infection and disease. An essential feature of lymphocytes' ability to mount an immune response is their ability to migrate from the blood into infected tis...Circadian clock genes reign in duration of fruit fly copulation
...species including humans. Both genes play critical roles in the control of the 24-hour clock. However, despite their roles in controlling the timing of daily behaviors such as sleep, the period and timeless genes appear to ...PCB breakdown in rivers depends on sediment-specific bacteria, find Carnegie Mellon U. scientists
...se River sediment. "Our goal is to determine the roles that different bacterial populations play in PCB breakdown by identifying the kinds of microbes in river sediments as well as their population size and how they remove chlorine atoms from the PCB structure," said William Brown, Ph.D., professor of bi...When is a mouse like a test tube?
... cells decorate themselves. Such sugars play major roles in cell-cell interactions, and often provide entre to bacteria and viruses that cause disease. More than five years ago, she conceived of the idea of instigating reactions in the body between unnatural chemicals - ones created by humans and never bef...JCI table of contents, 16 August, 2004
... Bone Differentiation Gets NFAT TITLE: Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation AUTHOR CONTACT: Riko Nishimura Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka 565-0871, Japan Phone: 81-6-6879-2887; Fax: 8...Rare mutations can significantly increase risk factor for heart disease
... were genes coding for proteins that play critical roles in cholesterol metabolism and transport, known as apoplipoprotein A1 (APOA1), adenosine triphosphate binding cassette transporter A1 (ABCA1), and lecithin cholesterol acyltransferase (LCAT). Individuals with two defective copies of any of these genes...Jefferson scientists find gene expression pattern may predict behavior of leukemia
...otein synthesis, and are thought to play important roles in regulating gene expression in development. Rep...e scientists to gain a better understanding of the roles of miRNAs in cancer and provide targets for future drug development....Scientists identify compounds that mimic calorie restriction
...including changes in genes that may play important roles in heart disease and cancer. Calorie restriction i... one of a handful of receptors that play important roles in mediating the beneficial effects of calorie restriction. Our findings could be used to take a rat......ts in the area's old growth forests as well as the roles of insects, mammals, and birds in reconstructing the environment post-eruption. The dramatic transformation of Spirit Lake as well as the eruption's consequences on fish and amphibians will be addressed by Charlie Crisafulli (US Forest Service, Pacif...Bad news for pathogenic bacteria: Scientists find protein essential for bacterial survival
... bind to carry out their business." Knowing what roles ppGpp and DksA play in how bacteria respond to stress and other physiological stimuli may help scientists create new antibacterial drugs that target mechanisms specific and unique to harmful bacteria. "Conventional antibiotics aimed at killing bact...