'Rolling Circles' Provide New Way to Amplify and Detect DNA
...DNA, and then heated to unzip the strands for more rounds of copying. But suchthermal cycling is expensive, and the amount of DNA that scientists can prepare using PCR is limited by the need fora new DNA primer sequence for every strand copied. Even though scientists often use PCR to amplify a strand...New Gene Therapy Technique Results In 60 Percent Tumor Regression Rate
...n, so it's likely the patient would requireseveral rounds of this therapy. Once the HSV-TK gene began to express in the cell, the patient wouldreceive intravenous doses of ganciclovir. Tumor regression should be evident ina matter of days, Snodgrass says. Unlike chemotherapy, which isn't selective ...Bears Cubed: Virginia Tech Studies Three Bears, And Three Bears, And Three More Bears
... Fisheries. In the summer when the game department rounds up nuisance bears, it gives six toVaughan so he can study what happens to bears during denning, cubbing, and afterbirth. After the spring gobbler season, the mamas and cubs, who by then weighabout 12 pounds, are released back into the wilds of Virgin...New Microbial Insecticide As Potent As Bt
...ased from thenematode, kill the insect, and set up rounds of bacterial and nematodereproduction that turns the insect into a "protein soup," food for large numbersof nematodes. Moreover, the insect corpses left behind glow in the dark as the microbeproduces luminescent proteins in addition to potent insecti...Molecular Basis Of Leading Genetic Cause Of Infant Death Discovered
... an active form so that itcan be used for multiple rounds of splicing." In cells of patients with spinal muscle atrophy, the splicing process isdrastically compromised. Human motor neurons contain some of the highestconcentrations of snRNPs, as well as SMN, of any cells in the body. When thereis a d...Molecular Mechanism For Evolution Described
...netic oddities," explains Lindquist. After several rounds of inbreeding, as many as 90 percent of the fliese...r abnormality," Lindquist says. But after multiple rounds of breeding, Hsp levels were back to normaleven though the abnormalities persisted. "Once the freque...New Insight Into Genetic Cause Of Infant Mortality
...an active form so that it can be used for multiple rounds of splicing," explains Dreyfuss. It turns out that healthy human motor neurons contain some of the highest concentrations of SMN and snRNPs of any cells in the body. Perhaps not surprisingly, then, when there is a deficiency of SMN, motor neurons ap...Study Finds Protein Clues To Early Embryo Development
...hey remain off until the embryo has gone through12 rounds of division. "And if you don't activate genes during development butyou have a need for a large amount of proteins to be used during development,then you better have those proteins stored. Or you better be ready to translate,or activate, stored RNA t...Under the hood of a cellular transport machine
...esurface of the outer cell membrane. The pit then rounds and pinches off,trapping a section of membrane in a clathrin-coated vesicle. The membranesection, and the associated receptor proteins, are then carried into the cellfor processing, disassembly, or recycling. In a growing lattice, each newly added m...Study finds reliability problems with nerve test for carpal tunnel syndrome
...ical of carpal tunnel syndrome. Each underwent two rounds of nerve conduction tests, spaced three weeks apart, that electrically stimulated two nerves in the wrist and examined the difference in response time. Two U-M physicians performed the tests. In the first round, each physician tested both wrists of ...Virus study reveals how nature 'super-sizes' tiny structures
...cell wall, deposit their genomes and carry out new rounds of DNA replication." This presence of many cellular components, together with the common structural features found in the study, suggests that the two viruses may have evolved from a single-celled organism, Baker says. "These may be very ancient viru......r 2001. The new competition builds on two previous rounds of awards by HHMI forscientists in the Americas. In 1991, HHMI awarded 24 grants totaling $10.8million to support researchers in Canada and Mexico. In 1997, it awarded 47grants totaling $15 million for scientists in those two countries, plusArgentina...UCSF researchers identify regulator of critical brain messenger, hinting at therapy
...tions." The discovery of the glutamate transporter rounds out the understanding of the mechanisms by which neurotransmitters are released, and which therefore make neurotransmission possible. While the other classical neurotransmitters, such as dopamine and serotonin, are often released at great distances f...Dr. Thomas Starzl receiving prestigious King Faisal International prize this week in Saudi Arabia
...ndent experts examine all works in two elimination rounds and forward the list of finalists to special selection committees at the King Faisal Foundation....Remote monitoring of ICU patients lowers mortality rates, complications
...on system. The off-site clinicians participated in rounds via video conference, discussed individual cases with a senior member of the attending staff or bedside nurse at least twice a day, and were available by pager to discuss emergencies or patients newly admitted to the unit. Outcomes data during this ...Study offers insights into evolutionary origins of life
...hat could catalyze RNA formation. After successive rounds of testing, the Bartel lab isolated a ribozyme that didn't depend on a particular template sequence but could build a complimentary strand of RNA using information from any general RNA template. In fact, the ribozyme isn't hindered by longer RNA temp...All RBs are not alike: insight into RB in the plant cell cycle
...many times its original size, followed by multiple rounds of alternating S phase and cell division (mitosis). This multiple fission mechanism results in multiple daughter cells of uniform size. Implicit in this process are two fundamental cellular decisions: when to divide and how many round of division to...Study examines how prion disease adapts to new species
...ays Dr. Race. "It replicated faster in additional rounds of mice and even became more lethal to them." Furthermore, scrapie adapted in different ways in individual mice: the incubation periods varied widely, and the disease affected different parts of the brain. "It was not always the same pattern of adap...ORNL conducting field test of instruments to detect lead
... samples will include wipes archived from previous rounds of testing under the Environmental Lead Proficiency Analytical Testing program. Samples will have been prepared from dust collected in households in North Carolina and Wisconsin. Additional samples will be provided by the University of Cincinnati. Th...UM Cancer researchers test custom-made vaccine for non-Hodgkin's lymphoma
... In this trial, patients first receive eight rounds of chemotherapy with three drugs cytoxan, vincristine and prednisone. If they experience at least a 50 percent remission, they remain in the study and are observed for another five months while their bodies rest from the chemotherapy. If there is ...