Anti-cancer compound could cause serious liver damage, report University of Pittsburgh scientists
...lead investigators into believing that an agent is safe for use in humans," said Stephen Strom, Ph.D., associate professor of pathology at the University of Pittsburgh School of Medicine and senior author of the report. "We've shown that differences in the sensitivity of various species to the same compo...Biological legacies a key of ecological rebirth after Mount St. Helens eruption
...e exposed soil became aircraft carriers offering a safe landing for seeds carried in the air or tumbled along the ground by the wind, he says. Wind-borne seeds landed everywhere, of course, but those in the die-back areas had decided advantages. And, it turns out, the next-generation of these long-dista...Give it a thought -- and make it so
... by thinking their commands. "Virtual reality is a safe testing ground," says Bayliss. "We can see what works and what doesn't without the danger of driving a wheelchair into a wall. We can learn how brain interfaces will work in the real world, instead of how they work when someone is just looking at tes...Potential gene therapy carriers created that mimic viruses, without the risk
... decade ago, and much of the trouble surrounds the safe use of live viruses. The difficulty reached tragic proportions in September 1999, when an 18-year-old gene therapy patient died after being injected with a genetically altered adenovirus carrying a gene to control the boy's enzyme deficiency.Wooley'...Use of smokeless tobacco may lead to breast cancer, Wake Forest team reports
...increase "suggests that smokeless tobacco is not a safe alternative to cigarette smoking," said Spangler, assistant professor of family and community medicine. However, he cautioned that because of the small number of cases, the results "should be confirmed in other studies." The team found that that ...Tobacco smoke flavoring contains hazardous chemicals
...iences deems flavorings containing alkenylbenzenes safe for human foods. The additives, when eaten by humans, are thought to be safely eliminated by the liver. Cigarette smoke, however, delivers the chemicals to the lungs, where they spread through the body before the liver can screen them. In the study, ...'Real world' offers data to enhance safety of ambulance transport of children
...ard, to determine the optimal methods for ensuring safe transport of pediatric patients....Spring meeting press conferences
...tury We have not yet managed to assure a supply of safe drinking water to much of the world's population, nor to provide safeguards against disasters caused by extreme hydrological events. Doing so may become even more difficult as the climate changes. We must understand better the water cycle and more cl...Targeted Genetics presents clinical data on E1A cancer gene therapy
... analysis. "These data suggest that tgDCC-E1A is safe and will be useful in the treatment of head and neck cancer," said Dr. Reynolds. "Although patients in this study had very advanced disease, we were able to generate a 45% response rate using tgDCC-E1A as a single agent. Preclinical studies show th......udy found that intratumoral injection of Ad-p53 is safe at the administered doses and that the p53 protein is expressed. "Our CRADA program with the NCI is extending clinical work done by Introgen and Aventis by evaluating new routes of administration and additional indications worthy of further stud...Battery-operated pen quickly disinfects drinking water
... it possible for people to easily and quickly have safe supplies of personal drinking water in remote and isolated areas and during situations where drinking water supplies and other accessible water sources are at risk of being contaminated. The laboratory work for this project was completed at the Schoo...UNC-CH experiments reveal new 'pen' can disinfect water
... it possible for people to easily and quickly have safe suppliesof personal drinking water in remote and isolated areas and during situations where water supplies are at risk of being contaminated," Sobsey said. "There is a very big need for this, and it almost certainly will save lives." Users put a sma...UI biologist receives grant to study acoustic management of swine odor
...ch to identify and put into use an environmentally safe and economical solution. The research will utilize acoustic technology, which has the potential to drive chemical reactions and change the offending gases and waste into a safe, effective and locally-produced fertilizer." Soll noted that the univer...Study shows receptor molecule facilitates introduction of corrected genes into cells
...to the notion that you have to be careful and very safe when attempting gene therapy studies in humans," he said. "It's only when people try to rush ahead and cut corners do problems arise." Common on the airway side of cells lining the lungs, the G-protein-coupled receptor the UNC-CH team targets is a p...Targeted genetics presents promising data from cystic fibrosis clinical trial
... suggest that tgAAV-CF delivered via nebulizer was safe and well-tolerated at all doses evaluated. Effici... with mild disease. Data suggest that tgAAV-CF is safe and well-tolerated and is able to induce a reduction in the levels of IL-8, an inflammatory cytokine...Purdue joins Midwest effort to create biobased products
...and in creating cost efficient and environmentally safe catalysts that enable these conversions to be carried out," he says. "We will also develop genetically engineered microorganisms that will be used to produce specialty chemicals and ethanol from cellulose." Woodson says the National Research Council ...Amino acid supplements improve dialysis patients' health
... acid supplements may provide a cost-effective and safe method for improving the nutritional intake of some dialysis patients who are unable to meet their daily protein requirements, a Johns Hopkins study shows. "The technique increases serum proteins toward normal levels," says Mackenzie Walser, M.D., se...Fruit fly model could explain how mosquitoes carry malaria: new drugs and vaccines on the horizon
...is an urgent need for an affordable, effective and safe alternative to chloroquine. "The alternative drugs available today are very expensive and not a viable option for the vast majority of people suffering from malaria, who happen to live in some of the world's poorest countries," Schneider says. Anothe...Antimalarial drug may point way to new class of antibiotics
... If further testing shows these compounds to be safe and effective, the chemicals would represent a new class of antibiotics for the treatment of such problems as tuberculosis, and staphylococcal, streptococcal, and yeast infections. ...UF researcher: gene therapy effective in animal studies of Parkinson's disease
... trials, this information will be critical for the safe and efficacious planning of these trials."...