U of T researchers isolate gene for Crohn's disease
...recurring hospitalization and surgeries. Using DNA samples from family groups, Siminovitch and her research team employed a technique called positional cloning to first locate the chromosome containing the gene and then identify the gene. Their findings appear online April 11 in Nature Genetics ( www.nature....Glowing microspheres improve fluorescence measurements
...s research has shown that measurements of the same samples can vary by more than 100 percent depending on the instrument used and a variety of experimental conditions. The new reference material, combined with previously developed NIST standards and measurement procedures, now will provide an authoritative n...Better techniques needed to predict earthquake hazards, UC study finds
...regional seismic events. They took and tested soil samples at various depths and simulated hundreds of possible earthquake scenarios based on such variables as where a rupture might occur on the fault, the path it might travel, and how fast it might move. "We know that under very strong shaking the soil may ...Crime scene or nature reserve?
...eek describes how DNA from animal blood and tissue samples can be stored on record cards made from specialist...t the study. "Unfortunately the transport of fresh samples from the point of collection involves leakage risks and the possibility of sample degradation due to...Long-forgotten samples may help save species
...process." The newfound uses for the old samples also underscore the value of museum collections and fundamental science, Ó Foighil added. "When Jack Burch sampled these snails, he didn't know they were going to go extinct. It's a classic case of the unexpected utility of such basic, collect...Warning to preserve 'unique' red squirrel from extinction
...els there. For their study, the team analysed DNA samples from the pelts of more than 200 British and European squirrels held in museum collections dating back to 1861 to determine their genetic constitution. The research suggested red squirrels in the North-east have adapted really well to the man-made ...Three new South American fish identified
...new species while examining the contents of museum samples gathered from South American rivers in years past. Ironically, a previous Winemiller expedition had collected the fish without realizing the rare find because several similar fish were kept in a common specimen jar. Lopez-Fernandez was looking at th...Researchers say US military accidentally introduced tree pathogen to Italian estate
...he preserve. Gonthier and his colleagues collected samples of the pathogen from fertile fruiting bodies, allo... enabling them to narrow down the region where the samples taken from Castelporziano originated. They sequenced four different genes, all of which matched the ...Bay area to get unique x-ray microscopy resource
...resolution of five nanometers or better. However, samples must be sliced thin and put through an elaborate c...h-res images. With transmission x-ray microscopy, samples are rapidly frozen and need no further chemical alteration or staining to be imaged. Furthermore, 3...Researchers use novel technology to extract RNA from archive formalin-fixed paraffin-embedded tissue
... RNA from formalin-fixed, paraffin-embedded tissue samples archived for up to five years. What's more, the t...al samples." Hospitals are required to store tumor samples from surgical procedures in case further testing is needed. Biopsy tissue and other tissue specimen...Carnegie Mellon U. conducts first comprehensive proteomic analysis of developing animal
...ham, plc. Using DIGE, scientists label two protein samples with different color fluorescent dyes and then run both samples on the same gel, which separates proteins by size and electrical charge. A computer program analyzes...Undergraduate research experience advances education
... the PCR process to increase the rate at which DNA samples are replicated. Schreiber, a junior in chemical e...th Norton on a robotics product that would prepare samples for cultural analysis. "The REU was more of a biological experience and increased my interest in tha...Study points to a promising new test for myelodysplasia, a blood disorder often leading to leukemia
... "We believe that a study with a larger number of samples will validate our initial findings and thus pave the way for clinical application." Spivak noted that the new DNA test is the first molecular marker capable of distinguishing MDS patients as a group from patients with nonmalignant bone marrow disorde...Study shows benefits to newborns from federal ban on insecticides
...ith the babies' birth weight and length. All blood samples were frozen and stored at -70 degrees Centigrade i...ides. Subsequent analyses were performed on frozen samples at three different times -- spring 2001, summer 2002 and fall 2002. They found that prior to J...Antibiotics in the environment
...d tylosin antibiotics. Tests of a few swine manure samples showed that they contained as high as 7.9 mg/L chlortetracycline and 5.2 mg/L tylosin. The method developed by these researchers is very sensitive and can pick-up antibiotics in surface or ground waters at parts per billion levels. The study is publi...For some gorillas, local kin may mean local peace
...gorillas. By analyzing the DNA from fecal and hair samples of the western gorilla, scientists uncovered evide...ny Brook University, the researchers collected DNA samples to characterize patterns of paternity within and among western gorilla social groups. The authors fo...New tumor suppressor may play important role in deadly brain tumors
...dependent of p53." The research team first tested samples from 50 tumors of various malignancy grades for ev...r test that compared tissue from brain tumors with samples of nearby normal tissue found abundant ING4 levels in the normal tissue but significantly less in th...Gene chips help gauge chemotherapy's effectiveness in adult leukemia patients
...e remission length also proved successful in T-ALL samples taken from a separate group of 18 patients. Two conventional methods of predicting patients' outcomes measuring the white blood cell count and comparing the similarities between normal and cancerous cells were also evaluated and appeared to be less...Genes predict response of adult leukemia patients to chemotherapy
...of outcomes. The model was later verified by T-ALL samples taken from a separate group of 18 patients. Two conventional measures for predicting a patient's outcome the white blood cell count and the degree of differentiation (a comparison of the similarity between cancerous cells and their normal counterpar...Tips from the Journals of the American Society for Microbiology
...about the organisms responsible." In the study, samples of wood were taken from three expedition huts buil...adophora fungi were identified in two of the three samples and researchers determined the cause to be moisture in the ground from extreme melting and thawing d...