Tag: "screening" at biology news

Tumor Suppressor Gene Located In Liver Cancer Cells

...Next, the researchers began the arduous process of screening the large gene for one or more mutations that might disable it. Using a method to detect mismatches in genetic material, they compared strands of DNA from tumor cells and surrounding normal tissue, and discovered mutations in the tumor samples. Th...

International Research Team Clones New Skin Cancer Gene

...cancer may be fairly common. Bale suggests genetic screening for those who have had more than two basal cell carcinomas to determine if they are genetically predisposed. 3Through a simple blood test, we can identify people who are cancer-prone,2 he noted. 3For those who are, more aggressive monitoring and pre...

Genetic Alterations Linked To Cancer In Some Blood Samples

...cautions that the test does not appear useful as a screening test for cancer. "But it might be helpful in patient management for identifying patients with a very poor prognosis who may benefit from aggressive therapy," he says. The test works by identifying replication errors, or chromosomal deletions, in the...

Harvard, Duke Researchers Discover 'Off-switch' Inside Human Cells

...ls. In their experiments, the scientists began by screening a huge library ofhuman proteins to find those that interacted with activated G proteins.Structural analysis revealed that one of the candidate proteins they discovered,which they named RGS10, was closely related to the RGS family of proteinsfrom yeas...

Researchers Corral Millions Of Microscopic Membranes

...ould serve as the basis for improved cell and drug screening methods because it is ideally suited for automatio...t time. A potential biomedical application is cell screening of the type required for leukemia patients. Doctors must closely monitor the different kinds of cell...

Prostate Cancer's Aggressiveness May Be Predicted Early By The Ratio Of Free To Total PSA

...er deaths in the U.S." To help address the cancer screening controversy, the NCI has launched a large study to determine whether screening tests for prostate, lung, colorectal and ovarian cancers will reduce the number of deaths from these...

Menstrual Phase Linked To Ineffective Mammograms

...lse-negative mammogram resultswhen breast cancer screening is done during the last two weeks of their menstru...the medical community recognizes the benefits from screening aresmaller and slower to appear in younger compared to older women, we still do not knowwhy," says...

Chemists Develop High-Throughput Method To Synthesize And Screen Novel Antibiotics

...s. It is coupled with a high-throughput method for screening the compounds' activity. Thecomplete process takes about two days. "We have over 1,000 novel beta lactams," said Day. "Most ofthem test out as being very effective against a wide range ofbacteria." More importantly, several of the compounds are effec...

$3 Million From Defense Department Will Fund Next Phase Of UT Southwestern's Gulf War Syndrome Research

...ulf War veterans while we develop a cost-effective screening test and identify treatments for the sick veterans." The agreement between UT Southwestern and the Defense Department provides initial federal funding for the study. As results of UT Southwestern's studies and further phases of the research are revie...

Are CDC's 1997 Recommendations For Targeted Lead Screening Of Children Justified?

...icine argue that CDC's recentrevision of its lead screening recommendations for children which calls forlocal screening decisions as opposed to universal screening are insupportablegiven that "lead remains the greatest e...

Peutz-Jeghers Disease Gene Identified: Enzyme Loss Causes Polyps And Cancer

...ably exist and can now be identified. A special screening program for individuals with mutations in the STK11 gene is highly recommended to detect early stages of potentially malignant tumors. The ultimate aim in this field of research is to identify drugs that reduce the extent of polyp formati...

AAAS Announces Science Journalism Award Winners

...ween July 1, 1996, and June 30, 1997. Independent screening and judging committeesconsisting of journalists and scientists selected the winners. Robert Lee Hotz and Julie Marquis of the Los Angeles Times won the competitionfor the large newspaper category for their October 3 & 13--17, 1996, seriesentitled "T...

New Gene Alteration Find Points To Aggressive Leukemia Treatment

...ts with the ALL1 defect. Caligiuri suggests that a screening test for the defect, now availableat Ohio State, should be widely available this year. The international collaboration was funded by the Leukemia Society ofAmerica, the Lady Tata Memorial Fund, the Cancer Society of Finland andthe Coleman Leuke...

Reagent Strips Not Sufficient In Detecting Bacteriuria In Early Pregnancy

...cello and Richmond note that early antenatal urine screening should identify all cases to ensure adequate treatment is administered. In their study, the authors found that reagent strips for testing urine do not perform to a sufficient standard and therefore they advocate that all patients should have at leas...

National Toxicology Program Meets On Transgenic Animals

...s the use of gene-modified, or transgenic, mice in screening chemicals for cancer-producing potential, Feb. 5, 8:45 a.m. to 4 p.m., at the National Institute of Environmental Health Sciences Conference Center, 111 T.W. Alexander Drive, Research Triangle Park, N.C. NTP is headquartered at NIEHS and both are di...

Women Younger Than 30 Need To Be Screened For Chlamydia

Inexpensive screening of all sexually active young women under 30 forChl... The study, which compared results using three screening strategies atfamily planningclinics in Baltimore, showed that screening young women under 30 at fami...

Genetic Screening - Promise Or Threat? Penn Bioethicist To Explore The Dr. Jekyll-Mr. Hyde Aura Surrounding Genetic Testing

...he benefitsofthe genetic revolution in testing and screening is the inability of theUnited States to avoid the problems generated by a risk-rated health caresystem that fails to provide universal coverage." Caplan argues that unless we protect individuals from discriminationbasedupon their genes, insur...

Age-Based Screening Is Cost-Effective Method To Control Chlamydial Infection

...ics in Baltimore,Md. In addition to the age-based screening found to be most effective,investigators evaluated universal screening and screening with the criteriarecommended by the Centers for Disease Control and Prevention (CDC). ...

The Human Genome Project: Science, Law, And Social Change In The 21st Century

...urance industry Limits of state-mandated genetic screening Changing the human gene poolCan we? Should we? Among the speakers are genomics pioneer Dr. Eric S. Lander; gene therapy researcher Dr. James M. Wilson; scientist and patient advocate Dr. Nancy Wexler; attorneys Barry Scheck and George Annas; Commis...

New Fluorescence Technique For Ultra-Sensitive Enzyme Characterization Developed - Screening Catalytic Activity At The Single-Molecule Level

...nd demonstrating its potential for high throughput screening (PNAS 95:1421-1426, abstract: <a href="h...itability of dual-color FCS for high throughput screening has been demonstrated. Kinetics of biomolecular interactions like nucleic acid hybridiza...

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