Genetic clues found for common congenital brain disorder
...ersity of Chicago and an author of the study. "We see about 20 cases per year, but until recently, there was not even an understanding that Dandy-Walker had a genetic basis." "Knowing more about the genes also should improve our ability to make a prenatal diagnosis," he added, "which has always relied...Virus known for its photo ops makes its movie screen debut
...ched itself to E. coli's surface. "It was good to see the baseplate at such unprecedented resolution, bu...t's a story," Rossmann said. "We knew we needed to see more than one scene in that story if we were ever to understand its full meaning." The baseplate is ...Innovative 'ceramic-on-metal' hip replacements to undergo clinical trials
...lator' to carry out their work (picture available see details below). Professor John Fisher of the School of Mechanical Engineering is leading the research. He says: "An increasing number of younger and active patients now need hip replacements, and are demanding better-performing artificial joints. Th...Researchers report new gene test for isolated cleft lip and palate
...n higher than in the United States. "We wanted to see whether the variation could be found across multiple ethnic and ancestral groups," he said. "Or, was it confined to a single population?" The researchers found that the isoleucine variation was indeed present at a low but measurable level in all of ...Nucleic acid-amplification testing further safeguards nation's blood supply
...een 1999 and 2002. The researchers then looked to see which of these infected donations had been missed by tests to detect viral antibodies or antigens (proteins from the virus), the types of screening previously used. They concluded that NAT reduced the risk of HIV-1 and HCV infections associated with...MIT research that stops pain of needle jabs gets FDA approval
...e insertion of venous catheters. "Its wonderful to see the research we did at MIT get to the point where it can help people and relieve pain," said Robert Langer, the Germeshausen Professor of Chemical and Biomedical Engineering at MIT, who developed the device along with colleagues Joseph Kost and Profe......ary pieces of mRNA on the grid. Then by looking to see which pieces on the grid have RNA bound to them, t...own clock genes. So they designed an experiment to see if expressing the new genes in a cell could change the expression of known clock genes. To do this, ...New model can aid in understanding immune system diseases
...vides researchers with a model that allows them to see biological functions related to Epstein-Barr withi... looked at germinal centers in the mouse, we could see this tissue organization was disrupted," Bishop said. By studying this dysfunction in mice, the tea...ASU researchers demonstrate new technique that improves the power of atomic force micrscopy
...or and feeling those blocks to open their eyes and see that there are red Lego blocks, green Lego blocks ..."It means you can now follow a complex process and see what's happening, at the molecular level, to one of the components. We are now giving AFM chemical s...Genes can influence both alcohol consumption and dependence
... at any major celebration. From this study we can see more clearly that certain people are born with an increased risk of developing alcohol problems. An individual who is aware of a family history of alcohol-related problems needs to take efforts to reduce their own risk of problems, and society needs...Story tips from the Department of Energy's Oak Ridge National Laboratory, August 2004
...ctly an engineering challenge, the researchers now see the nation's electric power grid infrastructure driven by a complex combination of variables as diverse as rising demand, conflicting subsystems and societal pressures. Without a broader understanding of the interaction of those forces, a sandcastle ...Infants sighs may 'reset' breathing regulation mechanism as well as help lungs develop
...ill unclear. One intriguing area of research is to see whether sighs serve some sort of function to link ...mstances. The very long-term goal then might be to see if it's possible to identify those premature infants who are most at risk for problems of abnormal b...Leukemia stem cells identified by Stanford researchers
...ach of these populations on a separate lab dish to see which could renew their population. In the end, only one group of cells had the ability to self-renew, constantly dividing to produce both new stem cells and cells that matured. Jamieson examined these cancer stem cells and found they resembled norma...Joslin Diabetes Center launches research section on developmental and stem cell biology
...stem cell into an insulin-producing beta cell. "We see great potential promise in stem cells for someday preventing or halting diabetes, providing a vast supply of insulin-producing cells to transplant into individuals with diabetes, and for preventing diabetic complications. We're also keenly intereste...Excess thyroid hormone harmful to fetus
...o determine the consequences of an excess. We now see that having too much is just as bad as having too little. This tells us that hormonal replacement must be assessed and fine-tuned so as not to exceed the normal requirements." Physicians have not been able to study the effect on the fetus of excess ...The telomere crisis: A crucial stage in breast cancer
...erve in actual tissue specimens from patients, and see if they are similar." Using 3-D confocal microscopy and working first with breast-cancer tissue samples, at each stage the researchers assessed genomic instability and such correlated features as the amount of DNA content, signs of rearranged chromo...Excess levels of nitrogen, phosphorus linked to deformed frogs
...ogen into experimental ponds in Wisconsin and will see if they get a higher incidence of ramshorn snails, the parasites, and deformed frogs when compared to experimental ponds without those nutrients. Johnson and Chase's finding adds to the growing list of wrongs human activities have visited up...Biologists deciphering complex lemur scent language
...of scent marks in different ways. So, we wanted to see if there were messages encoded in the specific glands. "We knew these secretions varied in properties," said Drea. "The males' wrist gland gives off a low volume of clear liquid. And the shoulder gland produces a thick brown paste. And both male and ...Small animal imaging gives cancer clues
...nges in a mouse without surgery. "Not only can we see the DCIS-like lesion, but we can detect theearliest transition to an invasive tumor," Borowsky said. The modelcould be used to test treatments that would slow or stop thattransition in human patients, as well as to ask basic questions abouthow cancer...... with serious impacts on marine biology. "When you see the same thing happening with this regularity, it suggests that something is fundamentally different," said Jane Lubchenco, the Valley Professor of Marine Biology at Oregon State University. "This is a significant departure from normal conditions and...