Molecular fats prevent nerve sheath abnormality
... the myelin sheath is stripped away leaving entire segments unmyelinated, and that creates havoc with the elec...nodes are much larger, the gaps between myelinated segments are less regular - sometimes bigger and sometimes nonexistent. Sometimes the myelin segments overlap...Scientists map brain's primary memory network
...e electrodesdemonstrate that different portions or segments of the hippocampus are active at different timesduring the task depending on the type of memory function required. In the "News and Views" section of the same issue of Nature, Howard Eichenbaum, Ph.D., of theLaboratory of Cognitive Neurobiology at...Chemistry leaders expect longer lives, less pollution in the future
... front and center in the minds of leaders from all segments of the international chemical enterprise - academia, industry and government - when reflecting on the role they expect chemistry to have in the progress of society during the coming millennium. Their thoughts are captured in a special issue of the w...Fox Chase Cancer Center's Joseph Testa receives 1999 Irving J. Selikoff Award for Cancer Research
...sic genetic material, Testa has pinpointed missing segments on seven different chromosomes-the rodlike, DNA-packed structures that carry all the genes in a cell. In two of these chromosomes, he has identified genes that are missing or fail to function in mesothelioma cells. His research team is working to i......elphia research teamprocessed large numbers of DNA segments from that chromosome in preparation for the sequencing. TheHospital is considered a world leader in caring for children with a genetic disorder that results froma defect of chromosome 22. A significant event in the emerging era of genetic-based medi...Key developmental genes identified, linked to rare syndrome
...out showed substantial demethylation of chromosome segments called minor satellite repeats. These areas, located near the centromere - the central point at which the two strands of a chromosome are attached to each other - are believed to be important in maintaining a chromosome's structural stability. It a...Yale and Alexion report advance in spinal cord repair
...nerally are designed toinhibit the disease-causing segments of the immune system while preserving thedisease-preventing aspects of the immune system. The Company is developing threetechnology platforms: C5 Complement Inhibitors and Apogen T-Cell Therapeuticswhich together target severe cardiovascular and auto......nerally are designed toinhibit the disease-causing segments of the immune system while preserving thedisease-preventing aspects of the immune system. The Company is developing threetechnology platforms: C5 Complement Inhibitors and Apogen T-Cell Therapeuticswhich together target severe cardiovascular and auto...Clemson University Genomics Institute awarded $5.1 million by USDA and NSF
...ndation, the Clemson-led team willsequence and map segments of two chromosomes in rice. Rice is the world's most important food crop, feeding half the humanpopulation. Rice also contains the smallest genetic base, called "genome," formonocots, so it can be used as a model to understand the genetic ma...Argonne biochips may halt tuberculosis epidemic
...ulosis strains. The tests will be done on harmless segments ofgenetic material removed from tuberculosis bacteria. Clinical research -involving patients - is not expected to begin until the method has been provensuccessful. The biochips are designed to carry out thousands of biochemical reactionssimultaneousl...Advance may put gene chip technology on scientists' desktops
...the customized chips capable of deconstructinglong segments of DNA. The technique enables biologists to scour huge chunks ofanimal and plant genomes in search of the genes that promote disease, thegenetic switches that govern such biological phenomena as aging, and the DNAcodes that permit microorganisms to m...Images of enzyme suggest way to improve DNA sequencing
...s, called nucleotides, in DNA. It uses Taq to copy segments of DNA intochains of different lengths. Because Taq comes from a bacterium, Thermusaquaticus, that flourishes in hot springs, it can withstand the temperaturechanges necessary for copying. Four genetic letters -- A, T, C and G -- make up the DNA code...Single switch triggers two immune system genes
..." He added that previous experiments testing small segments ofDNA were inconclusive in defining the RAG1/RAG2... in cells expressing RAG2. By inserting such test segments into mice and looking for fluorescent B and Tcells, the scientists could determine whether those seg...UW-Madison team develops technique to create flu viruses
...oka says. The influenza genome has eight different segments of RNA, compared to only one in viruses such as ra...otechnology called plasmids, which are independent segments of DNA capable of replicating on their own. Plasmids are commonly used in science to transport genet...U-M scientists identify genes that make blood "thicker" and more likely to clot as we get older
... U-M scientists divided the human gene intosmaller segments and then recombined them to create more than 11 differentminigenes. Each minigene contained active transcription areas of the naturalgene's DNA plus adjacent regions. U-M scientists then used genetic engineering technology to insert these humanmini......nas transcription factors can find the appropriate segments of DNA amid thetangle. "The crucial point here is that if the wrong regions are read off at thewrong time, the result can be cancer or a developmental disorder," Luger said."DNA in a living cell is bent and highly distorted, and 98 percent...Computing device to serve as basis for biological computer
...ymer by matching these molecules to the analogous segments on thefirst polymer. However, unlike the ribosome, which only "reads" the messengerRNA in one direction, the computer edits the tape (first) polymer and may movein either direction. A Future Interactive Biological Computer The computer design ...The Origins Of Hereditary Breast Cancer -- Studies With Knock-Out Mice Reveal Underlying Mechanisms
... like 'molecular scissors'recognising and cleaving segments of the mouse genome. Rodents treated in thisway are known as 'knock-out' mice because a specific gene has been inactivated (knocked-out) specifically. One fifth of the mice that had their BRCA-1 gene removed from the mammary glandcells developed a tu...Alzheimer's Disease And Developmental Biology Linked Through Single Molecule
...ia. Notch is a large receptor protein with segments inside the cell and inthe membrane at the surface of the cell. When cells commit to become one oranother cell type, they present molecules that bind to the Notch receptor onneighboring cells to communicate this fact, so that the neighboring cell canc......," said Wiencke.The damaged, or chemically altered segments of DNA, known as DNA adducts, arephysical complexes in genes that are known to result from exposure tocarcinogens, and they are believed to be one of the first steps in thecarcinogenic pathway that ultimately leads to tumor formation. In tobacco smok...