Antibiotics alter GI tract microbes and increase lung sensitivity to allergens
...lls from the GI tract, T cells in the lungs become sensitized to the presence of ordinary mold spores, pollen or other allergens. The result is a hyperactive immune response, which can produce allergy symptoms or even asthma. To test Huffnagle's hypothesis, Mairi C. Noverr, Ph.D., a U-M research fellow in inter...Ontario researchers see increase in taste and odour-causing algae problems
...emselves are increasing or if local users are more sensitized to these issues. A study published in the current edition of the scientific journal Freshwater Biology examines sediment from 50 lake bottoms in the Muskoka-Haliburton region of Ontario. The results show taste and odour-causing algae have increased i...Common airborne substance makes asthmatics more sensitive to house dust mites: study
...e no clear-cut exposures to the allergens they are sensitized to," said Dr. Brian A. Boehlecke, lead author of the report, professor of medicine in UNC's pulmonary medicine division and member of UNC's Center for Environmental Medicine, Asthma and Lung Biology. "Now it appears that various airborne irritant...'Man's best friend' may be even better
...l of Applied Physiology. Methodology Beagles, sensitized to ragweed allergen at birth, were subjected to in...es, weighing 9.514.5 kg. Five dogs were neonatally sensitized to ragweed, three were their sham-sensitized littermates, and six dogs were nonsensitized. Newborn d...Bacterial infections alter allergic response
...ut only if the infection occurs before a person is sensitized to an allergen." Asthma and allergies have both be...the previously infected mice. When mice were first sensitized and exposed to ovalbumin, then infected with bacteria, they showed greater bronchial hyperresponsive...Rats depleted of salt become sensitized to amphetamine, show unusual growth of brain cells
... that have been repeatedly depleted of salt become sensitized to amphetamine, exhibiting an exaggerated hyperact...vered that nerve cells in the nucleus accumbens of sensitized rats have more branches and were 30 percent to 35 percent longer than normal. The nucleus accumbens...Common cholesterol drug prevents, reverses MS symptoms in mice
...f the mice with which the research team worked are sensitized to brain antigens so that they produce an over-abundance of cytokines, pro-inflammatory chemicals that inflame the CNS, causing demylination of nerve sheaths through the same mechanism and in the same manner as happens in human multiple sclerosis. A...Female vulnerability to drugs tied to estrogen, U-M researcher reports
... cocaine, Becker notes. For example, rats who are sensitized after repeated drug doses learn to self-administer cocaine faster and at lower doses than other animals. These changes in behavior persisted after the female rats, all of whose ovaries had been surgically removed, stopped receiving estrogen, Becker ......fication and that the stoppers be latex free, some sensitized individuals will be at risk for a potentially serious or fatal allergic reaction. Hamilton and his team make these recommendations based on a new study, reported in the June issue of the Journal of Allergy and Clinical Immunology, of 12 allergic and ...Response to cocaine linked to biological clock genes
...e insects' internal biologicalclock did not become sensitized to cocaine, a process in which repeated doses ofthe drug produce increasingly severe responses. "This opens up the field of drug studies to thinking about how a totallyunexpected set of genes functions in response to drugs," said Dr. Hirsh, thesenior......tical issue here is that blood components that are sensitized by inflammation have a greater tendency to initiate dangerous blood clots."When the body mounts an inflammatory response, it releases a substance called C-reactive protein into the bloodstream. Because the amount of C-reactive protein in the blood p...Combination Therapy For Brain Tumors Holds Promise For Longer Survival After Surgery
...rest cell growth in humancell lines, which further sensitized the cells to radiation. This approachworks in a similar way to Herceptin, the new breast-cancer-fighting drugawaiting FDA approval. Herceptin, a monoclonal antibody therapy, is based onthe basic research performed by the laboratory of Mark I. Greene,...Allergies To Rubber Affect 12.5 Percent Of Health Care Workers
...s, soit's important to identify both those who are sensitized and those who alreadyhave allergy symptoms," says ...By stopping exposure, we should beable to stop the sensitized but asymptomatic group from developing symptoms." Examination and surgical gloves are belie...