Tag: "sepsis" at biology news

UC Irvine scientists to develop vaccine to combat bioterrorism threat from deadly bacteria

...rn Australia. It is currently the leading cause of sepsis in northeastern Thailand, where infection rates are high during the rainy season since the bacterium thrives in water. Transmission occurs when humans and animals inhale dust bearing the bacteria, when they drink contaminated water, or when their ski...

JCI table of contents, 1 June 2004

...r advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response AUTHOR CONTACT: Peter P. Nawroth Medizinische Klinik I der Universitat Heidelberg Heidelberg, Germany Phone 1: 49-6221-568600; Fax 1: 49-6221-565226 E-mail: peter_nawroth@med.uni-heidelberg.de View the PDF of th...

Toll-free road from sepsis

...multi-organ failure and shock. The death rate for sepsis patients is in the range of 70%, and the health-care sticker price for such runaway infections is around $15 billion annually in the US alone. Strategies for treating septic shock are aimed at limiting the inflammatory response, as treatments to dir...

JCI table of contents, 17 May 2004

...multi-organ failure and shock. The death rate for sepsis patients is in the range of 70%, and the health-care sticker price for such runaway infections is around $15 billion annually in the US alone. Strategies for treating septic shock are aimed at limiting the inflammatory response, as treatments to dir...

Study examines whether giving good bacteria reduces infections

...o arrive at MCG Medical Center critically ill from sepsis following routine surgery. He first prescribes mor...ng diarrhea. "We know very well that the source of sepsis in these patients, 50 to 70 percent of the time, is their own intestines," Dr. Martindale says. "The...

International critical care doctors release first-ever guidelines for sepsis

...r to address the treatment of patients with severe sepsis were unveiled today at the 33rd Annual Critical Ca...es: More aggressive recognition and diagnosis of sepsis in all hospital departments Monitoring of central venous oxygen saturation levels Empiric, timely ...

JCI table of contents, 16 February 2004

...************************ Mast cells and surviving sepsis Sepsis the presence of organisms in the blood i...cell dipeptidyl peptidase I mediates survival from sepsis AUTHOR CONTACT: Paul Wolters University of California, San Francisco, San Francisco, California, USA...

Protein that fights bacteria and viruses cloned by Scripps scientists

...would be a boon, because the current prognosis for sepsis is dire. It can affect many parts of the body, inc...to the Centers for Disease Control and Prevention, sepsis is one of the ten leading causes of both infant and adult mortality in the United States, and, in 19...

Aspirin could reduce the risk of deadly infections

...ica's non-coronary intensive care units. Cases of sepsis are growing in number each year and are becoming increasingly resistant to antibiotics, making aspirin a possibly invaluable option for treatment. "The fact that aspirin has been used for pain treatment, to reducemortality due to heart attacks, and c...

An aspirin a day keeps Staphylococcus aureus away

... described as the organism responsible for causing sepsis and abscesses. Today it remains a leading cause of serious infections such as endocarditis, pneumonia, and septicemia and requires intensive antibiotic therapy, which is often unsuccessful due to the rise of antibiotic resistant strains. Aspirin has ...

JCI table of contents, July 15, 2003

... described as the organism responsible for causing sepsis and abscesses. Today it remains a leading cause of serious infections such as endocarditis, pneumonia, and septicemia and requires intensive antibiotic therapy, which is often unsuccessful due to the rise of antibiotic resistant strains. Aspirin has ...

Sepsis drug fights infection, decreases hospital care over two year study

...at people 75 and older who were treated for severe sepsis with the drug drotrecogin alpha activated (DAA) ha...y embraced this type of medical therapy for severe sepsis because of concerns about resource use and safety in older patients and questions about their subseq...

TSRI scientists show that rare genetic mutations increase susceptibility to sepsis

...es. About half of those who contract meningococcal sepsis are younger than the age of two, and the disease h...e took a large number of people with meningococcal sepsis and compared them to normal controls who were ethnically and geographically matched," says Beutler. ...

Critical therapeutics is awarded U.S. patents for methods to diagnose and treat inflammatory disease

... Increased levels of HMGB1 have been implicated in sepsis and other major inflammatory diseases including rh...ascade," or overproduction, of HMGB1 that triggers sepsis and other inflammatory diseases. U.S. patent number 6,448,223 B1, "Antagonists of HMGB1 for Treatin...

U.S.-German research consortium sequences genome of versatile soil microbe

...ent in 85% of P. aeruginosa clinical isolates from sepsis and urinary tract infections. "That suggests that those genes many not be specific for virulence," said Eisen. The researchers did, however, find many genes in P. aeruginosa and not P. putida that had not previously been identified as candidates for ...

LSUHSC research shows drug blocks enzyme that activates bacterial and viral toxins

...timated that about 750,000 American people develop sepsis each year and that more than 200,000 die from it. ... the factors contributing to the high mortality of sepsis (which has increased more than 90% in the last 20 years according to the National Vital Statistics R...

Discovery of activated protein C leads to lifesaving drug

... treatment for adults with life-threatening severe sepsis a blood disease that afflicts about 750,000 Americans each year, 215,000 of whom die as a result.Presenting the award was Vermont Senator Patrick Leahy, who was the recipient of the IPO Legislator of the Year award for his strong support of the inte...

The protective role of secreted CD14

...tingly, sera from individuals suffering trauma and sepsis accumulate high levels of sCD14. To test the poss...D14 from sera from people with varying severity of sepsis and studied its effects on LPS binding in cultured monocytes. Both the exposure of cells to LPS and...

FDA approves new treatment, Campath , humanized monoclonal antibody, for patients with B-cell chronic lymphocytic leukemia

... (Study 211) infections of any severity, including sepsis and pneumonia, were reported in about 44% of the study population. About 75% of these infections were serious (NCI-CTC Grade 3 or 4) in nature and about 20% were fatal. Slightly more than half of these serious (NCI-CTC Grade 3 or 4) infections occu...

New study shows immune-enhancing therapy reduces infections and shortens hospital stay by almost three days in critically ill

... critically ill patients who have suffered trauma, sepsis or major surgery, tube-fed (enteral) supplements s... When patients suffer trauma, major surgery or sepsis (the presence of pathogenic organisms, or their toxins, in the blood or tissues), their immune syste...

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