Duke Researchers Discover Candidate Susceptibility Gene For Autoimmune Disease
...mmatory diseasesincluding autoimmune disorders and septic shock," Blackshear said."This finding provides insight into a new gene that appears to regulateTNFa. It is possible that defects in this gene may cause people to be susceptibleto developing autoimmune diseases." The corresponding gene has been iden......rejection, multiple sclerosis, organ failure or septic shock, and also promotes HIV production in mono...e rate of survival in various endotoxin-induced septic shock syndromes.......s to elicit the production ofTNF-alpha and trigger septic shock. Now the researchers have shown that adisrup...ulture andanimal models of TNF-alpha induction and septic shock, comparing results withthe modified organisms to those elicited by wild-type Salmonella. Their...Medical Tip Sheet (A) For March 29
...may be akey component of the process that leads to septic shock, confirming suspicionsraised in other recent...evere bacterialinfections and endotoxin-associated septic shock that claim thousands of liveseach year. GenRISK Genetic Testing Program Offers Patients New H......ons. This immune system overreaction oftenleads to septic shock, for which no reliable treatments have been ...may be akey component of the process that leads to septic shock, confirming suspicionsraised in other recently published studies. In fact, the existence of th......uction in the potential of the bacterium to elicit septic shock, genetic stability in its safety-related mut...e potential for virulence and the ability to cause septic shock are enormously reduced through the use of highly stable genetic modifications. Research report......ons. This immune system overreaction oftenleads to septic shock, for which no reliable treatments have been ...ion that invades thebloodstream and often leads to septic shock. More than 20,000 people in theUnited States die each year from septic shock resulting from Gr...New Gene Holds Promise For Controlling Crohn's And Other Inflammatory Diseases
...lly attacks itself - includingperiodontal disease, septic shock, rheumatoid arthritis, lupus, Crohn's disease,and diabetes. "We believe this discovery offers new insights into how the body regulates thefundamental pathway involved in inflammation and opens up new ways to find andto treat currently untreata......ons. This immunesystem overreaction often leads to septic shock, for which no reliabletreatments have been f...ay be a key component of the process that leads to septic shock, confirmingsuspicions raised in other recently published studies. In fact, theexistence of the...INEEL launches comprehensive vadose zone management program
...m municipal andhazardous waste landfills, suburban septic systems, mining and petroleumproduction and agriculture are all filtering through the vadose zone. Researchers have known for years that soil can work as a natural filter forcontaminants, but they still don't fully understand how and to what extent. ...Microbial janitors tackle nuclear clean-up problems
... fromconcrete bridges to canals and waterworks, to septic systems. "You can see thisphenomena all around you -- you just don't realize it," said Johnson. "We'vejust optimized what is happening." At first, the research team tried using gases and liquid sprays to apply themicrobe/sulfur mixture. But that me...USGS scientists tracking environmental damage from Floyd
...ewater-treatment plants have been flooded, as have septic systemsand animal-waste lagoons. Rotting animal carcasses, chemical spills, and othercontaminants add to this concern. Some reports put the animal death tolls ashigh as 100,000 dead hogs, 500,000 dead turkeys, and more than 2 million deadchickens in ...Virginia Tech microbe-minerals group launches new field of study
... storage tanks, variousagricultural practices, and septic tanks. "The contaminants cover a huge rangeof organic and inorganic compounds. Examples of particularly toxic organicwastes are benzene, xylene, and toluene; and inorganic wastes are arsenic,chromium, lead, mercury, and nitrate," says Hochella. "Min......auts may one day be able to use their spacecraft's septic tank to keep in touch with ground control -- as long as they have plenty of sugar. Scientists in Michigan have developed a biofuel cell that creates a constant, low-power electricity supply by feeding glucose to common bacteria such as E. coli. Bioc...Anti-cancer compound could cause serious liver damage, report University of Pittsburgh scientists
...impractical to use in the clinic because it causes septic shock and liver failure....Little-known substance regulates inflammatory response
...is, Crohn's disease, rheumatoid arthritis and even septic shock. First discovered ten years ago, A20 was lar..., mice lacking A20 developed symptoms identical to septic shock -- plummeting blood pressure, widespread inflammation, kidney damage, decreased heart function...Sea grant study indicates potentially harmful human viruses in coastal waters
...ge. She used the method to show that raw sewage in septic tanks was leaking into coral reef ecosystems in the Florida Keys. For the study in California, Jiang began tracking the adenovirus, which is a direct indicator of human viral contamination. The virus is also the only in its class that contains fragme...New study could lead to better treatment of septic shock
ATHENS, Ohio A new study of septic shock could lead to a better treatment for the ill...ol, turning against the body in an attack known as septic shock. Those afflicted initially may experience flu-like symptoms followed by a drop in blood pressu......e. By 30 weeks, this fluid resembles liquid from a septic tank, Bruner said. Standard therapy calls for these fetuses to be delivered early, often by cesarean section. But complications include longer than average times in costly neonatal intensive care units, longer times before their first feedings (requ...Third piece completes deadly puzzle: Structure of anthrax toxin offers clues to treatment
...ie they release inflammatory agents that can cause septic shock, leading to death. The structure for protective antigen was published in February, 1997, and that of lethal factor in November, 2001. The structure of the third toxin, called edema factor because it causes fluid accumulation, provides the ...