New insight into control of parental gene expression in eggs
...omplicated ones that we are not able to predict by sequence analysis alone." An important future direction for the research, she said, is to identify more genes similar to H19 that are subject to CTCF-dependent imprinting control and to use RNA interference and other techniques to explore the nature of that c......at the first draft version of the honey bee genome sequence has been deposited into free public databases. The sequence of the honey bee, Apis mellifera, was assembled by a team led by Richard Gibbs, Ph.D., director of t...Study by UCSD gives new insight into how anthrax bacteria can evade a host's immune response
... anthrax toxin and determined where it acts in the sequence of steps involved in immune response." Macrophag... of lipopolysaccharide to this receptor sets off a sequence of events inside the macrophage, in which a series of proteins activate one another in turn. This ca......cess will be most visible. Building an animated sequence from individual frames, the scientists are granted a rare peek into the intricate dance of life on the molecular level. "This method," says Sagi, "represents more than a major breakthrough in the techniques used to understand enzyme activity. It chan...Scientists await first call from Beagle
...out 3 ft (1 m) onto the surface. The whole descent sequence from the top of the atmosphere to impact was to take less than seven minutes. The "pocket watch" design of Beagle 2 ensured that it would turn upright irrespective of which way up the little lander fell. After the onboard computer sent commands to r...New understanding of why brain cells die after stroke will lead to development of new treatments
...e brain cell. For years, it was thought that this sequence of events caused brain cells to die from stroke. For this reason, many experimental medications for treating strokes were aimed at blocking the effects of glutamate on NMDA receptors. Although it worked in the lab, the medications failed to reduc...Chimp vs. human DNA: what's in the 1% difference
...ut we found hundreds of genes showing a pattern of sequence change consistent with adaptive evolution occurrin...d Mark Adams. Celera generated some 18 million DNA sequence "reads," or about two-thirds as many as were required for the first sequencing of the human genome. ...Science's breakthrough of the year: Illumination of the dark, expanding universe
...e Self-Reliant Y Chromosome: In 2003, the genetic sequence of the human male Y chromosome revealed why this loner chromosome doesn't need a partner. It has duplicate genes, arranged as mirror-image "palindromes." Thus, when mutations arise and a new gene copy is needed, a twin copy is on-hand. ...Lifestyle accounts for difference in chimp, human genome
...ut we found hundreds of genes showing a pattern of sequence change consistent with adaptive evolution occurrin...d Mark Adams. Celera generated some 18 million DNA sequence "reads," or about two-thirds as many as were required for the first sequencing of the human genome. ...Academy Harbor Consortium releases letter on mercury to President Bush
...at control of mercury air emissions starts a clear sequence of events that can better protect public health: early control of mercury air emissions will lead to reduced atmospheric deposition of mercury to surface waters where mercury moves up the food chain to fish. The sooner levels of methylmercury in fis...Scientists discover way to streamline analysis of maize genome
...mplex structure has greatly complicated efforts to sequence the genome of maize, which is one of the world's m...o streamline the way that researchers identify and sequence the DNA in those gene-rich islands, scientists at The Institute for Genomic Research and collaborato...Less is more: New technology captures gene-rich DNA segments
Obtaining genome sequence information frequently leads to breakthroughs in t...or much larger than the 3-billion letter human DNA sequence and have a high proportion of so-called repetitive DNA that is difficult to sequence and contains fe...'Panning for gold' in the maize genome
...tructure and physiology. With so much non-gene sequence to deal with, it has not been feasible to sequence and assemble the whole maize genome with current technologies. Thus, it is a major shortcut to capt...'HapMap' scientists provide detailed plans
... in a given region of DNA to infer the rest of the sequence -- possibly tens of thousands of building blocks long. So instead of having to sequence each person's genome, future studies could merely identify variants in key positions (and thus deter...Mapping a road to understanding human health
...rapies are determined in part by variations in DNA sequence scattered throughout our genetic sequence called single-nucleotide polymorphisms, or SNPs. Many regions of the human genome bear common, tellt...A first glance at global genetic networks
...gene expression data from microarrays with genomic sequence information to explore genetic networks. Analyzing...he thousands of uncharacterized sequences found in sequence databases. This model presents a framework to explore the underlying properties that govern the desi...'Suicide proteins' contribute to sperm creation
...cellular processes. Apoptosis, a highly controlled sequence of events that eliminates dangerous or unnecessary cells, contributes to a wide variety of developmental and physiological processes--in a developing embryo, apoptosis creates the space between fingers and adjusts nerve cell populations to match the ...Tools from the Human Genome Project reveal a versatile microbe
...isciplinary effort determined the complete genetic sequence of Rhodopseudomonas palustris, a bacterium that co...tablished the Joint Genome Institute (JGI) to help sequence the human genome. With the completion of the human genome, the DOE has turned the JGI's considerable...Map of genes in plant root yields new tool for exploring tissue development
...bidopsis became the first plant to have its genome sequence completed. The National Science Foundation, a key funder of the sequencing effort, then launched "Arabidopsis 2010," a multinational program to determine the function of the all of the plant's genes by the end of this decade. According to Joanne Torn......bidopsis became the first plant to have its genome sequence completed. NSF, a key funder of the sequencing effort, then launched "Arabidopsis 2010," a program to determine the function of the all of the plant's genes in this decade. (It, too, is part of a multinational effort.) The gene-expression map annou...