Tag: "sequencing" at biology news
Some 400 'fragile regions' of genome more vulnerable to evolutionary breaks
...nd their study grew out of the first giant genomic sequencing
projects, funded in part by the National Institutes of Health. Those projects resulted in DNA sequencing
of the human and mouse genomes. In December 2002, that comparison led the scientists to compute 281 ...
NHGRI study may help scientists develop safer methods for gene therapy
...entifying the insertion site by capturing and then sequencing
a small bit of the human genome immediately adjacent to where the retrovirus inserted. "Now that a high-quality, finished copy of the human genome is available in public databases, it only takes the sequence of 30 base pairs (the chemical subunits t...
Gene clustering helps rice plants fight pathogens
...-author of a new research paper that describes the sequencing
of the rice genome's chromosome 10. The paper appe... of eight different groups the rice chromosome 10 sequencing
consortium representing various universities and institutes worked together to sequence and charact...
Going with the grain: A tale of rice's smallest chromosome
...," Plesset said, "is a result of the limitation of sequencing
technology. As new technologies become available, these gaps will be filled." The work reported in Science is a part of the international collaboration to sequence the entire rice genome completely. Two of the other 12 rice chromosomes, numbers 1 a...
Twice as many predicted genes in 'finished' rice chromosome
...ce genome. Robin Buell, who leads the rice genome sequencing
team at The Institute for Genomic Research (TIGR), says the "finished" sequence which helped researchers identify about 1,700 additional rice genes shows the importance of completing a draft DNA sequence. "This work clearly demonstrates the importan...
Rutgers research takes aim at world hunger
... their colleagues have announced completion of the sequencing
of the genetic structure of rice chromosome 10 - the first to date. Their novel approach, which defined both the order of the genes and their physical locations, is a major step in the direction of improved yield and productivity of the world's most...
DFG to establish 14 new priority programmes
...ith the patient's immune system. In this work, the sequencing
completed for the genomes of a number of fungi that represent a danger to humans offers an outstanding starting point for using functional genome analysis to examine the questions that have been raised. (Coordinator: Prof. Dr. Axel Brakhage, Universi...
Gene mapping key to unlocking human secrets, says geneticist
... advances in human and animal genetics have led to sequencing
the human genome, mapping the severe acute respira...nvolves a string of three billion figures. Genetic sequencing
is the ultimate map, like knowing every inch of the road, Womack said. Mapping as we currently do i...
U. of Colorado scientists discover four new kingdoms of life
... the soil organisms at once. Comparing their gene sequencing
results with those of known eukaryote organisms allowed them to discover the sequences from the four new kingdoms. Although they have the sequences of four previously unknown kingdoms, they have not yet identified the specific organisms themselves, s...
Computational method identifies genes that regulate cell's machinery
... global perspective. The recently completed genome sequencing
project enabled the development of microarray assays that measure the expression levels of thousands of genes in one experiment. These essentially give the scientists a snapshot of how much each gene is being used in the cells they examine. A typical...
Genetic reconnaissance identifies new colon cancer genes
... and related enzymes. To reduce the amount of gene sequencing
required, they focused their search on mutations in the "kinase domain" of these enzymes, which is the region that is principally responsible for enzymatic activity. "The kinase motifs are fairly stereotypical," said Markowitz. "They always include a...
JGI and Diversa Corp. announce large-scale microbial sequencing collaboration
... in GenBank within six months of the completion of sequencing
to allow public access by scientists around the wo...to tackle the larger and more complex challenge of sequencing
microbial diversity." "We believe the scientific, environmental, and commercial benefits from this ...
Anthrax: 'A soil bug gone bad'
...ax detection and diagnosis. Since the B. anthracis sequencing
project was started in 1999, TIGR had been posting...he complete genome of the Ames strain, TIGR is now sequencing
several other strains and isolates of the anthrax bacterium for comparitive genomic studies that wil...
UC Riverside scientists contribute to study that unveils genome sequence of bread mold
...nt from the National Science Foundation funded the sequencing
done at the Whitehead Institute Center for Genome Research. The analysis performed in Borkovich's laboratory was funded by a grant from the National Institutes of Health....
Gene discovery may shed light on carpel tunnel syndrome and Lou Gehrig's disease
.... His laboratory has been involved in mapping and sequencing
chromosome 7 as part of the Human Genome Project. "This discovery is another piece of a jigsaw puzzle picture of how peripheral nerve diseases and motor neuron diseases happen," said Dr. Fischbeck, chief of the Neurogenetics Branch at NINDS. Dr. F...
Bread mold yields a genome first for filamentous fungi
...ject, but a highthroughput production effort," the sequencing
effort neverthelessyielded new insights into light... Cellular Biology, the evolution of the Neurospora sequencing
effort itself has been driven by a sense of communityamong those who study the mold. The first genom...
Study sheds light on Chlamydial pathogens
... of Asians who contracted SARS. In addition to sequencing
C. caviae, TIGR scientists had previously led the ...muridarum. TIGR and other research centers are now sequencing
other chlamydial species. "There is a great deal of interest in chlamydial species now because ...
An unexplored genomic terrain in a handful of dirt
...l-dwelling mycobacteriophages selected for genomic sequencing
came from zoos, backyards, and even the soil outside a tuberculosis sanitarium in India. Despite their humble surroundings, the phages may have quite a story to tell. "Phages represent the most abundant life form in the biosphere, with an estimated 1...
Researchers identify gene for premature aging disorder
...logies from whole-genome scans to high-throughput sequencing
of targeted DNA regions researchers determined the most common cause of progeria is a single-letter "misspelling" in a gene on chromosome 1 that codes for lamin A, a protein that is a key component of the membrane surrounding the cell's nucleus. Spec...
Genetic blueprint for Q fever bacterium unveiled
... that can be aerosolized. A report describing the sequencing
project will be published online this week in The ...In recent years, NIAID has supported the completed sequencing
efforts for approximately 30 medically important microbes, many of which are causative agents of eme...
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