The future of HIV therapeutics is brightening, according to Gladstone Institutes Director
...though these HIV co-receptors were identified only seven years ago, basic studies performed by both GIVI investigators and scientists around the world have helped accelerate clinical development of CCR5 antagonists as a new class of anti-HIV drugs. Several major pharmaceutical companies are now racing to t...Highlights of American Chemical Society national meeting in Philadelphia, Aug. 22-26
... tasked with overseeing the clean-up fumigation of seven sites, including five mail facilities. "Decontamination of civilian sites in the U.S. affected by known agents of bioterrorism was never performed prior to the 2001 attacks," says Dorothy Canter, Ph.D., EPA's Chief Scientist for Bioterrorism Issues. ...Meteorites supplied Earth life with phosphorus
...ones we found was P2-O7 (two phorphorus atoms with seven oxygen atoms), one of the more biochemically useful forms of phosphate, similar to what's found in ATP." Previous experiments have formed P2-07, but at high temperature or under other extreme conditions, not by simply dissolving a mineral in room-tem...Anticancer drug zebularine specifically targets tumor cells
...looked at the effects zebularine had on a panel of seven different human tumor cell lines, and compared the...ecked. What the researchers found was that, in all seven cancer cell lines, treatment with zebularine slowed tumor-cell growth by anywhere between 32 and 68 ...Restoring sweetgrass to the South Carolina lowcountry
...youngest 41, with a mean age of 44. "We identified seven views and practices common to all of the basket makers," says Halfacre. "Most had purchased sweetgrass from collectors, and they all identified residential development as the reason the grass has become unavailable." The high price basket makers pay ...Newly discovered protein may be key to muscular dystrophy
...nts -- a model for human muscular dystrophy. While seven of the mutants involved defective DGC function, five others resulted from variations in a previously unidentified gene. The team cloned this gene, snf-6, and found that its sequence was similar to genes in a family of mammalian neurotransmitter trans...When is a mouse like a test tube?
...jected the mice with an azide-mannose compound for seven days, then harvested spleens from the mice to look for the azide. As predicted, it appeared on the surface of spleen cells attached to sialic acid, with more azide on the surface associated with higher doses of the azide-mannose sugar. Azide-labeled ...Scientists visualise cellular handmaiden that restores shape to proteins
...ntists. Each unit of the cage or cap is made up of seven separate polypeptide chains. "It's huge," said Professor Iwata. "The cavity can accommodate even very large proteins inside. It makes the perfect environment for the protein to fold." It is the second structure of a chaperonin complex to be reported...Possible new cure for psoriasis
...st under four weeks, this period is cut to four to seven days in psoriasis patients. The reason is the greatly increased rate of cell division of the keratinocytes. They form a layer which separates the epidermis from the dermis, which lies beneath it. The ageing cells pass from this germinal layer to the ...Technology already exists to stabilize global warming
...hers created a graph that divides the problem into seven 1 billion-ton-per-year "wedges." (See figures.) In...ach option and compare alternative combinations of seven "wedges." Several of the options, for example, involve capturing carbon dioxide at power p...Method to visualize gene activity may provide insight into normal development & genome function
...tiplex labeling to visualize the activity of up to seven genes at the same time, but they predict it will be possible to increase this to 50. Newly developed, ultra-bright fluorescent molecules make the multiplex labeling technique possible. The fluorescent molecules were provided by Molecular Probes, ...NHGRI adds 18 organisms to sequencing pipeline
... interpret the human genome. The data from seven of these mammalian genomes will be used primarily ...ionally important region of the genome. The seven mammals in this subset are the African savannah elephant ( Loxodonta africana ), the European common...Dispute over life in Antarctic lake
...umbers of microbes in the accretion ice are two to seven times as high as numbers in the overlying glacial ice," says Christner. "This indicates that the lake is a source of life. All the data points to the fact that there are microbes and they're alive." But Bulat disagrees. "We don't have different resul...Depression traced to overactive brain circuit
...-remission and 19 controls either pills containing seven essential amino acids, such as lysine and valine, or identical-looking placebo pills. Subjects received either the active pills or placebos in repeated trials over several days in a blind, crossover design. Sixteen (59 percent) of the patients ex...Virginia Tech's smelly 'corpse plant' due to bloom Aug. 4
...lant to see and smell it. A flowering stalk can be seven to 12 feet in height and three to four feet in diameter. After the bloom dies, a leaf stalk resembling a tree sapling will begin to emerge. The plant was first discovered in 1878 in Indonesia, first cultivated at the Royal Botanic Gardens in England ...Urban heat islands make cities greener
...ures caused plants to start greening-up on average seven days earlier in spring. Similarly, in urban heat island areas, the growing season lasted eight days longer in the fall than the rural areas. The researchers used MODIS surface reflectance data to measure seasonal changes in plant growth for the ent...Firefly compound lights up 'protein dance' in living animals
...s to use this system to study interactions between seven or eight other important pairs of proteins." Luker KE, Smith MCP, Luker GD, Gammon ST, Piwnica-Worms H, Piwnica-Worms D. Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living a...Scientists build on case connecting inflammatory disease and depression
...Right now at the University of Illinois, there are seven professors and research associates with nearly $12 million in grants in the area of integrative immunology and behavior," Kelley said. "We plan to use that financial base as a foundation to write a program project grant proposal that will fund gradu...DNA tests point to extinction of 2 distinctive arctic bird populations
...oundland." Currently there are 19 "endangered" and seven "threatened" bird species in Canada. Three distinct bird species are known to have become extinct in North America since 1900. The study will be published in an upcoming edition of the Canadian Journal of Zoology. Also on the team, from the Queen's B......ampton. AMD is a worldwide problem, affecting some seven million people in the United States alone. Vision ...lthy controls. However, the researchers found that seven of the 402 AMD patients each had a different change in the FBLN5 gene that was not found in the he...