New software developed at Rensselaer predicts promising ingredients for new drugs
...ch a vast molecular database rapidly. The first shortcut describes the molecule, its shape and chemistry, i... the computer can use easily." Then, the second shortcut identifies which molecules have the right chemistry for a specific therapy. Using advanced pattern-r...Less is more: New technology captures gene-rich DNA segments
...ng Harbor researchers have now achieved a dramatic shortcut to sequencing the genes of corn. The approach should provide a similar boost to the sequencing and comparative analysis of other genomes in a wide variety of biological, biomedical, and biotechnological settings. The study, led by Cold Spring Harbor ...'Panning for gold' in the maize genome
...me with current technologies. Thus, it is a major shortcut to capture only the portion of the maize sequence containing its genes without having to sequence the entire genome. "Collecting the maize genes for sequencing is like panning for gold," said Jane Silverthorne, program director for NSF's plant ge...Rutgers scientists post a genetic road map to sources of disease
...e authors. Matise pointed out that SNPs provide a shortcut for pinpointing genes that may contribute to disease because the SNPs are both plentiful and easy to analyze. Many SNPs lie within genes associated with a disease, while others are near such genes, she added. "Our challenge was to calculate the reco...Researchers get to the root of cassava's cyanide-producing abilities
...rin content. But, said Sayre, shortcut processing techniques, which are frequently used during famines, can yield toxic food products. "If we could eliminate the cyano...International consortium launches genetic variation mapping project
...ther. "Essentially, the HapMap is a very powerful shortcut that represents enormous long-term savings in studies of complex disease," said David Bentley, Ph.D., of the UK's Wellcome Trust Sanger Institute. Since all humans descended from a common set of ancestors that lived in Africa about 100,000 years ago...Dartmouth researchers identify multi-tasking circadian protein
... Medical School geneticists have found a molecular shortcut from light reception to gene activation in their work to understand biological clocks. Their research has revealed that the protein called White Collar-1 does double duty: it perceives light and then, in response to light, directly turns on a key gen...UB scientists report fast, simple method of generating 'designer' RNA catalysts for proteomics
...able "Sugazyme" provides an efficient and economic shortcut to attachment of tRNA to unnatural amino acids. The UB method generates the first artificial ribozyme that performs two unique steps that lead to the generation of novel proteins. First, the Sugazyme is programmed to recognize an engineered (i.e. unn...Energy landscape paving: A better way to find a better way
...ed helplessly through a myriad of small towns on a shortcut to Chicago. How, then, does one find the shortest, cheapest, quickest way to do anything, from travel cross country to assemble a widgit? Especially if there are many pretty-good solutions? Often, the answer lies in statistical physics. Since the 198...Rutgers scientists mapping DNA links to complex diseases
...tional genetics Tara C. Matise. SNPs provide a shortcut for pinpointing certain genes that may contribute to disease, says Matise, because they are easy to locate and easy to use as markers to track genes that may have an impact on genetic expression. Many SNPs lie within genes associated with a disease,...Study finds new way that brain detects motion
...ld be helped by this research since it describes a shortcut that programmers could use to help computers interpret a robots motion from real-world images....Mouse gene trap helps decipher brain's wiring diagram
...n. The technique, a type of gene trap, provides a shortcut for identifying - from among the tangled trillions of neural connections -- just the machinery involved in wiring up the brain during early development. NIMH grantee Marc Tessier-Lavigne, Ph.D., Howard Hughes Medical Institute (HHMI), and University......her. The investigators took advantage of a shortcut revealed by a mouse. Onemethod for identifying human genes is to examine comparable human and mousechromosomal regions, searching for genes already known to cause problems in micesimilar to those of concern in the human families. Although the...