More aggressive breast cancer tumors found in African American women
...en were four times more likely than white women to show significant alterations in the p53 gene. "This is the first population-based study to report a clearly significant increase in p53 mutations that is independent of race differences in other tumor characteristics, socioeconomic status and other biome...Fundamental change to Immunology 101
...plains Schwarz. "The textbook figures would always show an early split in hematopoiesis between the lymphoid lineages [T cells, B cells, NK cells], developing from a CLP, and the myeloid lineages. This is a very elegant model, and I was surprised to find how little direct evidence there was to support the...UCSD researchers are first to demonstrate molecular link between inflammation and cancer
...duce cancer incidence," Karin added. "Our studies show how NF-kB acts very early in the carcinogenesis process, in two different ways." The relationship between cancer and inflammation due to chronic infection has been suspected, but not proven, for many years. In a 1986 study, for example, one research...Oldest evidence for processing of wild cereals: starch grains from barley, wheat, on grinding stone
...t, but there has never been conclusive evidence to show that they were used to grind cereal grains or other types of plants, and not pigments. "It will be exciting to continue to analyze some of these older artifacts, to see if we can find evidence that they were used to process plants. We're trying to...Molecular therapeutics advance fight against brain cancer
...s with the deletion have slower-growing tumors and show a better response to chemotherapy; whereas, those without the deletion have relatively faster-growing tumors and are less responsive to chemotherapy, so radiation therapy is required sooner. "Given the expected increase in the life-span of patients w...News tips from the Journal of Neuroscience
...convey contextual details. This week, Moita et al. show that fear conditioning can induce such a re-mapping process. The remapping was more pronounced in rats that received contextual training. The authors suggest that place cells can convey not only the geometric details of an environment, but motivation...Education, monitoring vital for sport-fish eaters
...uded bass, yellow perch and walleye. Their results show that 87 per cent of the anglers had detectable blood mercury levels, all within Health Canada's acceptable range. The consumers all had detectable blood mercury levels, including two with levels above the accepted normal range. However, some had cons...Study shows how consensus is attained in a noisy world
...e into multi-cellular structures. The researchers show that a simple majority rule approach, in which each unit -- a person or a cell -- adopts the state of the majority of its neighbors within an intricate communication network, can efficiently lead to global organization. The model is adaptable and rob...New discovery may help transplants survive
...o) and living mice (in vivo), the team was able to show that VEGFR-3 was responsible for mobilizing APCs to move into the lymphatic system. Next, the research team blocked VEGFR-3 in mice using a specific protein (immunoglobulin) known to impede its function. When the VEGFR-3 was blocked, the APCs were a...Other highlights in the August 4 JNCI
...hildren's Hospital in Genoa, Italy, and colleagues show that by encapsulating an antisense oligonucleotide targeting an oncogene and activating the innate immune system in a liposome that specifically targets neuroblastoma cells, neuroblastoma-bearing mice lived longer than mice given any other treatment ...JCI table of contents, 2 August, 2004
...alifornia, San Diego, present intriguing data that show that the adaptive immune system, when activated to...uction of a cell cycle molecule called p27kip1 and show that these mice, after experiencing mechanical damage to an artery, had increased lesion formation w...New diagnostic technology helps justify earlier cataract surgery
... used to accurately measure the visual errors that show up as glare and other problems that cataract patients experience. This will give insurance companies a reliable and widely accepted means of testing for the effects of cataracts on patients' vision and for making reliable determinations of the medic...MSU group reviews Berkeley venture into brave new science funding world
...ministrators short of cash they will work hard to show that this is a good idea. You have to have some controls; you can't just say because it's a lot of money it's a good idea." Do a better job of educating the public on the specific nature of intellectual property, technology transfer, and the nature...Wheelchairs biomechanics, prosthetic development
...ber. This could explain other study results, which show a decrease in velocity and an increase in power output and in the time of the propelling phase, in relation to the wheel camber. These results provide information that must be taken into account in the search for the optimal regulation of the user-to...UCSB professor and director receives two national awards
...any in the very best peer-reviewed journals. These show an amazing diversity of interests and accomplishments. Jim is a great collaborator, as shown by the number and exceptional breadth of his co-authored publications. He has also trained as graduate students some outstanding mammalogists ." Reichma...New England forests at greater risk from air pollution
...t as long for a moderate level of air pollution to show its effects on forests. We should do what we can to lower that chance before it's too late to reverse the effects." She says that using lichen community composition as an indicator of air pollution not only will identify areas to target for managemen...Droughts like 1930s Dust Bowl may have been unexceptional in prehistoric times, new study suggests
... that were growing then, for sediment chemistry to show how much erosion was going on, and be able to deduce climate changes -- or the lack of them -- under way at the time?" Clark said. When he and his colleagues finally determined the correct intervals between samplings was about once every decade, "the...Two-pronged attack targeting EGF receptor hinders cancer cell growth
...ux combined with radiation in head and neck cancer show clear improvement in patient survival compared with radiation alone. The new study findings suggest that more effective EGFR signaling blockade with combination inhibitors might further augment these promising clinical results. "Predictive 'molecul...New UCF researchers, college will help fight Alzheimer's disease, cancer
...ived at UCF in the spring, hopes his research will show that taking stem cells from bone marrow in a patie...iced working with cells grown in lab cultures also show up in actual tumor cells. He also is beginning to study whether regulating levels of a protein calle......Rowan Chelbowski, M.D, Ph.D., results of the study show a significantly lower breast cancer incidence among black women. However, while they were less likely to develop the illness, they were also less likely to survive it. Dr. Chelbowski says: "Ethnicity had a major effect on poor prognosis cancer risk. ...