A New Molecular Marker For Prostate Cancer
...low levels of p27 protein in tumor cells have been shown topredict disease progression in breast and colon cancer. Researchers divided the 96 tumors into three groups, based on the percent oftumor cells in each sample expressing p27 protein. Fifty-three tumors had highlevels of the protein, with more than......sity School of Medicine in St. Louis. "Now,we have shown that those fibers also can enhance the transmission between thepainful stimulus and the neuron in the spinal cord." The researchers report their findings in the June 18 issue of thejournal Nature. The study was funded, in part, by a grant fro...Brain Antibodies Provide New Clues To Origins Of Tourette's
...d controls. "Brain imaging studies have shown changes in the shape and size ofthe putamen in Tourette's patients, reinforcing the idea that these antibodiesmay contribute to the disorder," says Singer. Strep infection is a leading suspect for the trigger in a small numberof patients beca...Taking The "Ouch" Out Of Needles: Arrays Of "Microneedles" Offer New Technique For Drug Delivery
...Prausnitz said. "Preliminary testing on humans has shown that insertion of microneedles into theskin does not cause pain." Before the microneedles could be used to administer drugs to humans, theresearchers must demonstrate their safety and effectiveness through extensiveanimal and human testing. Potentia...Researchers Discover Way To Grow New Kidneys In Rats
...king on it," Hammermansays. They also have shown that chimeric kidneys thrive and are not rejectedby rats' immune systems within 6 months of attachment to ureters. Hammermansuspects this partly reflects the host origin of the kidney's blood vesselsbecause foreign blood vessels are a major stimulato...New Microbial Insecticide As Potent As Bt
...tion to potent insecticides. Previous studies have shown that, in concentrated doses, the toxin can be usedas a spray or fed directly to insects. The greatest potential application,however, lies in transferring the toxin-producing genes from the bacteria tocrop plants. The incentive to confer crop plants w...Life In Antarctic Ice May Compare To Mars
...complicated thing," he said. "But experiments have shown you can get fairlycomplicated molecules and amino acids from the interaction of basic chemicalsand electricity." Giovannoni has studied bacteria all over the Earth, from the basaltrocks of deep sea floors to Antarctic ice cores, Yellowstone N......o find the new fungus in 10 frog species and have shown that the fungus kills frogs in laboratory trials. ...us in frogs in many zoos and have retrospectively shown it was present in one zoo as early as 1988. Investigations are continuing - to confirm the hypot......ogy at Pitt's GSPH. Previous studies have shown that combining protease inhibitors with tworeverse transcriptase inhibitors does not completely eliminate HIV from thebody, nor does triple therapy offer patients full protection from the virus ifthey discontinue the drugs or expose themselves to rep...Fauci To Present New Insights Into HIV Latency At 12th World AIDS Conference
During the past year, scientists have shown that HIV persists in a latent formwithin a relativ... AIDS Conference in Geneva, Switzerland. "We have shown that initiating HAART as soon as 10 days after the onset of thesymptoms of acute HIV infection does ...Summer Science: Where Have All The Honeybees Gone? UD 'Bee Guy' Asks Why--From America To The Amazon
...to "go for the gold," Caron says. His research has shown that theprice tag on a jar of honey can vary dramatically along the same stretch ofroad, but it's still a bargain. Priced at 0.19 cents per pound in 1937, U.S.honey now averages about $2.00 per pound, he reports. "Honey isn't essential for the human ...Wake Forest Study: Dermatologists Provide Better, Cheaper Care For Fungal Skin Disease
... to some degree,cancel it out." Other studies have shown failure rates of 45 percent forcombination drugs, compared with just 8 percent for single agents. The combination drugs cost more, too. Fleischer estimated that thecombination drugs cost the nation's health care system $10.3 million to $24.9m...Novel Liver Steroid Slows Brain Tumor Growth
...ll as other tumors. Squalamine, previously shown to have antibiotic and anti-canceractivity, inhibited the growth of brain cancers called gliomas implanted in theflanks of rats by disabling blood vessel growth, or angiogenesis, say theauthors of the studies, published in the July 1 issue of the jou...... "One of the important things this study has shown us is that thesuperficial appearance of an area might not be telling you the whole story,"said Hamrick. "Each situation has unique characteristics that make if verydifficult to say that tropical trees in a certain situation will behave this wayor tha...Denatured Proteins Rescued By Trio Of Chaperones
...uist, Ph.D., andcolleague John Glover, Ph.D., have shown that protein snarls can actually berescued by Hsp104 with the assistance of two other heat shock proteins. Heat is a protein's enemy. As an egg fries, its proteins, which are made ofchains of molecules called amino acids precisely folded i......noleic acid (CLA). Dr. Kritchevsky's research has shown that CLA, a fatty acid found predominantlyin whole milk, cheese and, to a lesser extent in beef, reduces atherosclerosis. An early indication of heart disease, atherosclerosis is characterized by yellowplaque deposits that accumulate in the arteries.......rom the mycelium cell wall of P. sojae that was shown to act as an elicitor in this nonhost system. Incubation of parsley cells with the elicitor resulted in dramatic biochemical changes in the affected plant cells, e.g., the generation of reactive oxygen intermediates (ROI), increased ion f...CSIRO Reduces 'Cellulite' In Oranges
...ree. "Assessments by growers last season have shown a 20-25 per cent reduction in the number of fruit showing visible symptoms," says Dr Treeby. "We have reduced the problem, not eliminated it," he says. "While the spray has lessened the incidence of albedo breakdown, the cause remains someth...Molecular Marker May Identify Bladder Cancer Patients Most Likely To Recur
...vide in an uncontrolled fashion. Earlier work has shown that bladder cancer patients with alterations in the p53tumor suppressor gene are more likely to recur or progress to metastaticdisease. In addition, p53 is known to be a primary regulator of p21, sincegenetic changes in p53 may lead to loss of p21 e......chemicals can be seen under high magnification, as shown in MariaEisner's SEM (scanning electron microscopy) picture of E. borealis pupal hairs on the cover of Science . . The tiny insect pioneered anendeavor in which human chemists, with their costly and sophisticated machines,only now hope to succee...