Scientists discover way to regulate the body's energy expenditure
...s Proceedings of the National Academy of Sciences, shows how the protein regulates the activity of a key gene responsible for maintaining the body's temperature, called uncoupling protein 1 (UCP1). The new protein, called RIP140, blocks the expression of UCP1, and causes the body to use up more e...When blood can't get to brain, special CT scan helps
...-- or isn't -- going. But newly published research shows that an innovative type of brain scan can quickly ...g the structure of brain tissue, perfusion CT also shows how much blood is present in the brain and how quickly it is moving. This is done by scanning the pa...UCSD study shows how we perceive world depends on precise division of labor among cells in brain
...ecific portions of the information. "Our work shows that deciphering the enormous amount of information that is conveyed to the brain at any time-point is a matter of division of labor between specialized neurons," explains Scanziani, an assistant professor of biology. "Each neuron literally 'picks' ...Yale scientists visualize molecular detail of RNA splicing complex
... the associations it makes as it reacts. The image shows an interaction with metal ions and the alignment of the RNA molecule segments. "The structure reveals how RNA, which is chemically very different from protein, is able to use metal ions to achieve a very similar reaction mechanism," said Scott Strob...Other Highlights in the June 2 JNCI
...ker Could Help Detect Prostate Cancer A new study shows how testing for an immune response to the prostate cancer biomarker alpha-methylacyl-CoA racemase (AMACR) could be used to help detect prostate cancer in men with intermediate prostate-specific antigen (PSA) levels. Although PSA screening for prostat...Cell growth and death controlled by single pathway in lymphoma cancer model
...offers a possible solution. The cell culture study shows that in a type of lymphoma, molecules involved in the NF-kappa B (NF-kB) signaling pathway -- responsible for pushing cells to grow uncontrollably -- also control the function of the p53 tumor suppressor protein whose function is demolishing those ha...Published research contains 'high level of statistical errors'
...shed this week in BMC Medical Research Methodology shows that a large proportion of articles in top science and medical journals contain statistical errors, 4% of which may have caused non-significant findings to be misrepresented as being significant. Thirty-eight percent of the Nature papers and a quarte...Brain disease research, particle physics meet in the middle (ware)
...of the NMI releases by BIRN, Grid3 and other teams shows that NMIs open-source and open-standards approaches can help scientists avoid reinventing the wheel and provide a common foundation for building customized applications. Worlds away from neuroscience, the Grid3 project faces similar challenges in dat...UW-Madison scientists find a key to cell division
...highly conserved across two very different species shows how ancient and conserved the process of cell division is." The team analyzed 160 key proteins - including 103 not previously known to function in cell division - and found that 58 percent caused cytokinesis defects if they were inactivated. "The pr...Molecular image of genotoxin reveals how bacteria damage human DNA
...blished in the May 27 issue of the journal Nature, shows exactly how the toxin is put together at the molecular level and damages human DNA. The structure also could help scientists to design new drugs to fight the wide variety of bacteria that use this toxin. The toxin, called cytolethal distending toxin,...VA/UCLA researchers pinpoint role of histamines in waking
...rch Laboratory and UCLA Neuropsychiatric Institute shows that brain cells containing the chemical histamine are critical for waking. Detailed in the May 27 edition of the journal Neuron , the findings show that the cessation of activity in histamine cells causes loss of consciousness during sleep, while c...White tea beats green tea in fighting germs
... and primary author of the research. "Our research shows White Tea Extract can actually destroy in vitro the organisms that cause disease. Study after study with tea extract proves that it has many healing properties. This is not an old wives tale, it's a fact." White tea was more effective than green tea ...Computer model shows increased US threat from soybean rust
...nited States in a relatively short time. "Our work shows that the U.S. is at high risk once the pathogen that causes the disease expands its range into the northern part of South America," said aerobiologist Scott Isard of the geography department at Illinois. "We have received credible reports that this h...Indoor mold, building dampness linked to respiratory problems and require better prevention
...ial for mold growth, there is little evidence that shows which forms of moisture control or prevention work best at reducing health problems associated with dampness, the report notes. In addition, materials designed to educate the public about the actual health risks associated with indoor dampness shoul...Moving targets: when it comes to patterns, motion gets factored in
...y affects pattern perception. Second, the research shows that during multi-slit viewing, observers can see fine spatial components that are theoretically impossible to recover without the aid of motion information. In contrast to general beliefs about how we perceive patterns, these findings indicate that ...Study may improve survival of transplanted livers
...f North Carolina at Chapel Hill School of Medicine shows that treatment with nitric oxide after storage may dramatically improve the viability of transplanted livers. About 5,000 liver transplants are performed annually in the United States, and a key factor ensuring success is maintaining a healthy donor ...Researchers target deficit irrigation for wine grapes
... "Deficit irrigation is a new concept in Texas. It shows promise, but it will probably only work in low rainfall areas such as West Texas where most of the plants' water needs are met by irrigation." Hellman and research associate Ashley Basinger began evaluating regulated deficit irrigation at the Newso...Many scientists believe the dog genome holds information that will benefit human health
..., Parker contacted breed clubs and traveled to dog shows to collect DNA samples from five animals from each...uch as the Alaskan Malamute and Siberian Husky and shows the closest relationship to the wolf, the direct ancestor of the domestic dog. "This group may be te...First genetic comparison of purebred domestic dogs produces surprises
...e cheek-swab DNA samples from purebred dogs at dog shows and directly from owners. "While we only analyzed eighty-five breeds of the hundreds of recognized breeds, those eighty-five included the great majority of popular breeds," said Ostrander. "Just the top 20 breeds, which include the Labrador Retriever...Cancer drug resistance research leads to possible therapeutic target for Alzheimer's disease
...tions from Alzheimer's patients, the ABCA2 protein shows unusual patterns of expression," Tew added. "That also suggests that this transporter has a possible role in Alzheimer's." Tew was chairman of pharmacology at Fox Chase until this May. He is now chairman of the Department of Cell and Molecular Phar...