Tag: "signatures" at biology news

Atacama rover helps NASA learn to search for life on Mars

...is going a step further by trying to understand if signatures of microbial life can be unambiguously detected remotely using a robotic platform," Cabrol said. "These robots and science payloads will be a wonderful precursor to human exploration and excellent 'astronaut/astrobiology assistants' when the time com...

Researchers devise potent new tools to curb ivory poaching

...d used a statistical method to extrapolate genetic signatures to fill in gaps between sampled populations. Matthew Stephens, a UW associate professor of statistics, developed a model allowing the researchers to build genetic profiles for elephant populations from which they do not have genetic samples. The mod...

Columbia research to examine gene influence on severity of peridontal disease, therapy response

...apapanou and his team will examine gene expression signatures to define different subtypes of the disease in order to understand the molecular processes involved in each subtype. The research will take advantage of contemporary gene expression profiling technology, similar to that used to study the behavior a...

Congress to fund Sequim-based coastal security research effort

...designed to selectively capture and preconcentrate signatures in the marine environment. "The vision is to establish a network of sensors and biosensors that can be easily and inexpensivelydeployed across wide regions on or near the shore. This network would serve as an early warning system for coastal security...

Jefferson scientists find gene expression pattern may predict behavior of leukemia

...hat is the only common denominator between the two signatures with good prognosis." But before using miRNA expression as any kind of clinical biomarker, says Dr. Croce, the results need to be verified in a clinical trial screening thousands of patients. Dr. Croce and his colleagues had previously shown that de...

Full promise of genomics in disease research yet to be realized

...se of SARS. Genomics has identified the genetic signatures that today are being used in bioforensics to allow authorities to investigate cases of suspected bioterrorism. Some of the recent drugs in the arsenal against AIDS were designed using information from the HIV genome. Certain themes have emerged fro...

Gene profiles could improve acute leukemia diagnosis and lead to better treatments

...s study also demonstrated that the gene expression signatures identified in the pediatric leukemias could also b...gher incidence. The identification of AML subtype signatures is important because the outlook for a particular patient depends on whether he or she has the subty...

'Search and destroy' protein turns tables on HIV

...oteins can account for all the anti-HIV mutational signatures apparent in HIV DNA of AIDS patients. But what function the proteins perform in non-HIV-infected people is unknown. It is also unclear whether the defense mounted by the APOBEC proteins--when not foiled by VIF--would be enough to protect a person fro...

Gene expression ratio identifies risk of recurrence in breast cancer patients receiving tamoxifen

...ficer, began to investigate whether such molecular signatures could help identify which drugs would be the best options for particular patients. The researchers gathered tumor samples from patients who had received tamoxifen treatment for early-stage, estrogen-receptor-positive breast cancer. They identified ...

Guiding gas exploration: U-M research offers inexpensive tool

... Michigan and Amherst College are reading chemical signatures of water in those areas to pinpoint places where gas is most likely to be found. Their most recent work is described in a paper published in the May/June issue of the Geological Society of America Bulletin. Natural gas forms when organic materials...

Researchers identify unifying code among diverse classes of natural antibiotics

...obial peptides. The discovery of multidimensional signatures in host defense peptides by Drs. Yount and Yeamen will help to create molecules with strategic functions, potentially enabling new and effective treatments for drug-resistant infections. Moreover, it validates a new method to identify cryptic structu...

Pollution history documented through shell remains provides tool to study ecosystem change

...esent the paper, "Using geochemical and taphonomic signatures of freshwater mussel shells to explore industry-related extirpations in the North Fork Holston River, Va. (60-8)," at 10:40 a.m. Saturday, March 27, in the Lord Thomas Fairfax Room of the Hilton McLean Tysons Corner. Co-authors are Virginia Tech geol...

First large-scale trial of genetically personalised treatment for breast cancer to start soon

...endent trial to study the role of molecular tumour signatures in breast cancer will get underway in the coming year, scientists announced today (Friday March 19) at the 4th European Breast Cancer Conference. TRANS-BIG, a translational research network involving about 40 partners from all over Europe and from...

Profiling prostate cancer

...expression profiling method to determine molecular signatures that could distinguish subgroups of patients with different disease outcomes. The algorithm was developed utilizing an analysis that assessed expression profiles of over 12,000 genes from 100 different tumors. Five highly discriminating gene-expres...

JCI table of contents, 15 March 2004

...expression profiling method to determine molecular signatures that could distinguish subgroups of patients with different disease outcomes. The algorithm was developed utilizing an analysis that assessed expression profiles of over 12,000 genes from 100 different tumors. Five highly discriminating gene-expres...

Genetic profile, not clinical appearance, to determine tumor treatment

...ase. This technology will help identify metastasis signatures and provide logical targets for drug discovery. This moves us closer to a time when we will treat patients based on the genetic profile of the tumor rather than the clinical presentation of the disease. Finding targets that are differentially express...

A world ruled by fungi

...h will now focus on whether the similar biological signatures at these mass extinctions reflect similar causal mechanisms....

Baker's yeast rises from genome duplication

...may also be fruitful to search for similar genomic signatures of WGD in other organisms. It will be interesting to see just how far such distant echoes of genomic upheaval may be traced," the authors said. Kellis is also part of the MIT Computer Science and Artificial Intelligence Laboratory, and Lander is a pr...

UNC study may improve gene therapy safety

... the start of a useful database of gene expression signatures for people involved in vector development." The ne...ue exploring the vector-associated gene expression signatures in other cell types and to extend the work to whole animals. "I think everybody involved in designin...

Experimental Biology 2004 - Translating the Genome

...mmation and vascular pathobiology, gene expression signatures of cancer, and other subjects related to translating new molecular pathology understanding into medical advances. The American Society for Nutritional Sciences (ASNS) includes 13 minisymposia built around research presentations on aging and chronic ...

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