Researchers adapt RNA interference to study gene function on a large scale
...on, they can begin to group genes according to the signatures of their response in such assays. Such groupings will offer a guide to further biological studies to map the functional cellular protein machinery that the genes produce in living organisms. "The idea is that with this information we might be able ...Fish, FRAMES and sticky chemicals net technology award for Pacific Northwest National Laboratory
...ngredients in pesticides and herbicides and can be signatures of illegal chemical or nuclear weapons production. With heated equipment and clear Teflon sheet walls, the chamber is so nonstick that users can identify semi-volatile, volatile and particulate chemicals; understand their life cycles; and determine l...Are fish made of maple leaves?
...strial carbon fuels aquatic production. The carbon signatures of the zooplankton reflect their dependence on both internal plant production and terrestrial organic matter. Zooplankton are a dietary staple for many fish, especially very young life stages . "Our results," notes Cole, "tell us there is not nearly ...Gene may be key to evolution of larger human brain
... and in the vast number of cases, we see only weak signatures of adaptive changes," said Lahn. "So, I was quite ...at this one gene shows such strong and unambiguous signatures of adaptive evolution -- more so than most other genes we've studied." By contrast, the researchers'...Keck Foundation grant launches interdisciplinary brain research at Illinois
... the ultimate goal of identifying natural chemical signatures to restore proper wiring and functioning in malfunctioning brains....Bacteria discoveries could resemble Mars, other planets
...omplex," Storrie-Lombardi said, "and detecting the signatures of living systems in Dr. Fisk's study demanded close cooperation among scientists in multiple disciplines and resources from multiple institutions. "That same cooperation and communication will be vital as we begin to search for signs of life below...Abandoned penguin colonies may help refine Antarctic climate studies
...limate records." Scientists typically use chemical signatures in marine sediments, ice cores and other natural records to piece together a picture of what the Antarctic climate looked like thousands and even millions of years ago. But those records do not provide a highly defined or detailed picture of climate...Bird 'breathalyzer' helps assess migratory diet
...its feathers. Podlesak is the first to use carbon signatures in different tissues from the same bird to create a dietary timeline for migrating birds. "The signature in the feather tells us what the bird ate on its breeding grounds a month or two ago; the signature in its red blood cells tells what it ate wi...Researchers measure the 'heat of life,' offering clues to DNA damage
... incorrect DNA synthesis. The differential energy signatures signal the presence of DNA damage, potentially repairable by protein systems inside the cell or specifically designed drugs administered from the outside, or both. "Knowing the nature and magnitude of the forces involved in correct and incorrect DNA ...Isotopes from feathers reveal bird migration
...he top of food chains. The result is that isotopic signatures in the feathers of the top predators reflect the area where the food was consumed while the feathers were grown. Carbon isotopes, also found in feathers, vary with latitude due to different growing conditions for plants across the continent. Even n...National lab trains U. S. customs agents against WMD
...chemical agents such as mustard gas; the radiation signatures of reactor-grade and weapons-grade plutonium and uranium compared with industrial and medical isotopes; and the operation of missile-delivery systems. Hands-on training includes instruction on advanced detection technologies like radiation pagers, g...Research: Coral reefs' decline actually began centuries ago
...hows the downfall of those resplendent and diverse signatures of tropical oceans actually may have begun centuries ago. According to a paper set to appear Friday (8/15) in the journal Science, the downward spiral started when people first began killing off reef-frequenting large fish, turtles, seals and other ...Dual discoveries in genetic processing improve accuracy of genome information
...ced on every organ," said Reenan. The phylogenetic signatures are identical sequences of genetic coding found in each species studied, serving as markers corresponding to specific genes targeted for A-to-I RNA editing. The identical presence in both species suggests that the editing site arose some time ago ev...Physics tip sheet #36 - July 30, 2003
...both neutrino masses and dark energy leave similar signatures in the matter distribution of the universe, and a ... gravitational lensing experiments to measure both signatures simultaneously. Journal article: <A HREF="http://link.aps.org/abstract/PRL/v91/e041301">http...Lead-based paint is poisoning albatross chicks at Midway Atoll National Wildlife Refuge
...hey found a strong correlation between the isotope signatures in a chick's blood and the signatures in paint chips from its nest. There was no correlation with isotope signatures from soil samples. Le...U-M scientists find cancer's genetic core: 67 genes universally activated in human cancer
...chnology, more than 200 studies of gene expression signatures in human cancers have been published. They include millions of data points from thousands of experiments stored on different technology platforms. Most cancer biologists don't have the bioinformatics expertise to access the data, so they have been un...Pancreatic cancer genes ID'd in most accurate study to date
...to preserve fragile molecules that act as telltale signatures for genes that are "turned on" or expressed. Unlike other scientists, the U-M team was able to distinguish genes involved in cancer from those involved in a chronic inflammatory disease, pancreatitis, that's often mistaken for cancer. Both diseases p...With government nod, gene therapy pioneered at UNC is given to children with rare disorder
...hromosomal DNA that has all the 'start' and 'stop' signatures and other information the cell needs to make the appropriate protein; in this case, the missing enzyme."While a cure is highly unlikely, researchers hope disease progression can be slowed, if not halted. Two weeks following surgery, the children are ...Study shows molecular analysis of early breast cancer lesions may be key to choosing best treatment
...ods for diagnosing cancer based on gene expression signatures with currently accepted and proven pathological cl...technologies can generate accurate gene expression signatures that precisely characterize tumor cells and that these signatures can be used to determine the molec...Bone marrow stem cells are a source of insulin-producing cells
...ecreted insulin in response to glucose, one of the signatures of pancreatic beta cells, and exhibited electrical activity and other properties of beta cells. Moreover, a second set of experiments showed that these bone marrow derived cells were unlikely to be a result of cells fusing together. Some resea...