First clinical study of new pediatric croup vaccine shows safety, tolerability in adults
...dition of the world's most successful vaccine, the smallpox vaccine, said Julia Hurwitz, Ph.D. member of the department of Immunology. "The smallpox vaccine was based on the cowpox virus, which caused only limited skin infection in healthy humans," ...Physics gravity model applicable to disease spread
... spread of new or reemergent diseases like SARS or smallpox is essential in controlling disease epidemics, but horse-and-buggy concepts of how diseases spread have been supplanted by 21st-century realities. "In the past, one expected the spread of disease to be based on distance, and the closest town would b...Children's Hospital Boston receives more than $10 million to help make smallpox vaccine safer
...udy a potentially life-threatening complication of smallpox immunization known as eczema vaccinatum (EV). The...al is to reduce the risk of EV and develop a safer smallpox vaccine. EV is a severe skin infection caused by vaccinia, the live virus used in the smallpox vacci...Report outlines steps needed to lessen smallpox threat
The best bet for averting the deadly spread of smallpox following release of the virus by terrorists may r...sing need for novel drugs to prevent the spread of smallpox if it were to be used as a bioterror agent, Harrison said that the group's top recommendation was th...Susceptibility of mice to mousepox offers promise of smallpox protection
...easing numbers of persons being vaccinated against smallpox with the vaccinia virus--primarily health professi...usepox model has proven a useful tool for studying smallpox biology because of the ample mouse gene knockouts available. Karupiah also emphasizes the importance...Study suggests double punch could more efficiently kill viruses
... colleagues used vaccinia virus - the virus in the smallpox vaccine - and influenza A virus, in a mouse model to further investigate how the cross-priming pathway works. The team found that it is not peptides that are shared with recipient cells, but rather full-length, intact proteins. And, whereas, the prev...The search for a safer smallpox vaccine: New data released on promising candidate
ST. LOUIS -- When used as an aerosolized weapon, smallpox could be controlled by a new vaccine under study a...lington, Va. The research tested the efficacy of a smallpox vaccine candidate known as LC16m8. The research conducted at Saint Louis University by Buller and hi...NIH awards $20.7 million to make smallpox vaccine safer
...sortium of academic medical centers trying to make smallpox vaccines safer for millions of people with atopic ...titis and people who live with them do not receive smallpox vaccines because atopic dermatitis patients and former patients face an increased risk of developing...First time in the U.S.: Saint Louis University tests third-generation vaccine against smallpox
... - Not everybody can safely be vaccinated against smallpox using the current FDA-approved vaccine. Scientists hope another study vaccine, now undergoing its first testing in the United States at Saint Louis University, will give a choice to people who can't be given the current vaccine, known as Dryvax. "The...Researchers begin study to protect against anthrax
... the Rochester area, showed that a diluted form of smallpox vaccine is just as effective as a full dose in protecting against the disease. And last year Treanor led a national team of scientists looking at how a booster shot affects the protection of people who have previously been vaccinated against smallpox...Experimental smallpox DNA vaccine protects primates from lethal monkeypox
...scientists have shown that a DNA-based vaccine for smallpox can protect nonhuman primates from monkeypox, a disease that resembles smallpox in humans. The study, performed at the U.S. Army Medical Research Institute of Infectious Diseases ...Tips from the Journals of the American Society for Microbiology
... SMALLPOX A DNA based vaccine may protect against smallpox say researchers from the United States Army Medica...dae, including VACV (the virus used in the current smallpox vaccine), monkeypox virus (MPOV), and variola virus (the virus that causes smallpox), are highly sim...Gene with key role in replicating pox viruses also halts inflammation
...rrorism by means of the deliberate introduction of smallpox have spawned renewed interest in new, safer vaccin...e vaccinia virus, but while this tamer relative of smallpox normally doesn't cause disease, complications, including death, are possible especially among immune...Experimental smallpox vaccine protects against monkeypox in nonhuman primates
...otential safer replacement for the licensed Dryvax smallpox vaccine, have shown that MVA elicits an immune res...eapon has led to the production and stockpiling of smallpox vaccine and the immunization of some healthcare workers. Because Variola no longer occurs naturally,...Device detects, traps and deactivates airborne viruses and bacteria
...ting airborne bioagents and bioweapons such as the smallpox virus, anthrax and ricin, and also in routine indo...lysts to capture and destroy bioagents such as the smallpox virus. "When the aerosol particles come into the device they are charged and trapped in an electrica...VaxGen reports Phase I clinical trial results of anthrax vaccine candidate
...is developing preventive vaccines against anthrax, smallpox and plague and an anthrax monoclonal antibody through an alliance with Avanir Pharmaceuticals. VaxGen also is the largest shareholder in Celltrion, Inc., a joint venture formed to build operations for the manufacture of biopharmaceutical products, i...Surveillance and containment would be effective intervention against deliberate smallpox attack
...y 14. Although mass vaccination during or before a smallpox attack would result in fewer cases and deaths than...nd death would offset the slightly lower number of smallpox illnesses and deaths, especially since no one knows when or where an intentional release of smallpox...Planning effective bioterror responses
... in surveillance systems, according to Stoto. If a smallpox outbreak were to occur, how many people in contact...ults, from a simulation of the possible paths of a smallpox epidemic that initially infects 500 people, in a study submitted to a peer-reviewed journal. If anth...Finding may help eczema sufferers tolerate smallpox vaccine
... they are at high risk of adverse reactions to the smallpox vaccine, report scientists in the February Journal...e with the skin condition to be vaccinated against smallpox without breaking out in a potentially deadly rash. According to co-investigator Richard L. Gallo, M...Smallpox in 50-year-old tissues detected by integrated diagnostics approach
...n. Taken together, these results suggested primary smallpox disease. To add confidence to this presumptive diagnosis, the team extracted DNA from tissue sections and tested it using TaqMan assays. These assays are based on a process called polymerase chain reaction, or PCR, that can be monitored in real ti...