Tag: "sought" at biology news

Researchers describe atomic-size 'sorter' that performs vital cellular function

...ng QT in a small number of people. Even the highly sought antibiotic, Cipro, has demonstrated some long QT effects. "Its hard to tolerate even one in a thousand instances of a drug-induced, potentially fatal conduction abnormality," says MacKinnon. "But its hard also to test for because theres some unknown...

Researchers discover secrets of Anthrax's killer toxin

...ing cells." In the second study, other researchers sought to learn how the LF part of anthrax toxin attaches to its target molecule inside of a person's cells. After entering cells, LF locates a protein called MAPKK and chews off one of its ends, preventing it from working. Because MAPKK is a key molecula...

African wildlife databases benefit animal conservation efforts

... for the international wildlife community. Namibia sought help from Chicagos Brookfield Zoo and the UI in 1994. A collaborative program, which primarily focuses on the 8,600-square-mile Etosha National Park, has led to an unprecedented database of demographics, habitats, diseases, genetics and reproductive...

Scientists identify chromosome location of genes associated with long life

...sease -- or avoid them altogether. The researchers sought the characteristics to explain the disease-resistance and survival advantage characteristic of a group of individuals age 98 and older. Because centenarians are hard to find, they opened their search globally. In the process of taking medical histori...

How brain cells remember their birth order

...irth order. In their experiments, the scientists sought to understand in what order the fly neuroblasts expressed four transcription factors that were good candidates for regulating the birth order of daughter cells. These transcription factor genes are called hunchback, Krppel, pdm and castor. We first ...

Integrins and signaling in psoriasis

...ies that resemble psoriasis, Haase et al. have now sought evidence of signaling abnormalities that might explain the effect of these receptors. The authors focus on the MAP kinase pathway, which mediates integrin effects on basal cell growth. They show here that they can bypass a requirement for high integ...

Age at first drink: What does it really mean?

...eveloping alcoholism. Some prevention efforts have sought to decrease alcoholism risk by delaying age at first drink (AFD). An early AFD may in fact be one of several behaviors that comprise 'behavioral undercontrol.' Parents with an early AFD have children at increased risk for behavioral undercontrol. Pr...

Russian, PNNL scientists advance US seed production, oil remediation

...ng and production company based in Pomeroy, Wash., sought technical expertise for its turf grass seed operation from the Department of Energy's Pacific Northwest National Laboratory. Laboratory scientists linked them with Russian scientists who had developed a plant growth stimulator and an oil remediation ...

Component of fly saliva makes promising Leishmaniasis vaccine

...edicine, Dr. Ribeiro directed a research team that sought to use this information to produce a novel vaccine against the disease. Jesus Valenzuela, Ph.D., Dr. Ribeiro and colleagues examined saliva from the sand fly carrier of Leishmania major, a parasite species that causes cutaneous leishmaniasis. The r...

Staph bacteria are prolific gene swappers, researchers show

...vive different environments, and Dr. Musser's team sought to learn how genes have been exchanged between strains. In the study reported in today's online edition of the Proceedings of the National Academy of Sciences, first author Ross Fitzgerald, Ph.D., and colleagues from Dr. Musser's lab compared the ge...

New study shows normal-looking clones may be abnormal

...ch's laboratory and Ryuzo Yanagimachi's laboratory sought to examine the mechanisms underlying poor survival and gross overgrowth in cloned animals. They made mouse clones from embryonic stem (ES) cells and monitored the activity of imprinted genesdevelopmental genes that are controlled by special tags that...

Rutgers-led researchers discover new photosynthetic bacteria that appear to be significant component of ocean's carbon cycle

...pedition last year, Kolber and his team originally sought to verify the presence of the strange bacteria at hydrothermal vents on the ocean floor in the northeast Pacific. "It was postulated that the light generated by the superheated water in thermal vents and chemical processes taking pla...

Undergrad's digital model of amoeba helps scientists study human cells

...g one-dimensional model of Dictyostelium. Iglesias sought a student to expand upon this research by devising a more detailed two-dimensional version, using new software called Virtual Cell. "I just jumped at the opportunity," Kim said. She learned how to use the challenging software during an internship las...

Welch honors Kornberg for insights into DNA transcription

...low at Cambridge University in the early 1970s, he sought to apply X-ray diffraction and a novel variant of the electron diffraction technique developed by Aaron Klug to the structure of chromatin, the material from which chromosomes are made. This work led to his discovery of the nucleosome. After return...

Treating acne with antibiotics leads to resistance

... resistance in other bacteria, and the researchers sought to determine if that was also occurring in P. acnes. In the study presented at the ASM Meeting, bacterial skin samples were taken from 99 patients being treated for acne with antibiotics and 30 control subjects who were not receiving antibiotic trea...

Color vision out of the corner of the eye

...to a much higher degree. Such mechanisms have been sought anatomically but not found. A critical test betw...nd from the State College of Optometry in New York sought red-green opponency in far peripheral retina using detailed quantitative methods. The results were u...

Prairie fire--UIC-style

...vation group, the Openlands Project. It, in turn, sought backers to raise $200,000 to buy the land. Half was donated by a charitable foundation, the Chicago Community Trust. After securing matching federal funds and pledging additional money for improvements, the University of Illinois at Chicago took ov...

The masculinization of the X chromosome: many genes for early male sperm production reside on the X chromosome

...on for Biomedical Research, in San Antonio, Texas, sought to study the genetic underpinnings of spermatogonia-stem cells in the testes that give rise to sperm. Spermatogonia are "the mother of all sperm cells," but unlike other stem cells, such as blood stem cells, which have been the subject of intense stu...

Federal government makes final call for data, public comment before writing new report on cancer-causing substances

... Institute of Environmental Health Sciences, today sought final public comments and data on these and several other substances and exposures before recommending whether to list them as human carcinogens in the federal government's tenth and newest Report on Carcinogens. Comments will be accepted for 60 da...

Growing neurons use silencing mechanism to avoid disastrous tug-of-war

... the silencing effect. Next, the scientists sought to rule out the possibility that Slit might be binding to netrin directly. They created “chimeric” Robo and DCC receptors that replaced the Slit or netrin attachment domains with a domain triggered by a different protein, called HGF. W...

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