NIH Team Discovers Endocrine Tumor Gene
...rited from an unaffected parent, and to identify a specific region that might harbor the sought-after gene. "We were able to look at the tissue sample and say 'Here's the DNA segment to search'," says Dr. Emmert-Buck of NCI. Scientists could then analyze the DNA. Drs. Collins and Chandrasekharappa ...Biosensor Is A Model For Widespread Testing Of Chemicals, Molecules
...ate chemosensitive surfaces that respond in a very specific mannerto whatever it is we are interested in, whether checking PCBs in the environmentor for sugar levels in the blood of diabetics," Hellinga said. "Wewill have to keep engineering the protein so that it will behave itself,but it is quite doable."...Researchers Find Production Point Of Key Protein In Fragile X Syndrome
...at determines sex -- when cells are cultured under specific conditions.The gene was found in 1969, but its relationship to mental retardation wasnot understood. It was sequenced and named the Fragile X Mental RetardationGene in 1991, but its mechanisms remained a mystery. The Fragile X Mental Retardation Gen...Everyday Technology Underlies First DNA Computer Logic Gates
...-- actually tiny DNA processing centers -- detect specific fragments of the genetic blueprint as input, then splice together the fragments to form a single output. For instance, a genetic And gate links two DNA inputs by chemically binding them so they're locked in an end-to-end orientation -- much as ...Ozone 'Chat Room' Provides Real-Time Air-Quality Research
...ty of interacting people without having to be at a specific place," Husar says. "This is a dream come true for an environmental engineer -- to express your viewpoints and research and participate in something that has substantial meaning for the American public, all the while using our skills and resources f...Calorie Restriction Reduces Age-Related Muscle Loss
...ach mitochondrion. Finally, they examinedfibers in specific rat muscles. Researchers examined muscle tissue from old rats on unrestricteddiets, and moderately (35 percent) and highly (50 percent) restricteddiets. Young rats on unrestricted diets also were included in the study. Analysis of the tissue showed...Stopping "Cellular Suicide" Could Boost Production In Biotech Labs
...umblingblock, Betenbaughinstalls "stop signals" at specific points along a cell's roadtowardself-destruction. To find these signals, he works withresearchers led by <a href="http://www.sph.jhu.edu/Departments/MMI/faculty/hardwick.htm">J. Marie Hardwick , an associateprofessor of molecular microbiolog......pported by thescience, and if it doesn't address a specific risk, what is the basis for therule?," concluded Daniel Haley, president of Haley & Associates law firm, duringthe EPA workshop. Despite these grave concerns, the EPA intends to finalize its plant-pesticides policy by the end of 1997....Coming Extinction Of One Of UK's Most Minuscule Plants Yields Information On Climate Change
...he seed bank in the soil. It appears to have very specific ecological requirements and grows on open basalt gravel terraces where there is little competition from other species. It is a small member of the Dock family with large specimens being 4 cms high with tiny greenish flowers about 3 mm across. Note ......eases -- or themRNAs associated with resistance to specific drugs. In fact, an EGS already hasproved effectiv... way to restore drug sensitivity,regardless of the specific drug or infection involved, is to find the bestmethod of getting EGSs inside bacteria, Professor Alt...... proteins -- into the inclusions? And what are the specific links betweenthe aggregates and neuronal dysfunction and death? Potential therapies for thediseases could be pursued along each of these lines of inquiry. The lead author on the Neuron paper is former Penn research associateHenry L. Paulson, ...Newly Discovered Human Protein Provides Important Target For Cancer Therapy
...sing yeast. They created novel yeast mutants with specific defects in theirability to replicate telomeres. Shortly thereafter, both the Whiteheadresearchers and a team led by Drs. Joachim Lingner and Thomas Cech of theUniversity of Colorado, Boulder, and Dr. Victoria Lundblad of the Baylor Collegeof Medici...Wild Plant Genes Increase Food Production
... of rice and tomato plant varieties and looked for specific loci or genes -- known as the Quantitative Trait Locus, or QTL -- that would tend to boost production. Before the availability of molecular markers, breeders had no way of finding the genes from the wild species because there was no way to identify t...One Chimp Can Perceive States Of Awareness In Others
...chimpanzee could tell if another was ignorant of a specific situation, inthis case, of a threat or a reward. ...en said that thesewere generalized warnings -- not specific ones. These experiments removedmost of the variables that exist in the wild and tested if one chimp ...MGH-Led Team Finds Gene For Crippling Neurologic Disorder
..., isunique," Ozelius says. "It suggests that this specific area of the gene and ofthe protein it codes for must be crucial to its function, which is stillunknown." The researchers also found that the DYT1 protein has significant similarities to the heat-shock proteins and proteases. Found in virtually all ...Mutant Gene Not Sole Explanation For Hiv Non-Progression
...t cells. HIV-infected people with a specific mutation in one of their two copies...ors five years ago to determine the specific factors that protect these people from HIV disease progression. Soon after the discov...NIH Office Of Dietary Supplements Expands Research Support
...mine if antioxidants can prevent the production of specific toxic compounds found in the lens of the diabetic eye. The ODS will cosponsor with the National Institute of Child Health and Human Development a project at the Baylor College of Medicine in Houston, Texas to measure the benefits of intestinal supple...Imaging Studies Illuminate Brain's Response To Cocaine
...der of this research, says, "These studies suggest specific brain areas thatmight be targeted in developing new medications to either block individualaspects of cocaine's effects - like the rush versus the craving experience - oras broader treatments for cocaine abuse and addiction." Additional funding forthi...Further Proof That An Altered Rb-2/p130 Gene Leads To Lung Cancer
...ns begin treatments earlier, and tailor them to specific patients, depending on how aggressive the cance... disease, and ultimately design alternative and specific therapeutic strategies. This can be done only by understanding how this mechanism of cancer devel...