Tag: "spinal" at biology news

UT Southwestern scientists explain how the injured brain remodels itself

... medical therapies to enhance an injured brains or spinal cords restorative capabilities. In the long term, Kernie said, the current results also raise hopes of developing new or more effective human therapies using embryonic or adult stem cells for reducing or overcoming paralysis and other severe brain an...

New Phase 2 study shows ankylosing spondylitis patients respond to ENBREL (etanercept)

...measures (duration of morning stiffness, nocturnal spinal pain, a functional index (BASFI), patient global assessment and swollen joint score). Eligible patients fulfilled the modified New York clinical criteria for ankylosing spondylitis, and were required to have evidence of active spondylitis, which was...

Stanford, UCSF researchers home in on key gene in multiple sclerosis progression

...issue. This patchy loss of myelin in the brain and spinal cord slows communication between nerve cells, leading to symptoms such as muscle spasms, weakness, sensory deficits and visual disturbances. Two important pieces of evidence presented in the paper indicate that in an experimental model of MS, ...

Stanford engineer studies neural prosthetics

...d arm. Damage to any part of that chain, such as a spinal injury, stroke or neurodegenerative disease, can make even the simplest tasks impossible. In a new study, Stanford engineer Krishna Shenoy and a group of researchers at Caltech have shown that at least some links in that chain can be dramatically byp...

Stem cells, forged into neurons, show promise for brain repair

...at populate the different regions of the brain and spinal cord. The work represents a critical step toward ... neural cells and tissue to repair everything from spinal cord injuries to the ravages of Parkinson's disease. The new work was conducted largely at the WiCel...

Delayed treatment of spinal cord injury may improve recovery

... an experimental therapy several weeks after their spinal cords were severed showed dramatically greater reg...ggests that the window of opportunity for treating spinal cord injury may be wider than previously anticipated. The researchers used a combination therapy of...

Immunotherapy treatment shows dramatic results for rare neurological disorder

... an autoimmune response gone awry in the brain and spinal cord. SPS is characterized by fluctuating muscle rigidity in the trunk and limbs and a heightened sensitivity to stimuli such as noise, touch, and emotional distress that can set off muscular spasms. People with SPS are often too disabled to walk or ...

Researchers find gene involved in pain relief

...eased production of dynorphin in the region of the spinal cord involved in transmitting and controlling pain messages. The mice, they discovered, had decreased sensitivity to acute, inflammatory and neuropathic pain. "The attenuated pain response was evident for all types of pain in all types of tissue tes...

Research may lead to jump-starting damaged nerve cells

... cells, and suggests possible avenues for treating spinal cord injuries, Parkinsons disease and amyotrophic ...ase. University of Houston scientists studying how spinal nerve cells in chicken embryos develop and function have found that chemicals called growth factors ...

Recovery from spinal cord injury seen in mice when scarring is minimized

PHILADELPHIA - Severe injury to the spinal cord can lead to devastating loss of function, and...e ways to promote regeneration of the cells in the spinal cord or otherwise encourage a restoration of function following injury? A new study conducted in mi...

New transgenic rat model of ALS expands research possibilities

...ll, for example, for reliable infusions into their spinal cords, the direction research on stem cell treatment is heading." Scientists at Wyeth-Ayerst engineered the rats to carry an abnormal human gene for superoxide dismutase (SOD1), an enzyme that normally breaks down free radicals, highly reactive molec...

Scientists prove mature adult cells can be cloned

...may be used to treat diseases, such as diabetes or spinal cord injury, without the complications of organ rejection. Using Immune Cells to Clone Mice Scientists have known for sometime that cloning using ES cells is much more efficient than using adult cells, probably 10 fold more efficient. This makes sens...

Keck Foundation awards $750,000 grant to Northeastern University to fund 3D fusion microscope

...velopmental processes relevant to the treatment of spinal cord injuries. "The combination of instruments on ...at establish connections between the brain and the spinal cord." The affiliation of this instrument with CenSSIS provides a unique environment for biological ...

New mouse model enables studies of heart, brain and spinal cord

...in major body systems such as the heart, brain and spinal cord, has been developed by Medical College of Geo...s involved in not only the heart but the brain and spinal cord, skin and hearing. It even is implicated in some cancers, including melanoma and the more rare ...

UNC neuroscience center awarded $1.7 million for nerve growth and regeneration studies

...ystem, it will re-grow. However, if you damage the spinal cord, no growth whatsoever occurs."Some of his gro...ble to exploit them to promote regeneration of the spinal cord."...

Neural stem cells move to damaged areas of brain after injury

...malian adult central nervous system the brain and spinal cord was incapable of generating new neurons from adult stem cells, a process known as neurogenesis. But now scientists know that precursor cells in a part of the brain called the subventricular zone or SVZ continue to produce new neurons throughou...

Putting microRNAs in their place

...or Neurons protein, which, when mutated results in spinal muscular atrophy, the second most common childhood neuromuscular disorder. This finding of shared components between the SMN complex and the miRNP suggests a possible link between the pathway of miRNA activity and the progression of this common disea...

Experimental Biology 2002, Translating the Genome

...utic potential of different types of stem cells in spinal cord injury, how sex hormones affect the developing brain, the effect on gastrointestinal disease of the enteric nervous system (the nervous system that drives the GI system) and its effect on gut diseases, and mechanisms of craniofacial bone growth....

Undergrad probes regeneration of nerve cell branches

...er wholly or partially located in the brain or the spinal cord could not regenerate after damage to their br...ers involving nerve degeneration or injury, or for spinal cord injuries....

UCSF prion finding in mice leads team to urge similar study in cattle

...at prions only accumulate at high levels in brain, spinal cord and lymphatic tissue. As a result, Great Brit...countries of the European Union have banned brain, spinal cord and lymphatic tissues from the human food supply.2. This measure is the most extreme step these...

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