Tag: "spleen" at biology news
NIAID Doctor Successfully Treats Longest Case Of Malaria Infection On Record
...ved after she discontinued treatment, the enlarged spleen
and other signs of an obscure systemic...r. Vinetz suspected that her persistently enlarged spleen
and former bout of recurrent fever could be due to malaria. Although the four types of h...
Three-Day Treatment Cures Decades-Old Case Of Malaria
... minted young medical graduate to have an enlarged spleen
during a routine physical in a rural clinic. ... Parasitic Diseases, suspected the fever and large spleen
might be caused by malaria. In only three days, using five doses of anti-malaria medicine, she was c...
RNA-Dendritic Cell Combo Shows Promise As A Universal Cancer Vaccine
...s known as"killer T" cells which move out from the spleen
and lymph nodes to attack theinvader. Cancer cells also produce a variety of atypical proteins, Gilboa said,but tumor cells have evolved ways of effectively hiding these proteins fromsurveying dendritic cells. In this way, cancer is virtually...
Molecular Defect Could Be Mysterious Cause Of Blood Disorder
...production occurs outside of the bone marrow inthe spleen
and liver. Polycythemia vera is marked by a great increase in the number of redcells in the blood, resulting in headaches and potentially fatal blood clots. It is usually treated by a modern form of bloodletting, although more severecases m...
Chelation Therapy May Alter Immune System
...s of leadexposure, such as altered body weight and spleen
weight in rat pups andincreased levels of tumor necrosis factor (TNF) and interlukin-4 (IL-4). Elevated levels of TNF and IL-4 are generally regarded as signs of amalfunctioning immune system. But the offspring whose mothers had received chelation...
Scientists Discover Protein In Mammals Tuned To Respond To What May Be Hottest Temperature Our Nerves Can Detect
...evidence of it in the brain and spinal cord, inthe spleen
and intestines. Clearly, in these sites it must be responding tosomething other than temperature." Whatever the full function of VRL-1, its discovery holds promise for betterunderstanding pain and developing drugs to block pain, Julius said."The numb...
Learning how organs tell left from right
...perfect symmetry throughout the body. The heartand spleen
normally reside on the left side and the liver and gallbladder are onthe right. Furthermore, the organs themselves are asymmetrical. Understanding how genes control the shape and spatial orientation of organsis one of the goals of developmental biol...
Virtual reality tool quantifies physics of a doctor's touch
..."but we can't really tell why -- is it a shattered spleen
or a lacerated liver? A database with information in it that could tell us that, just based on the consistency of what the physician is feeling, could allow the surgeons to go right into the operating room without having to obtain a CAT scan. It co...
Researchers decipher chemical 'cross talk' that determines survival of immunecells
...f autoimmune disorders. In key experiments using spleen
cells from mice Jamieson and Yamamoto showed that a well-studied gene called Ras triggers the pathway that rescues T cells from GR death signals. "Ras acts as a molecular switch at the nexus of several incoming signals and, in turn, activates a net...
Carolina scientists the first to identify and purify liver stem cells
...of liver cells would be injected into the liver or spleen
of patients with liver failure and should reconstitute the patient's liver functions. "Thus, each donated liver can be used to treat many patients, and the surgical procedures will be much safer and easier on the patient and much more economical th...
Scientists use new technique to pinpoint key gene in infectious fungus
...a. It also can spread from the lungs to the liver, spleen
and other organs, causing serious illness or death. Histoplasma capsulatum, the fungus that causes histoplasmosis, lives in soil. When its spores are inhaled, the higher temperatures in the respiratory system convert it to a yeast, which is taken in...
Infections may trigger autoimmunity via rare, but normal process
...he first-wave infection response congregate in the spleen
and in lymph nodes, joining dendritic cells and T cells to form structures known as germinal centers. (One such center is pictured on the cover of the December 18 Journal of Experimental Medicine.) Here, the B cells enter into a process called hyperm...
New study: genetically engineered enzyme boosts treatment for rare children's illness
...they had more energy and their oversized liver and spleen
shrank dramatically. Six patients we treated prior to puberty also showed an increased growth rate." MPS 1 is a recessive disorder with an estimated incidence of one in 100,000. About one in every 200 to 300 people in the United States may carry the...
Zebrafish could become genetics 'lab rat' of choice
...ined in the presence of cells from a rainbow trout spleen
cell line, RTS34st, are able toproduce germ line c...um and disappeared by 5 days in the absence of the spleen
cells. The RTS34st cells also inhibited melanocyte and neuronal cell differentiation in the embryo ...
New reserach shows promise in conquering ulcer-causing H. pylori
...they were treated with healthy spleen
cells. After that treatment, no ...re injected with splenocytes - spleen
cells taken from healthy mice. Spleen cells normally help the blood filter toxin...
FDA approves new treatment, Campath , humanized monoclonal antibody, for patients with B-cell chronic lymphocytic leukemia
...ion and enlargement of the lymph nodes, liver, and spleen
may occur. Patients with B-CLL may suffer from disease-related symptoms such as fatigue, bone pain, night sweats, and decreased appetite and weight loss. Campath appears to work by targeting the CD52+ antigen on the malignant lymphocytes. Campa...
Gene therapy for arthritis
...targeting is cru-cial,since the DCs must reach the spleen
if they are to have their desired effect on T-cell...eads to the most efficient targeting of DCs to the spleen
and confersthe greatest protection from arthritis....
Copper is crucial for embryonic deveopment, say U-M scientists
...ion, reduced copper accumulation in both brain and spleen
from Ctr1 heterozygous mice indicates that two functional copies of Ctr1 are critical for maintaining normal copper balance." Copper deprivation is particularly dangerous for children and infants, according to Thiele. Children born with a genetic co...
Researchers identify potential for prenatal gene therapy
... disorders, GFP expression was present in both the spleen
and bone marrow, indicating that Sleeping Beauty can localize to hematopoietic organs in vivo. Details of Mortari's presenation: Time: Monday, December 10, 2001, 10:30 a.m. EST Session name: Vector Development and Assessment Title: In Utero...
Whales get the bends
...ary shells, can damage the heart, lungs, liver and spleen
of dolphins, as well as the most sensitive organ, the ear. She exposed the carcasses of beached dolphins to controlled underwater blasts. "We're seeing classic symptoms of blast lung and gut haemorrhage," she told a meeting of the Society for Marine...
1 2 3