Cigarette smoke causes breaks in DNA and defects to a cell's chromosomes, Pitt study finds
...ention has been given to how smoke affects genomic stability of cells. In laboratory studies using human fibroblasts, common cells found in connective tissue, William S. Saunders, Ph.D., and colleagues discovered that exposure to even a small amount of cigarette smoke condensate equal to about 1/25 of a cigar......al models of cancer, to explore its effectiveness, stability and distribution in vivo....Battle between bubbles might have started evolution
...esized cell membranes or otherwise influenced cell stability or division. The researchers, led by Howard Hughes Medical Institute investigator Jack W. Szostak, published their findings in the September 3, 2004, issue of the journal Science. Szostak and first author Irene Chen, both from Massachusetts Genera...Infants sighs may 'reset' breathing regulation mechanism as well as help lungs develop
...sigh, though since its role is to assure long-term stability of breathing control, this makes sense. But the short-term memory, which controls breath-to-breath variability, is affected by the sigh, and seems to prepare the breathing "system" for any changes in the environment, such as noise, movement, or wakin...Protein vaccine fully protects mice from lethal aerosol challenge with ricin toxin
...e safety and efficacy of a vaccine depend upon the stability of its formulation. The new vaccine candidate, called RTA 1-33/44-198, is a fragment of the ricin A-chain that has been modified to eliminate the toxic enzymatic property of RTA, increase protein stability, and maintain its ability to elicit a pr...UCI study reveals gene linked to breast cancer can suppress tumors
...ed with repairing DNA damage, promoting chromosome stability and regulating cell growth activity, but this study has identified a novel and potentially important role as a tumor suppressor. The researchers only studied the tumor-suppressing role of BRCA1 in breast cancer. Mahnaz Razandi and Ali Pedram of UCI a...Newly designed nanoparticle quantum dots simultaneously target and image prostate tumors in mice
...mer appears to lend a great deal of protection and stability to the quantum dot probes inside the animals," Dr....range of pH and salt conditions and maintain their stability even after treatment with hydrochloric acid." Quantum dots are more brightly fluorescent than tradit...Reading hexametric rhyme supports cardiac synchronization, especially after a heart attack
...ough poetry, of regulatory processes that maintain stability and coherence between different physiological func...nderstanding of regulatory processes that maintain stability and coherence between different physiological functions since cardiorespiratory interaction seems to...Sponge substance works well with yew derivative to thwart cancer cell proliferation
...ynamic instability by 24 percent. By altering the stability dynamics of microtubules, paclitaxel and discodermolide limit cancer cells ability to duplicate DNA and divide. The cells are stuck in a pre-division stage of the cell cycle called G2/M. Cancer cells that are restricted to the pre-division stage of t...Carnivore extinction risk determined more by biology than human population density, says study
...t greater danger later: "Arguably, maintaining the stability of particularly susceptible species before they become threatened could be more cost-effective in the long term than postdecline attempts to rescue them from the brink of extinction," they conclude. They suggest pre-emptive action including the estab...Genetic model for devastating form of paraplegia suggests new treatments
...ures, continually growing and shrinking, and their stability is closely regulated by a number of associated pro...s found that specific drugs that alter microtubule stability remedy the defects that occur in synaptic function as a result of changes in spastin levels. In both...A genetic model for hereditary spastic paraplegia (HSP) disease
...ractions. Microtubules grow and shrink, and their stability at a given time and place can be regulated by othe...s found that specific drugs that alter microtubule stability appear to remedy defects that occur in synaptic function as a result of changes in neuronal spastin ...Releasing pet fish into the wrong ocean proves a diaster
...water picked up and discarded by ships to maintain stability as a cause for the introduction of exotic fish. "Their home ranges do not overlap with shipping routes," Semmens says. Most of the exotic fish have yet to establish a viable population, but scientists are worried about the ecological and economic im...Hopkins to found first center for comprehensive study of epigenetics
..."The IHF collaboration will let us really test the stability of epigenetics and the passage of those marks from parents to child, perhaps even over successive generations." At the heart of the center's work is epigenetics' importance in proper cell function and in development. One example of epigenetics is "i...'Plants for the future': A European vision for plant biotechnology towards 2025
..., harvestability, processability and environmental stability to be created, Novel public- private partnerships will also need to be created to develop these products and bring them to market. "EPSO and EuropaBio will develop this Technology Platform in the framework of an EU supported project that started on ...Scientists raise awareness of need for sound science in age of fad diets
...on, will address the impact of fad diets on market stability and agriculture production. WHERE: 2226 Rayburn House Office Building WHEN: Thursday, June 17th at 12 noon Representing 130,000 individual scientists from 21 scientific organizations, CoFARM is a broadly based coalition united by a commitme...New insights on sirtuins, involved in gene expression and aging
...ctivate sirtuins, perhaps we could promote genomic stability and decrease cancer as well as other aging-related problems." Marmorstein's research team has been focusing on the molecular details of how sirtuins work. Sirtuins are a family of enzymes, proteins that facilitate chemical reactions that involve conv...Brace therapy for osteoarthrisis, legal issues in TBI research, prosthetic fitting
...FOS outperformed axillary crutches for comfort and stability on slippery surfaces, uneven surfaces, and stairs....ings in an existing method for evaluating postural stability by including platform incline and ground impact. Ankle moment and ankle stiffness for standing are a...Keck Futures Initiative announces grant recipients
...nt for high performance function while maintaining stability to the process that created them (random variation) and adaptability to manage in an unpredictable and ever-changing world. PAMELA SILVER Harvard Medical School and the Dana-Farber Cancer Institute, Boston BIOLOGICAL PATTERN FORMATION VIA ......kes live sampling much less invasive." To test the stability of the DNA samples, the researchers filed cards containing samples of bird blood in a box that they kept in a laboratory cupboard. Four years later, they successfully amplified DNA from these cards, demonstrating that, even though the temperature flu...