Pack-MULEs are toting a new look at plant evolution
...out tantalizing possibilities that could turn some standard methodology on its ear. "Even a lot of my colleagues say they don't understand my article," says Jiang, who one month ago left a post doc at the University of Georgia to take a faculty position at Michigan State University's horticulture department...Phase II trials of second-generation antisense cancer drug planned following successful early study
...rvival mechanism and enhances the effectiveness of standard chemotherapy, radiation and hormone therapy. Twen...esign, looking at response rates from OGX-011 plus standard chemotherapy in patients with metastatic hormone refractory prostate, breast and lung cancer. Phase ...Trial shows which brain cancer patients benefit from temozolomide
...omide. Temozolomide would now certainly become the standard treatment for those patients whose tests predict that they would benefit from the drug. Dr. Hegi said these results were important not only for patients who were likely to benefit, but also for those that were not. Even though the drug was well toler...Flexible pain relief with morphine-free poppy
...we found behaved differently in Norman compared to standard morphine producing poppies and were consistently associated with the blockage in morphine synthesis and with the accumulation of thebaine and oripavine," Dr Larkin says. "Understanding the genes responsible for the production of morphine, thebaine a...March of Dimes statement on newborn screening report
...th and Human Services to accept them as a national standard for newborn screening. Based on the findings of this report, the March of Dimes will expand our policy on newborn screening as follows: We will urge every state to screen every baby for at least the 30 disorders listed in the ACMG report. Th...Experimental drug shown to block mutant protein causing blood disease
..., they are associated with fewer side effects than standard cancer drugs. In the study, mice with MPD that were treated with the oral compound PKC412 significantly outlived those given a placebo. When tested in a single patient, a 52-year-old woman with MPD, the drug reduced her dangerously high white blood c...US investment firm gives away Rhode Island-sized lands in Chile
... global conservation. Goldman Sachs has set a new standard for the private sector's commitment to the natural world, and deserves tremendous credit for their imagination and resolve that these lands and their wildlife should be protected now and forever." Lands That Awed Darwin The Chilean lands transferr...A liking for sweets, combined with novelty seeking, may predict alcoholism
...the Tridimensional Personality Questionnaire and a standard sweet-taste test, and evaluated for paternal family history of alcoholism. The main finding of this study is that two independent and presumably heritable traits, such as sweet liking and high novelty seeking, separately were insufficient to predict ...Columbia research to examine gene influence on severity of peridontal disease, therapy response
...ns of both can be quite similar, while response to standard therapeutic procedures may vary considerably. Both types of disease are characterized by swollen gums and deep periodontal pockets. Therapy usually consists of cleaning of the periodontal pockets and root surfaces, accompanied by gum surgery and adj...New treatment for fibromyalgia
...ng the Fibromyalgia Impact Questionnaire and other standard measures, for improvements in their condition. In various measures of disease--from pervasive pain to tiredness to tenderness--the female fibromyalgia patients treated with duloxetine improved significantly over those treated with a placebo. One of...Early detection hope for eye disease
...nce or progression of any disease. They modified a standard ophthalmoscope, adding a liquid crystal tuneable filter, which allowed them to take images of the retina at a series of specific wavelengths. The images are captured by a sophisticated digital camera - a cooled, low noise CCD camera. Image processin...Long-term effects of carbon monoxide poisoning are an autoimmune reaction
...with immunosuppressant agents, in conjunction with standard hyperbaric oxygen therapy," he says. "Until our study elucidated this immune response, we had no motivation to think along those lines." Penn colleagues on the paper are: Veena M. Bhopale, Donald Fisher, Jie Zhang, and Phyllis Gimotty. This study was...Chernobyl study: Risk of thyroid cancer rises with radiation dose
...en figuring out a way to maintain them without the standard resources that one takes for granted in the United States. "It's been a long haul and an enormous amount of time and work," Davis said, whose 30-plus trips to the former Soviet Union include walking the grounds of the evacuated plant and surveying th...Study reveals first genetic step necessary for prostate cancer growth
...he important difference between these mice and the standard gene knock-out strategy is that the Rb gene stays intact in all other tissues of the animal, a situation that closely resembles how genes are inactivated or lost in cancers that occur sporadically in humans. The scientists found that upon losing even...Highlights of American Chemical Society national meeting in Philadelphia, Aug. 22-26
...ge numbers of immunosuppressed individuals in whom standard antimicrobial therapy is often not effective," says Ekaterina (Kate) Dadachova, Ph.D., assistant professor of nuclear medicine at the college. "Furthermore, the specter of biological warfare has raised a new threat to humanity from infectious disease...Bright idea could doom cancer and viruses, say Purdue scientists
...offers hope that someday we may be able to replace standard chemotherapy drugs with others that are far less generally harmful to a patient's body and guarantee safe, sterile blood for transfusions." The research, which appears in the current (Aug. 23) issue of Inorganic Chemistry, was conducted by lead autho...Women who have donated eggs sought for national study
...nce monetary compensation for donating eggs is the standard in the U.S. the researchers said that it is time to analyze what role payment plays in women's motivation to donate. The on-line survey consists of 80 questions and can be completed in about 30 minutes. The research is being funded by the UW's Resea...Decreasing toxins in brains of Alzheimer's patients keep cognitive deficits at bay
...50 percent compared to Alzheimer's patients taking standard anti-Alzheimer oral medications alone. "We were very happy to see this amount of reduction," says Pratico, who adds that the research team predicted reductions only half that size. Additionally, the normal components of CSF like glucose and immunoglo...MIT research that stops pain of needle jabs gets FDA approval
...ust endure repeated needle sticks--it could become standard procedure in doctor's offices and hospitals. Another use would be before painful procedures such as angiography, balloon angioplasty, and the insertion of venous catheters. "Its wonderful to see the research we did at MIT get to the point where it ca......d in the sample. DNA and RNA chips have become a standard tool for genomics research in the last couple of years, and scientists can quite easily put a large number of different oligonucleotide pieces -- conceivably even all the known genes in an organism -- on a single chip. The Scripps Research and GNF...