Tag: "statistically" at biology news

International study findings link acne-like rash to effectiveness of new targeted cancer treatment

... Patients with a grade two/three rash had a highly statistically significant improvement in tumour response and overall survival compared to those with grade one or no rash." Professor Van Cutsem said that the trend for improved response and survival was seen across all patients irrespective of their age, sex, EGF...

Trial shows which brain cancer patients benefit from temozolomide

...tatus the two-year survival rate was only 13.8%, a statistically highly significant difference. "These results are important because temozolomide is a drug that acts directly against DNA to slow down the replication of cancer cells. So, it is bad news if the patient has non-methylated status because the DNA in the...

Preclinical safety study shows adipose-derived stem cells improve heart function after heart attack

...-up period. Additionally, the study demonstrated a statistically significant improvement in left ventricular ejecti...f dose escalation in limited infarcts, we observed statistically significant improvements in heart function. Additional swine studies are underway to better understa...

Information system to help scientists analyze mechanisms of social behavior

...vel of concepts rather than data." Technologies to statistically analyze the information sources to enable semantic indexing will be developed by ChengXiang Zhai, professor of computer science and an expert on processing natural language for information retrieval. Sandra Rodriguez-Zas, professor of animal science...

9/11 search-and-rescue dogs exhibit few effects from exposure to disaster sites

...d lifespan, the few deaths that did occur were not statistically significant," Otto said. "We can't say that these findings preclude illness later in life, but it is clear that we don't see any trends in the current physical or behavioral wellbeing of these dogs that would be cause for alarm." Initially, blood ...

New treatment for fibromyalgia

...ver their placebo-treated counterparts, it was not statistically significant. "The reasons for the sex differences in response are unclear," Dr. Arnold observes. "Because the male subgroup was small, reflecting the much higher prevalence of fibromyalgia in women, the results of the study may not be generalizable t...

New research suggests link between maternal diet and childhood leukemia risk

...the use of vitamin supplements, but did not find a statistically significant link to childhood leukemia risk. A growing number of scientists believe that genetic changes linked to cancer later in life begin in the womb. "It goes back to the old saying to expectant mothers, 'You're eating for two,'" said c...

New evidence of radiation risk in childhood leukaemia

... fallout from the Chernobyl accident. They found a statistically significant 1.6-fold increase in mutation rate in the germ-line of exposed fathers. The maternal germ-line mutation rate was not elevated. Commenting on the results of this study, Dubrova said "Experimental evidence for radiation-induced mutation in ...

Hopkins scientists use blood proteins to detect ovarian cancer

...ample size was too small for this difference to be statistically significant, the scientists conducted further studies lowering the cutoff value for CA125 to below current standards. The new test plus CA125 as well as CA125 alone detected 83 percent (19 of 23) of the cancers. In addition, the new test plus CA125...

Manatee population rising in some regions, likely stalled or declining in others

...des the information to estimate survival rate in a statistically sound manner. The estimated annual adult survival rates over the last decade were 95.6 percent in the Northwest region, 96 percent in the Upper St. Johns River region, 93.7 percent in the Atlantic region, and 90.8 percent in the Southwest region. ...

Iron can have negative side effects on people with kidney disease

...rrently in clinical trials from Pharmacosmos) are statistically different in their toxicity in this study. In highlighting the differences in toxicity among currently used iron replacement therapies, this study could ultimately impact drug selection by physicians....

Gene defects found in age-related macular degeneration

...ave contributed to AMD, but these changes were not statistically significant in terms of their comparative occurrence in AMD patients and healthy controls. However, the researchers found that seven of the 402 AMD patients each had a different change in the FBLN5 gene that was not found in the healthy control gro...

Carnegie Mellon U. imaging study reveals sex-based differences that persist as mice enter adulthood

...form a 3D reconstruction, whereas Koshibu obtained statistically relevant results in a matter of weeks with the MRM technique. Moreover, extreme manipulations of the brain needed to carry out histological investigations inevitably distort the tissue, which in turn corrupts the true brain structure, according to Ah...

Study sheds new light on genetic risk for Parkinson's disease

...on. "We found that APOE-2 conveyed a slight but statistically significant risk for Parkinson's disease, with an odds ratio of 1.2," Huang said. "This means that people with this gene have about a 20 percent higher chance of developing Parkinson's disease than people without it. Given that the overall prevalence...

Calcium supplements associated with decreased risk of large bowel polyps

...tive effect of calcium, but these results were not statistically definitive. These findings "suggest that total calcium intakes above 1200 mg are necessary, and perhaps that high dietary fiber and modest dietary fat are required to optimize this [anticancer] effect. Additional data regarding nutrient interactions ...

Researchers identify genetic markers to predict response to chemotherapy for colorectal cancer

...r side effects," Carlini said. There were no statistically significant associations between the other two UGT genes and either side effects or antitumor response. "In reality, physicians will soon be able to personalize cancer therapies based on the tumor's characteristics and the genetic profile of the per...

Drug that cuts off tumor's blood supply extends lives of colorectal cancer patients

...rouracil-based combination chemotherapy results in statistically significant and clinically meaningful improvement in survival among patients with metastatic colorectal cancer," the study states. After several disappointments with angiogenesis inhibitors, this study proves that targeting a tumor's blood supply is ...

Gene expression profiling may predict head, neck cancer recurrence

...e expression in the cell. The four subtypes showed statistically significant differences in recurrence-free survival during a 16-month period, the report said. One subtype was associated with the worst outcome; this subtype "shows an epidermal growth factor pathway activation signal, and that's potentially importa...

Other highlights in the May 19 JNCI

...oped. The tumors in mice fed the supplements had a statistically significantly decreased mutation frequency compared with tumors from mice fed no supplements. Also, transgene loss in the tumors decreased with increasing amounts of dietary alpha-tocopherol. Mutation frequency and gene loss are two types of genetic ...

Human brain works heavy statistics learning language

...non-words, showing that the human mind is wired to statistically track how often certain sounds arise in relationship to other sounds. "If you were given paper and a calculator, you'd be hard-pressed to figure out the statistics involved," says Newport. "Yet after listening for a while, certain syllables just pop ...

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