Gladstone investigator Mike McCune wins prestigious NIH Director's Pioneer Award
...nies were among the first to work on hematopoietic stem cells and the application of stem cell-based gene therapy for the treatment of HIV disease. McCune, who joined the Gladstone Ins...AAAS US Presidential Candidates' Forum
... balanced research support portfolio, put changing stem cell policy near the top, and promised to elevate ... the current ban on federal funding of research on stem cell lines created after August 2001. "Right now, more than 100 million Americans suffer from illnes......l certainly embrace the opportunities arising from stem cell research, tissue engineering research and device miniaturisation. Real opportunities exist to design nano-sized bioresponsive systems able to diagnose and then deliver drugs (so-called theranostics), and to design systems able to promote tissue ...Preclinical safety study shows adipose-derived stem cells improve heart function after heart attack
...ue-derived regenerative cells consist of (1) adult stem cells, (2) endothelial progenitor cells (blood ves...e, embryonic and fetal tissue and rarer sources of stem cells. Additionally, regenerative cells from a patient's own adipose tissue (autologous-use) present...Popular Science announces Third Annual 'Brilliant 10'
...the abstract realm of mathematics, where all facts stem from provable universal laws. Her single-mindedness helped prove the perfect-graph conjecture, a hypothesis that stumped generations of her predecessors. Kurt Cuffey , 34, University of California, Berkeley, for his work in the field of glaciolog...Joslin researchers clarify mechanisms for beta-cell formation
...t the response originates from potential beta-cell stem cells, a more primitive cell that has yet to differentiate into a beta cell. They also showed that insufficiency of a protein called PDX-1, which is critical for the development of pancreatic islets that contain beta cells, limited the growth respons...JCI table of contents September 15, 2004
...ansplanted mouse or human adult bone-marrowderived stem cells in the retinal nuclear layers of two differe...of retinal degeneration, whenever the transplanted stem cells stabilized and rescued the retinal blood vessels that would ordinarily completely degenerate, ...New fruitfly model of diabetes has future implications for pancreatic cell transplantation
...says. "Now we have a model for that." Coaxing stem cells to become pancreatic islet cells for transpl...chers trying to program undifferentiated embryonic stem cells from other tissues to grow islet cells for cell-replacement therapies," explains Rulifson. "We...Tufts University establishes $4 million dollar tissue engineering resource center
...patible tissue engineering "scaffolds" to optimize stem cell responses toward new tissue formation, and de... and morphology and the impact of these factors on stem cell differentiation toward specific tissue types, such as bone, cartilage and myocardial tissues. ...Researchers identify distinctive signature for metastatic prostate cancer
... in mice to mean that we had probably killed tumor stem cells responsible for propagating the cancers," sa...ionship of the Hedgehog pathway to normal prostate stem cells, the researchers performed experiments in mice in which they eliminated the male hormone, andr...Cell's gatekeeper for ammonia revealed in unprecedented detail
...gical disorders, from seizures to stupor and coma, stem from overexposure to ammonia. Advanced liver failure disrupts central nervous system function when ammonium ion concentrations are elevated, research shows, so the channel's high efficiency is vital. Each channel threads in and out of the cell membra...NJIT professor receives Presidential Award for breakthrough research with adult stem cells
... by President Bush for research showing that adult stem cells could help patients suffering from spinal co...rials Research that documented her breakthrough in stem cell research. The paper focused on developing scaffolds that aid stem cells. Scaffolds are biomater...How do you mend a broken heart?
...as previously shown that when a muscle is injured, stem cells can help the tissue rebuild. This team of researchers will build on her findings and use the collective expertise of the group, to develop and study human cells with an enhanced potential for cardiac regeneration. Along with Prof. Rosenthal, It...Bone marrow cells routinely help with wound healing
...orted the work. "This study shows that bone marrow stem cells, in addition to cells from the surrounding t... of purposes in recent years because it is rich in stem cells cells that can go on to become many different kinds of cells. In order to conduct this resear...Single isolated mouse skin cell can generate into variety of epidermal tissues
...titute at The Rockefeller University have isolated stem cells from the skin of a mouse, and showed, for the first time, that an individual stem cell can renew itself in the laboratory and then be used in grafts to produce skin, hair and oil gla...Genuine stem cells found in skin might treat hair loss, wounds
.... While earlier work had suggested the presence of stem cells in skin, the new study by Howard Hughes Medi... mice exhibit all of the defining features of true stem cells. The skin stem cells offer potential new methods to reverse baldness and boost wound healing i......ical implications. Learning how nature 'engineers' stem cells and molds them into specific organs will help scientists make progress in tissue engineering." The next step, says Chuong, is to look into how these areas of cell proliferation are localized physiologically, "an issue that's also of concern to ...Skin stem cells give hairless mice hair
...e findings mean that the human equivalent of these stem cells, which scientists are also trying to isolate...es and organs. Scientists are working toward using stem cells to grow mature specialized cells that could regenerate damaged or diseased skin, brain, heart ...APS awards more than $140,000 to minority students of physiology
...ow Wnt protein-activated signaling pathways direct stem cells to develop into bone rather than fat. Her lab has discovered that activation of Wnt signaling inhibits differentiation of fat cells and prevents obesity in mice. Currently, she is testing whether Wnt signaling results in fewer fat cells and mor...Columbia, Stony Brook, Guidant to develop biological pacemaker based on gene & cell therapies
...ties has demonstrated that adult human mesenchymal stem cells can be genetically engineered to express a specific gene responsible for the normal pacemaker function of heart cells. These cells are not embryonic and are obtained from adults. The researchers have shown that when cells engineered in this w...