Tag: "sticky" at biology news
Gene alterations for cystic fibrosis may also account for chronic sinus problems in some
...s in the lungs and leads to accumulation of thick, sticky
mucous that is not only difficult to clear, but also provides a breeding ground for bacteria. "Certainly many things contribute to chronic sinusitis in people who have no known family history of cystic fibrosis," says Dr. Cutting. "But we wonder...
New technique will improve delivery of drugs and gene therapy for cystic fibrosis patients
...nd airways that are partially obstructed by thick, sticky
mucus, a condition resulting from the disease," sa...ancreas, and causes a buildup of abnormally thick, sticky
mucus. This mucus causes malnutrition, stunted growth, frequent lung infection and breathing diffic...
How cells know when to stop wound-healing
... As the cells move into the wound, they lay down a sticky
bed of proteins including laminin 5. The chemical signals dissipate as the wound heals, but to fine-tune their position the cells now use alpha(3)beta(1) to crawl over the laminin 5. At some stage, however, the cells need to stop moving and settle ...
Tea fights cavities, reduces plaque
...hich is responsible for converting sugars into the sticky
matrix material that plaque uses to adhere to teeth. In addition, certain plaque bacteria, upon exposure to black tea, lost their ability to form the clumpy aggregates with other bacteria in plaque, thereby reducing the total mass of the dental plaq...
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...e, 530-752-4533, firstname.lastname@example.org . Infinitely sticky
antibodies deliver cancer treatment Using antibodies as "smart bombs" to carry doses of radiation straight to tumor cells is the aim of research by University of California, Davis, chemistry professor Claude Meares. The team has developed a new meth...
Cystic fibrosis patients show too little salt in lungs, will need long-lasting treatments
...ount of salt back, youll promote clearance of this sticky
mucus, which is the problem in cystic fibrosis lung disease, Boucher said. They also revealed that you have to have long-acting compounds to do this in a way thats going to be clinically useful. The UNC project is an important step toward understand...
Dentists abuzz over cavity-prevention potential of honeybee product
...t anti-cavity agent. The substance is propolis, a sticky
material like glue that bees make to hold their hives together. Bees create the brew by collecting secretions from trees and other plants, carrying them back to the hive, chewing up the materials, then spitting the concoction out and mixing it with b...
UC researchers have discovered novel cell adhesion mechanism that may lead to improved treatment for sickle cell disease
...esota determined that sickle cells were abnormally sticky
and proposed that this quality may contribute to b...nstein School of Medicine discovered that the more sticky
sickle cells may initiate blood vessel blockages by sticking to the vessel wall and that the more ri...
A sticky situation for ants and bees: UMass biologist looks at how these insects adhere to various surfaces
...d most other insects, Brainerd notes. "Geckos have sticky
pads on their feet, which peel off at the end of e... pair of claws that resemble a bulls horns, with a sticky
footpad called an arolium positioned between the claws. When the insects run along a surface, she ex...
Study: control of chloride channels localized, discovery may boost cystic fibrosis treatment
...ung surfaces properly. The result is excessively sticky
mucous that traps disease-causing organisms but prevents the lungs from expelling them as they normally would. Chronic infections follow, along with lung damage that eventually leads to premature death. A report on the findings appears online Tuesd...
A trillion computers in a drop of water: Scientists build a nanoscale computing machine using biological molecules
...er, resulting in a single-strand overhang called a sticky
end. Two molecules with complementary sticky
ends can temporarily stick to each other (a process known as hybridization), allowing DNA Ligase to ...
UNC, Duke researchers discover cause of mysterious pancreatitis in some people
... lungs. As a result, they produce overly thick and sticky
mucous that traps disease-causing bacteria and other organisms in their lungs and leads to chronic infections and shorter lives. Such patients can also suffer from pancreatitis -- an inflamed pancreas causing pain, poor insulin production and frequen...
Gene therapy corrects sickle cell disease in mice, Science authors report
...emaglobin, in which the beta globin chains develop sticky
patches when they lose their oxygen. These sticky
patches cause the molecules to adhere to one another and link themselves into long fibers that stret...
Research uncovers new treatment target for cystic fibrosis patients lung infection
...e airways or are localized on cell surfaces in the sticky
mucous overlying those cells, he said. Using electron microscopy and several sensitive techniques, we found, not surprisingly, that the infections were in the mucous. Researchers then reasoned that the most common bacterium infecting CF patients, Ps...
Stanford researchers home in on Huntington's disease treatment
...ew that a compound called cystamine could keep the sticky
protein, transglutaminase, under wraps. So, his former graduate student, Marcela Karpuj, PhD, now a postdoctoral fellow at University of California San Francisco, began treating their sick mice with cystamine injections. The treated mice show...
Undergraduate unraveling genetic mysteries in fruit flies
... underside of the bottles stopper is coated with a sticky
substance that collects the fertilized eggs. Comeaux learned to apply an antibody stain to these fly embryos to identify the cells that are forming the insects salivary gland. Under a high-powered microscope she was able to see how a genetic mutation...
Novel gene therapy approach in 1st human trials
...airways. In turn, the airways accumulate thick and sticky
mucus. Bacteria proliferate in the mucus and cause chronic infections that permanently damage lungs. Under the direction of Dr. Konstan, the research team delivered the healthy gene into CF patient Robert Calhoun in a saline solution dripped slowly ...
New findings could lead to innovative treatment technologies for patients with sickle cell
...o abnormally sticky. The combination of rigid and sticky
red blood cells causes generalized bone pain, as well strokes, and failure of the lungs, liver, and kidneys. The only approved treatments for this disorder are pain relief, adequate hydration, oxygenation, bone marrow stimulation, and blood transfus...
CF Foundation seizes proteomics for drug discovery
...ters. The result: lining organs abnormally thick, sticky
CF mucus that causes major problems in the airways and digestive tract. Researchers know that the CFTR protein interacts with a large number of other proteins in the cell but are just beginning to understand what those proteins might be and how thos...
Protein complex found to regulate first step in human blood clotting
...rive at the wound, which change shape, sending out sticky
arms into the blood flow to recruit other platelets that attach in an organized matrix to stop the bleeding and maintain the vessel. Stroke, which results from abnormal clotting, is treated with blood thinning compounds to block platelets from formin...
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