SFU Molecular Biologist Pursues 'Promising' New Way To Fight Disease
...ed a promising new way to create a vaccinethat can stimulate the body to produce just the two or three antibodies that aremost effective at preventing a virus like HIV-1, the AIDS virus, from attackingthe body. A traditional vaccine against AIDS would use a 'shotgun' approach,stimulating the body to p...Salmonella Vaccine Now Available For Poultry
...is vaccine is designed to live only long enough to stimulate an immuneresponse in chickens and then is eliminated by the chickens' immune system toassure food safety at processing. It is very specific for Salmonella control,very low cost at less than one cent per bird and is easily applied usingtraditional tec...Allelix drug increases bone density and content in women with osteoporosis
...cts on bone generating cells called osteoblasts to stimulate new boneformation. Additional preclinical studies have demonstrated this new bone is ofnormal architecture and strength. Postmenopausal osteoporosis affects one in four women older than 50 in theUnited States -- some 8 million - according to the Nat...Genetically Engineered Mice Exhibit Anxiety, Offering Insight Into Role Of Serotonin In Brain
...their nest. Because antidepressants such as Prozac stimulate 5-HT-1A receptors, amongothers, the researchers also sought to compare the behavior of the mutant micewith that of mice treated with antidepressant drugs. While they stress thatfurther studies are needed to confirm their observation, their initial fi......gh levels ofIGF-I production in aging muscle might stimulate more effective repair andregeneration by the satellite cells, which proved to be the case. If this work is to be extended into humans, a number of ethicalconsiderations will need to be addressed, according to senior author Sweeney. "T...Molecular Doorway Holds Key To Gene Therapy
...his colleagues are also gearing up to find ways to stimulate cells to produce more integrins on their surfaces, thus enhancing the chances of successful gene delivery. Summerford notes that white blood cells calledmonocytes can be removed from an individual and genetically induced to "express"a greater number ...Scientists, Using Flies, Trace Genetic Links To Cancer
...chers in hislab have started mapping pathways that stimulate cancerous growth, beginning ingenetic material and culminating in deadly tumors. Perhaps even more noteworthy, he says, is that one of the genes in the mostrecent fly experiments corresponds to a human gene that has been implicated inthe spread of ca...Wolf Prize In Medicine Awarded To Kandel, Columbia's Pioneer Of Memory Research
...alled CREB. CREB switches on dozens of genes that stimulate thegrowth of synapses, which lead to the formation of persistent, long-termmemories. In 1990, Professor Kandel's team found that by blocking CREB, allthese events were halted, indicating that CREB was a key to the genetic basis oflong-term memory. ...Skeletal Muscle Yields Precursors Of Bone Cells That Form Bone When Transplanted Into Animals
...into the cells so that they couldproduce bmp-2 and stimulate their own transformation into bone," noted Dr.Huard. "We also put in a marker gene that would allow us to track the movementof the cells within an animal." The research team injected the genetically altered muscle-derived cells intomuscles of SCID m...Old Bone Collection Reveals Basis For Some Dizziness
...es in their balancecanals and using loud noises to stimulate eye movements, he provided the firstevidence that balance disturbances are linked to the direction of eye and headmovements. Roughly half of the 15 SCDS patients Minor has diagnosed and treated canpoint to a specific event that brought on the...UCSD And NIH Researchers Isolate Candidates For Genetic Basis Of Human Taste
...gnize highcaloric food, while bitter receptors can stimulate an aversion to noxioussubstances.The mechanism of taste in mammals begins with the taste buds on the tongue.Sweet receptors are mostly found on the tip of the tongue; sour receptors on thesides; salty on the tip and frontal sides; and bitter on the b...Researchers Discover Genetic Mutation For Rare Form Of Dwarfism
...ptor makes it impossible for chemical signals that stimulate growth of bonesto be "heard"; therefore, bone growth is markedly impaired. The study suggests that defects in the receptor may be a more commoncause of growth hormone deficiency than previously suspected, Levine says. "This family se...Heat-Shock Vaccine Stops Bacteria Dead
...ttach vaccine molecules to "carrier" proteins that stimulate T cells and enlist themin the antibody production ...ral immunity to these proteins, which are known to stimulate T-helper cells. "Heat-shock proteins are perfect enhancers of the T-helper cell response,butbecause ...Coffee Without Addiction, Possible New Treatment For Osteoporosis, Wrinkle-Free Cotton, And More
...sful, could be the first osteoporosis treatment to stimulate newbone growth rather than simply retard bone loss. The treatment is showingpositive results in animal studies and can be put in pill form. A New Wrinkle in No-Wrinkle Cotton: A new cost-effective and environmentallysound finish for cotton fabri...Alcoholics' Children: Living With A Stacked Biochemical Deck
...ward system,making it easier for drugs of abuse to stimulate it. Cortisol is probablyincreased in those prone to alcoholism. "So someone who has a small drink wouldget a bigger reward from the overdeveloped system; the reward gets amplified,"says Wand. "These children of alcoholics may have a double-......ue surrounding nerves,including factors that could stimulate new nerve growth. The study, carried out by scientists from the National Institute of Dental andCraniofacial Research (NIDCR) and the University of Pennsylvania, was reportedin the May 1 issue of Human Gene Therapy. "We are totally pumped up that th......ect." Bernstein said. If the work leads to away to stimulate heart muscle repair, it also could help the 900,00...nal regulation of thenormal cell division cycle to stimulate myocardial cells to proliferate, thereare experimental methods currently being tested in other labs ......tially be used - as interleukin-2 is now used - to stimulate dormantHIV-1 virus in tissues of patients who have undetectable viral load, to 'flushout' the virus." Tuesday, May 4, 1 p.m., "Bosma Arhinia Microphthalmia Syndrome," John M. Graham,Jr., M.D., Sc.D., director of Clinical Genetics and Dysmorphology at......hesecrippled bacteria work as a vaccine since they stimulate immune defenses todefend against subsequent infections." Vaccines and antibiotics developed out of this discovery are expected toprovide a major boon to human health worldwide, particularly in countries wheremany people die from bacterial inf......, more aggressive therapy combined with therapy to stimulate thepatient's own immune system may prove to be effective therapy." The cancer vaccine used in the study, THERATOPEO vaccine, is currently beingevaluated in a pivotal Phase III clinical trial which will involve 900 evaluablepatients with metastatic br...