Tag: "stimulates" at biology news

Technique brings immune-based therapies closer to reality

... coating them with HLA-Ig and another protein that stimulates cell growth and exposing the beads to antigens from either melanoma or cytomegalovirus. "Using the aAPCs, we were able to make a tremendous amount of CTLs while maintaining their specificity," says Schneck. "Losing specificity as CTL numbers rise ...

Gene therapy may be a cure for post-radical prostatectomy erectile dysfunction

...rnous nerve. The cavernous nerve is the nerve that stimulates erection; cryo-injury has similar effects on the nerve as radical prostatectomy. After injection, they found that the viral vectors transported the neurotrophic factors to the nerve. On electrical nerve stimulation, nerve-injured rats that expressed ...

What goes wrong in older eggs?

... "We normally feed our fruit flies yeast, and that stimulates egg development," said Bickel. "However, in these experiments, we gave them yeast for a day, to allow their eggs to mature, but then we took them off the yeast and put them on sugar for four days. Although they had a food source that kept them health...

Immune cells may help deliver cancer vaccines for children

...onse could form the basis of a cancer vaccine that stimulates the body's existing immune system," said Christina M. Coughlin, M.D., Ph.D., who presented the research today at the annual conference of the Pediatric Academic Societies in Seattle. Unlike routine childhood vaccinations such as those given to preven...

A new discovery by scientists at the MNI may provide insights into Multiple Sclerosis

... very important for MS. If we can understand what stimulates them to function, then perhaps we can develop new targets for therapy," explained Dr. Jack Antel, a neurologist at the Montreal Neurological Institute specializing in the research and treatment of MS....

Chemical in broccoli blocks growth of prostate cancer cells

... primary androgen involved in prostate cancer. DHT stimulates the expression of prostate specific antigen (PSA), which acts as a growth factor for prostate cancer. When androgen-dependent cells were treated with DIM, the researchers found a drop in the level of PSA. "There are lots of things that can stop grow...

JCI table of contents, May 15, 2003

...iers and estrogen TITLE: HDL-associated estradiol stimulates endothelial NO synthase and vasodilation in an SR-BIdependent manner AUTHOR CONTACT: Eric Smart University of Kentucky, Lexington, Kentucky, USA. Phone: 859-323-6412 Fax: 859-323-1070 E-mail: ejsmart@uky.edu View the PDF of this article at: https:...

Green tea boosts antimicrobial properties of toothpaste

...es Tea Helps Fight Infection, April 2003] that tea stimulates the immune system to fight disease," says Milton Schiffenbauer, Ph.D., a microbiologist and professor in the Department of Biology at Pace University's Dyson College of Arts & Sciences and primary author of the research. "Our research shows tea extra...

Gene therapy grows new auditory hair cells in mammals

...nt of the inner ear. When cochlear fluid moves, it stimulates movement in thousands of tiny projections on hair cells lining the inside of the cochlea. Moving hair cells initiate electrical signals, which are picked up by auditory nerve fibers and carried to an area of the brain called the auditory cortex. If h...

Researchers find new way to trigger self-destruction of certain cancer cells

... the action of a protein called mTOR. This protein stimulates a biochemical pathway that leads to increased production of proteins essential for cell proliferation. Blocking mTOR with rapamycin leaves the cell unable to make these critical proteins. Blocking the activity of mTOR with rapamycin triggers a bioche...

JCI table of contents, July 1 2003

... theory presents a double-edged sword as VEGF also stimulates abnormal vessel growth that can ultimately result in leaky vessels. In order to wisely skirt this catastrophic event, Lois E. H. Smith and colleagues utilized placental growth factor-1 (PlGF-1), which exclusively activates the VEGF receptor-1 (VEGFR-...

Protecting vessel loss in the eyes of premature infants

... theory presents a double-edged sword as VEGF also stimulates abnormal vessel growth that can ultimately result in leaky vessels. In order to wisely skirt this catastrophic event, Lois E. H. Smith and colleagues utilized placental growth factor-1 (PlGF-1), which exclusively activates the VEGF receptor-1 (VEGFR-...

U.Va. researchers discover mechanism for the regulation of low-voltage-activated calcium channels

...terior. Because elevation of calcium within cells stimulates cellular activity, regulation of calcium entry is an important way by which the function of cells can be controlled. The research uncovered that only one member of a large family of G-protein subunits binds directly to the calcium channel protein to ...

Researchers identify molecular signaling system that is crucial for plant fertility

... is present at the surface of the pistil, where it stimulates pollen tube growth. Higher concentrations are found closer to the eggs, leading the tubes toward the target. The study grew out of the team's chance finding of abnormal pollen tubes on plants that were later found to lack POP2. "We saw the pollen ...

Protein holds promise as new diabetes drug target

...und improves insulin secretion by the pancreas and stimulates glucose usage by the liver, both of which are abnormal in diabetes."Magnuson cautions that it's too early to tell what the real value of a glucokinase-activating drug might be. Clinical trials are still in the planning stage. "It has dramatic effec...

New compound class found to trigger changes in cell garbage can

...ds because of its multiple roles as an agent that stimulates vessel growth, inhibits inflammatory responses and kills bacteria. Coauthors include Mark Post, visiting associate professor of medicine at DMS, as well as M. Maria Gaczynska and Pawel A. Osmulski, of the University of Texas Health Science Center a...

Birth control for brain neurons

...ences, shows that blocking nitric oxide production stimulates neural stem cell proliferation and hence dramatically increases the number of neurons that are generated in the brains of adult rats. Importantly, the new neurons that arise as a consequence of blocking nitric oxide production display properties of n...

Data privacy, emergency response, weather prediction to benefit from information technology advances

...his critical area." The ITR program encourages and stimulates innovative, high-risk and high-return multidisciplinary research that extends the frontiers of information technology, improves our understanding of its impacts on society, helps prepare Americans for the Information Age, and reduces the vulnerabilit...

Study of bees by UC San Diego biologist provides insight into evolution of bee communication

...he bees to attack could later change into one that stimulates bees to eat. "Thus mandibular gland odors could enable foragers to draw in reinforcements precisely where they are most needed to take over a rich food source," Nieh surmises....

Cellular fat sensor slows heart disease

...lerosis. "Immune cells promote inflammation, which stimulates the transport and absorption of fat that triggers the early stages of heart disease," Evans said. "Our study uncovered the molecular switch that regulates this process and reveals how the inflammatory response, designed to fend off invading agents, c...

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