Mouse with iron disorder offers clues to Parkinson's, similar diseases
..."knockout technology," the researchers developed a strain of mice lacking the IRP 2 gene. These mice developed normally at first, then progressively had difficulty walking and moving. Examination of their brains showed that tiny clumps of iron accumulate in the cerebellum, the brain structure controlling ...New grain variety opens up possibilities for Australian farmers
...ls in overseas markets." Early trials with the new strain have been very promising. "Feeding trials at the Pig and Poultry Production Institute on Adelaide Universitys Roseworthy campus have shown that low toxin (<0.45%) lines of common vetch, can be tolerated by three week old chicks," said Dr Tate. "H...Oncogene spawns further mutation in breast cancer study
...y, not just later in life. Instead, they created a strain of mice that would express human MYC on demand. By mating transgenic MYC mice with a strain of mice that would turn genes on in the presence of an antibiotic, the researchers were able to crea...Tips from the journals of the American Society for Microbiology: February 2001
...ecific (one that does not cause disease in humans) strain of the bacterium Campylobacter jejuni just days after hatching results in the animals becoming colonized with that strain, crowding out any strains potentially harmful to humans. "Our results suggest that it is possible to use combinations of C. jeju...Genomic analysis of pathogenic and benign gastritis bacteria
... of this single gene in a B128 background yields a strain whose effects in culture and in vivo mimic those of G1.1....Tips from the Journals of the American Society for Microbiology: March 2001
...S Pigs experimentally infected with a human strain of the hepatitis E virus (HEV) develop the disease...ople. Several years ago, scientists discovered a strain of HEV in pigs that was genetically similar to human HEV, suggesting that pigs could be reservoirs f...New egg-free flu vaccine called promising for those with egg allergy
...each year based on the likelihood that a new viral strain will occur. Influenza is a respiratory infection that contributes to 20,000 deaths in the United States each year. At greatest risk are infants, the elderly and people with certain chronic conditions such as diabetes. Flu season typicall...Hormone the trigger for fat metabolism; scientists closer to tests in humans
...gy resulting in weight loss. "We treated a new strain of mice with the hormone MSH and our findings confirm its role in the control of fat levels in the body. The effect of this hormone on fat cells validates our theory," said Miles B. Brennan, Ph.D., a scientist at ERI. "Despite the perception in both ...Researchers light the path of brain's feeding circuit in mice
... cells. In this paper, the authors created a viral strain that would be activated only in specific cell types but remain inactive in others. This new strain is activated when it infects a cell that expresses another gene known as the Cre recombinase. The r...Mice nibbling at the secrets of NF1
... Ras activity. Previous attempts to create a mouse strain that lacks the NF1 gene have been unsuccessful bec...ue, Dr. Parada and his team were able to produce a strain of mice in which the NF1 ablation is restricted to mature neuronal cells only. This conditional NF1......olleagues found the cancer antigen by looking in a strain of mice prone to prostate cancer. They treated the mice with a therapy they discovered for unleashing the immune system against prostate tumors - a therapy that is now in Phase I human trials at two hospitals in California - and looked for those mice...Scientists sequence genome of strep throat, scarlet fever bacterium
...head of the genome sequencing team. The particular strain of S. pyogenes that Dr. Ferretti and his colleagues examined, designated SF370, was isolated from the infected wound of a patient and can cause invasive diseases such as streptococcal toxic shock syndrome or necrotizing fasciitis. Preliminary analysi...USGS issues wildlife health alert for foot-and-mouth disease
...hite-tailed deer are susceptible to the same virus strain now affecting domestic animals overseas. The same studies also showed that infected deer could shed virus up to 4 weeks after infection and could pass the infection to other deer and cattle. Likewise, infected cattle are able to pass the virus to dee...Immune system helps prevent tumors after all
...plore further. In this current paper, they used a strain of mice that completely lacked functional lymphocytes. This was accomplished by inactivating a lymphocyte-specific gene called RAG2. When these mice were injected with the chemical carcinogen MCA, 58 percent of them developed tumors. In previous stud...Scientists: nutritional deficiency can boost influenza virus damage
.... They later exposed both groups of mice to a mild strain of human influenza virus known as Influenza A Bangkok. Rodents consuming too little selenium developed significantly more harmful lung inflammation, which also lasted considerably longer, than animals that developed the flu but whose diets were norma...Disadvantaged children perceive more hostility, damaging their hearts
... external threats, often translating into an added strain on their cardiovascular systems, according to the study. The study by Edith Chen, Ph.D., of Washington University in St. Louis and Karen A. Matthews, Ph.D. of the University of Pittsburgh fills in some new pieces of the puzzle as to why people who gr...New molecular key to disposal of dying cells
...ed to their development of a Mer knockout mouse, a strain of mice defective in Mer function, which would provide insights to the function of Mer. UNC researchers have been studying the role of Mer in cancer development because Mer, like Axl, is found on cancer cells. After further study, it appears that M...Finding a model, finding a cure
...ana-Farber Cancer Institute have generated a mouse strain with an inherited mutation in Brca1. The breast an...d, BRCA1 protein. The scientists generated a mouse strain with a truncating Brca1 mutation that similarly eliminates the C-terminal portion of the BRCA1 prote...Technology patented to create Pierces disease-resistant grapevines
...y in the water vessels of a variety of plants. The strain that lives in grapevines clogs the vessels, causing the plant to dry up and die. First detected in Southern California in 1884, the disease had been a minor problem in West Coast viticulture for decades. In the mid-1990s, however, it became preval......e anticipate that the ability to get DNA into this strain of Streptomyces will lead to the production of nov...they transfer DNA into. The researchers used a strain called Streptomyces coelicolor, which is the most genetically well-characterized actinomycete, an ex...