MIT Biologists Identify Aging Mechanism
...they wereoverexpressed, the life span of the yeast strain was extended. The research also showed that the gene products encoded by SIR2, SIR3and SIR4 promote cell longevity by moving from one cell structure to another(from the telomeres to the nucleolus). This action and the fragmentation of thenucl...DNA Enzyme Works In Crystal Form; Yields New Insights Into Gene Copying
... Stratagene had isolatedfrom a recently identified strain of a bacterium called Bacillusstearothermophilus that is found in hot springs in Idaho. The biochemists foundthis new polymerase seemed to produce superior crystals with DNA incorporated.But they were quite unprepared for the discovery that the enzym...DT104 Advice:How To Slow Salmonella Spread
...104: "Fingerprint" identification of a particular strain ofsalmonella, such as DT104, is multi-step process. Among the techniques at thediagnosticians' disposal are serogrouping and serotyping, phage typing,antibiograms (antibiotic resistance profiles), plasmid profile and plasmidcompatibility grouping, P...Good Ergonomics Is Good Economics
... implementing the training, the number of reported strain injuries was 12 for the six months prior to training and 10, 16, and 25, respectively, for the next three six-month periods. In short, things got worse rather than better (Bill Brough, personal communication and supporting documentation). Coupled w...Corn Rootworm Changing Behavior, Posing New Threat To Crops
...t crop rotation itself has selected for a rootworm strain that circumventscrop rotation. By laying their eggs in soybean fields, the female rootwormbeetles ensure the survival of their larvae in the subsequent year becausethe field will be planted with corn. "Intense selection pressures have produced root...Duke Researchers Develop First Treatment For Rare Muscle Disease
...gical Science, Kobuchizawa, Japan, who developed a strain ofJapanese quail also missing GAA. These birds can't fly and when turned on theirbacks can't right themselves. The team of researchers used three test groups of birds. Two birds wereinjected with a high dose of purified human GAA, two with a...U.S. Scientists Honored For Lifetime Contributions In Hepatitis Research
... vaccine in China; discovery of a new strain of hepatitis D virus in the jungles of Brazil; and studies on the epidemiology of hepatitis E virus in Pakistan. Anthony S. Fauci, M.D., director of NIAID, said of Drs. Pu...Biotech Approach To Feral Cat Problem Devised
... use of genetic engineering technology to modify a strain of the bacterium, Salmonella, which could then be ... in people and animals, Boyle says, the attenuated strain cannot cause disease. The Salmonella bacterium is especially useful as a vehicle for delivering an ...Long-Standing Puzzle Of Immune System Is Solved By UCSF Researchers
...es, we would likely have succumbed to an Andromeda strain longago," Wabl says, referring to a popular science fiction thriller starring anewly arising microscopic scourge that threatens human life on Earth. The cellular agent identified by the UCSF researchers as the oneused by B cells of the immun...Biologists Map First Gene For Age-Related Hearing Loss In Mice
.... The researchers worked with the C57BL/6J inbred strain ofmice, the most commonly studied strain in age-related hearingloss research. Its abbreviated name is the B6 mouse. Larry Erway, professor of...Uterine Environment Boosts Learning Ability In Mouse Offspring
...y involved genetically identical mouseembryos of a strain known as BXSB/MpMob-+Yaa. The BXSB strain, developed at TheJackson Laboratory, is a popular model for the study of lupus-like autoimmunediseases and such conditions in mice as neocortical ectopias similar to thosefound in the brains of human dyslexic...Virulent Fungus Devastating Potato Crops
...ook an estimated 1 million lives, a newer virulent strain of the fungus is causing widespread crop devastati...rofessor of plant pathology. Fry believes the new strain of the fungus is a greater threat to potato and tomato crops in the U.S. and Canada than were previo...Change In HIV May Precipitate AIDS
...s. Later in the course of the disease,a different strain of the virus often predominates, and that strain is called"T-tropic," because it attacks T lymphocytes almost exclusively. Researchers specul...Researchers Discover Ways The Ulcer/Cancer Bug Can Trigger Disease
...unfortunate enough to be infected with a bacterial strain that can bind to thecells lining your stomach and, second, the bacterium contains molecules on itssurface that resemble some of those on your stomach cells -- the destiny of theinfection may be skewed toward autoantibody production, loss of acid-pro...Obscure Enzyme May Play Major Role In Heart Disease
... that relationship. In experiments with a strain of mice that are vulnerable toatherosclerosis, an inverse relationship between cholesterol oxidation andparaoxonase activity was shown. In addition, an increase in the size of theatherosclerotic lesions in the blood vessels of these mice was found to...Researchers Discover How Ulcer Bug Becomes Antibiotic-Resistant
...ations in the rdxA gene that had made the parental strain metronidazole-sensitive. "This indicates that mutation is the easiest way for resistance to arise in H.pylori," Berg says. "Our guess is that it occurs because the bacterium converts metronidazole to hydroxylamine, a powerful mutagen, and use of metr...Researchers Discover Existing Drugs May Prevent Enlarged Hearts
...d two strains of mice totest their hypotheses. One strain continually expressed activatedcalcineurin in hear...ne could signal thehypertrophic response, a second strain of transgenic mice was designedto express activated NFAT3 in heart muscle cells. These transgenic mi...Duke Researchers Genetically Engineer Mice To Block Heart Enlargement
... blood pressure and cloggedcoronary arteries put a strain on the heart. As it tries to compensate, the bodyp...itors, toblock the various hormones that produce a strain on the heart. If these drugsfail and the disease progresses, patients can receive a heart transplant......ph. Itwas the first time that the possibility of a strain of bacteria resistant to anyantibiotic had appeared since penicillin became widely used in the 1940s. In order for disease to result from bacterial infection, the expressionof a series of genes must occur, allowing the prospective pathogen to...Virginia Tech Scientists To Evaluate Risks Associated With Release of Recombinant Organisms
...zana."We will be evaluating the potential for this strain to be transmitted tocontact pigs in small and large herds as well as transfer of its foreign DNA toother microorganisms." While recombinant organisms are being developed in laboratories aroundthe world, Inzana explains, some questions exist ...