New research illustrates role of CETP in atherosclerosis
...model that carries the human gene forCETP in a rat strain that develops high blood pressure. As they aged, such rats developed severelyhigh cholesterol and triglyceride levels, atherosclerotic lesions, myocardial infarctions (heartattacks), and had decreased survival, thus closely mimicking human atheroscle...West Nile Virus may be new deadly strain, USGS tells Congress
...ive birds or it may represent a new, more virulent strain of the virus." Resident and migratory birds may play an important role in natural transmission of the virus and in maintaining the virus in the United States, McLean testified. "Migratory birds could also spread the virus to other states outside ...Human stem cell research leads Science's top ten list of the best scientific advances in 1999
...onstrated when scientists genetically engineered a strain of mice that produced an abundance of one such molecule and were unusually successful at learning mazes. A Plethora of New Planets: Reports of new planets in neighboring solar systems poured in throughout 1999, increasing the tally of known extra-s......ous research has shown that some men have the same strain of HIV in their blood and semen, while others exhibit differing strains. "Interestingly, we now see that those with the same strains in blood and semen are continuous shedders, while those with distinct virus populations are intermittent shedders," ...Scientists link gene to uterine dysfunction
...e females, reduced uterus weight. However, in one strain the females suffered from near complete reproductive dysfunction, with complications during pregnancy that were fatal to the pups or mother. The other two strains appeared reproductively normal at first, but deteriorated with maturity so that the mi...Obesity gene controls bone density via brain pathway
...rmal weight, but also had dense bones. Yet another strain of mouse that was unable to produce either fat or leptin, nonetheless had very dense bones. "It may be possible to manipulate the leptin pathway in a way that increases bone mass, but avoids the adverse effects on weight and fertility," said Dr. Kar...Scientists develop most efficient mouse cloning strategy to date, create transgenic clone
...ansfer, 7 of the 34 embryos21percentfrom the first strain developed to term and grew into healthy adults. B... 8 of 76 embryos made from the second, more inbred strain developed to term. All 8 died within 24 hours after birth, demonstrating that genetic make up of do...Common anti-inflammatory drug rescues low-growth fetuses in mouse study
...ennsylvania Medical Center report development of a strain of mice in whom pregnancy leads to a condition tha...e affected fetuses. By genetically engineering a strain of mice to overexpress the receptor for thromboxane, the researchers were able to exaggerate the res...... Infection and Immunity. Hillman constructed a new strain of the decay-causing bacterium Streptococcus mutan...gene responsible for lactic acid production from a strain of Streptococcus mutans," said Hillman, a professor of oral biology at UF's College of Dentistry. "...Bacterial strain may help clean up harmful industrial waste
...g to unravel. Under his microscope is a bacterial strain called T1 capable of breaking down one of the most...University Medical Center discovered the bacterial strain T1 about 10 years ago, digging through the mud at contaminated sites in search of an organism in the...... has been shown to be effective against a specific strain of the disease. In 1997, Chiron and TIGR established a collaboration to sequence the genome of Neisseria meningitidis in order to develop a vaccine against meningococcal B disease. Under the terms of the agreement, Chiron has the exclusive right to ...Repetitive DNA in the genome of Neisseria meningitidis
...re described in March, 2000, that of a serogroup B strain (Science 287: 1809-1815) and that of a serogroup A strain (Nature 404: 502-506). Only 91% of the coding sequences of each genome is present in the other strai...Genetic mutations associated with epilepsy
...initially studied mutations in a related gene in a strain of laboratory mice with seizure disorders. Using recent data from GenBank---an Internet database where scientists in the publicly funded Human Genome Project post their gene sequencing data---Escayg located the genetic coding of the human SCN1A gene...Researchers identify unique circadian rhythm photoreceptor
...y Hall at Brandeis University, however, there is a strain of mutant flies that maintains a steady clock when barraged with intense light. The flies carry a crippled light-reactive pigment called a cryptochrome. Experiments by Rosbash and his colleagues now indicate that the fly cryptochrome dCRY is perhap...Scientists move in on genes conferring susceptibility, resistance to cancer
... laboratory, so that all of the animals in any one strain are genetically identical; the second species, known as Mus spretus, is, by nature, highly resistant to tumor development in several organs, such as the lung, skin, liver and colon. The investigators made hybrids between these two types of mice to ...Oral exposure to anti-oxidant glutathione could help prevent flu infections
...n infected two groups of mice with a mouse-adapted strain of a human influenza virus. The mice that had been given drinking water containing glutathione had a significant decrease in viral production compared to animals whose water did not contain glutathione. "It appears that by going directly to the ...Northwestern team identifies first enzyme in mammalian circadian clock
...on a known circadian gene mutation called tau in a strain of Syrian hamsters. The researchers bred a normal strain of hamsters with the tau hamsters, and then tested the offspring's circadian behavior. The animals b...Study contradicts assumption that ulcer bug has always plagued humans
...e. The rare type IV motif showed up in one English strain and two strains from West Virginia, and the type V motif was found in a few of the Indian strains. "So we can type H. pylori strains from different societies by differences in their DNA," Berg says. "One of the most striking differences was betw...Chemical from venom of Chilean tarantula could aid treatment of heart attack, other major diseases
...n the final fraction, Suchyna was able to induce a strain of bacteria to express the pure peptide. The recombinant peptide blocked the channels as well as the peptide that came directly from the spider, their research showed. Sachs said this result opens the door to studies that require large amounts of ......s implanted engineered human gingival cells into a strain of mouse that has no immune system and therefore does not reject foreign tissue. To their surprise, the new bone that formed in the mice was composed of both mouse and human tissue. "This suggests that the gingival cells were not just delivering BM...