From a single DNA strand, a tiny motor
...had built a tweezer-like motor that used synthetic strands of DNA for its structure. The motor had four DNA pieces: two for the tweezers V-shape, one that prompted the tweezers to close, and another that prompted the V-shape to open, according to news articles. At least one other group later announced anothe...Parasite or partner? Study suggests new role for junk DNA
...r L1, elements can jump to chromosomes with broken strands of DNA, slip into the break and repair the damage. Transposable L1 elements make up 17 percent of our DNA, but very little is known about them, says John V. Moran, Ph.D., an assistant professor of human genetics and internal medicine in the U-M Medi...New process makes genome sequencing more efficient
...alue of Cot analysis. The method splits the double strands of DNA into single strands, or denatures them, and then allows them under controlled conditions to renature, or recouple into double strands. Cot analysis breaks down a complex genome into three populations: highly repetitive (HR), moderately repetit...Scientists produce long, hair-like nanotubes
...fied method for making long, continuous, hair-like strands of carbon nanotubes that are as much as eight inch...hnique to grow nanotubes, has a high yield of long strands when a sulfur-containing compound and hydrogen are added to the process. Researchers have previously...Disorder forces DNA molecules out of tight spaces
...y spaces could lead to a method for separating DNA strands by length. It also could throw light on the way m...es. Now they are the first to demonstrate how DNA strands are ejected from confined spaces. In water, strands of DNA or other long-chain molecules tend to coi...Gene mutation influences filtering of blood by kidneys
... the kidneys. Mature podocytes have long branching strands that entwine capillaries within the kidneys. Normally, these strands work with strands from neighboring cells to form a molecular meshwork, or slit diaphragms, that prob...Researchers find synthetic molecules that may literally be the key to 'locking away' unwanted DNA
...]4+, is an iron triple helicate with three organic strands wrapped around two iron centres to give the cylinder shape (a metallo-supramolecular cylinder) which neatly fits within a DNA helix. Indeed the Supramolecular Cylinder is about the same size as the parts of a protein that recognise and bind with par...New tool speeds study of mammalian protein function
...f double-stranded RNA. These then bind to matching strands of messenger RNA, neutralizing it and causing it to be degraded, thus interfering with protein synthesis. This effect of "knocking down" a gene's expression has broad practical applications--for example, to screen for protein function by seeing what...Novel gene therapy approach in 1st human trials
... They developed a way to compact or tightly bind strands of DNA so that it is tiny enough to pass into the cell and then into the nucleus. Once inside a cell, researchers hope that the DNA will produce the normal version of the protein needed by cystic fibrosis patients. Thirteen years ago, scientists dis...Unexpected links found between many RNA viruses
...en a year in developing countries -- separates its strands and copies one to replicate itself. Ahlquist and his colleagues discovered that, although the viruses seem to take distinct routes to replication, all three types use related pathways and structures to replicate their genes. By linking three of the s...Physics tip sheet #3 March 6, 2002
...t these types of materials could be built with DNA strands or could be built with nanotechnology. Thermal diodes could reroute excess heat in a microchip or thermal transistors might run a lab-on-a-chip where temperature controls biochemical reactions. Physical Review Focus: http://focus.aps.org/v9/st11.htm...New technology may benefit health care, bioterror defense
...this," she says. Within each living cell are long strands of DNA, the genetic code containing all the information to create and control every cell in an organism. DNA resembles a long spiraling ladder, and the rungs of the ladder are made up of chemical units called bases. Clusters of bases make up our gene...Optical tweezers show how DNA uncoils
...Y. -- By using optical tweezers to pull individual strands of chromatin -- the DNA-protein complex that chromosomes are made of -- researchers have seen for the first time how information in fundamental genetic packaging units, called nucleosomes, might become accessible to molecules that "read" it. The rep...Electrodes and nanoprobes signal new DNA detection method
...aced on a glass slide, each test made up of single strands of synthesized DNA, or oligonucleotides, with a se...tween the match of two perfectly complementary DNA strands and the near-perfect match where just one base pair was wrong. The conventional fluorescence method ...February media highlights - GSA Bulletin
...part of it is active today. We have mapped various strands of the Seattle fault zone and its spatial relation to the Seattle basin, using the aeromagnetic data to interpolate fault locations between widely spaced seismic-reflection profiles and sparse bedrock exposures indicated by geologic mapping. Thus map...Tiny molecular change inactivates tumor suppressor gene in neurofibromatosis
.... In human cells, DNA and RNA molecules consist of strands of building blocks known as nucleotides that are described as a sequence of four letters. For RNA, the letters are ACGU. Davidson and colleagues found that when the NF gene is copied into mRNA, a C at a specific spot is replaced by a U. That changes ...NYU scientists advance toward nanorobots
...of these structures use base pairing, which allows strands of DNA to be programmed to self-assemble in well-d...cture. This is done by inserting DNA set and fuel strands into individual molecule pairs. Scientists used paranemic crossover (PX) (see figure 1) molecule p...Method quickly surveys yeast genome by gene function, not sequence
... "We're interested in how cells break strands of DNA and put them back together again, so we use...wo strands, DNA may be irreparably damaged if both strands break in the same area. By adding what would seem to be "broken" DNA to the yeast, the scientists t...Required activation 'cascade' identified for p53 tumor-suppressor protein
...s still developing. In this emerging scheme, long strands of DNA are seen to coil themselves around histones to create sub-chromosomal structures called nucleosomes. Genes along the tightly wrapped DNA cannot be physically accessed by the cellular machinery of transcription, and so their expression is repre...... proof that Sleep`s theory is correct. But several strands of evidence are highly suggestive. The first is that two of the three major branches of life that exist on Earth today - Archaea, Bacteria and Eukarya - began with organisms that were designed to live in extremely hot environments, the kinds that wou...