The structure behind the switch
...ail of a kite; when the RNA reaches the end of the stretch of DNA to be transcribed, the entire RNA strand drops away from the DNA and leaves the nucleus. Not so in immunoglobulin production, says Yu. For one thing the part of the DNA that's transcribed during immunoglobulin class switching doesn't actually ...... in Huntington's, the mutation merely makes a long stretch of repeats even longer, without actually altering any particular short sequence. But they did find another difference, a change in a single DNA letter that appears in 70 per cent of defective genes. Adding an siRNA that matches this telltale sequence......erse specialization as a rule, it is not too far a stretch to suggest that vocal-learning mammals, including humans, also evolved diverse specialized glutamate receptor expression in vocal areas of their cerebrums and that these are related in part to vocal syntax complexity." Jarvis received his doctoral de...Marine biologists probe 'black box' mysteries of the sea
... plastic kitchen scrubbers installed along a short stretch of shore. "It turned out to be real patchy for some reason. There were some spots out there that reliably recruited mussels, and others just a few feet away that didn't, so a lot of the variation that's going on is being driven at the small scale rat...Rice University announces nanotechnology research agreement with IBM
... just one-billionth of a meter in diameter but can stretch a millimeter or more in length. That's analogous to a 15-mile-long garden hose. Calculations on the IBM eServer p690 are showing that even small imperfections in the tubes can drastically affect their mechanical and electrical properties. "What happ...Stretch of I-40 part of ORNL, UT environmental lab initiative
...ee major interstate highways converge on a 20-mile stretch through Knoxville. The area of the field lab is also home to three large truck stops, a trucking company terminal and other trucking industry-related facilities. In addition to the two existing meteorological towers, researchers plan to install equip...Once big bad wolf, now man's best friend: Science studies trace dogs' origins
...sts looked specifically at the "control region," a stretch of DNA known to accumulate mutations relatively quickly, making it a good place to look for differences between dogs and wolves. Computer programs grouped certain sequences inherited together, or "haplotypes," according to their similarities. The hap...Envisats ASAR reveals extent of massive oil spill off Spanish coast
...orts indicate that oil has already fouled a 200-km stretch of Spanish coastline. The presence of oil on the sea surface damps down smaller wind generated waves. It is these waves that reflect the radar signal back in the direction of the source. When they are damped, the reflected power measured by the radar...Stanford researchers develop gene therapy technique that sharply cuts risks
... piece of DNA containing the Factor IX gene plus a stretch of DNA that acts as an "insert me" signal to integrase. At the same time they injected a gene for integrase. Within a week, mice that received this injection made 12 times more Factor IX than their littermates that received the injection with...Virginia Tech wildlife sciences professor improves sheep counts in Grand Canyon
...rginia Tech graduate students, survey the 200-mile stretch by land, followed by a helicopter count. This method helps Vaughan figure in any miscalculations or errors in his estimates. "Prior to our research, there had always been strict helicopter restrictions in the Grand Canyon," explains Vaughan. "As a re...Rogue trees get criminal treatment from scientists.
...w underneath a house and cause the subsidence may stretch for several metres in different directions. The scientists have set up a company, Bioprofiles Ltd, to carry out the work. It is believed to be the first company in the UK to offer this service. It will be working for aboriculturalists tree speci...Of mice and men: Deaf mouse leads scientists to new human hearing loss gene
...am's research. Both TMIE and Tmie are located on a stretch of DNA that is similar in humans and mice -- a stretch that has been sequenced by both the mouse and human genome projects. The ready availability of DNA ...Bioengineered, rhythmically beating heart muscle could aid cardiac research
...nvironment, on a flexible substrate. We could then stretch the tissue cells in a certain way to simulate the effects of mechanical loads on tendon, muscle bone, ligament, and cartilage and also add the shear stress that occurs during fluid flow in blood vessels. Dr. Cascio very astutely thought we could grow...Without blue crabs, southern salt marshes wash away, study finds
...ational Academy of Sciences. Southern salt marshes stretch from Chesapeake Bay to the central-Florida coasts. They are some of the most productive grasslands in the world. The marshes also temper coastal flooding, filter mainland run-off and act as nurseries for commercially important fish and other species....Researchers identify defect that causes rare muscular dystrophies
...rotect individual muscle cells from damage as they stretch and contract. They also help hold the cells in place by acting like a molecular Velcro that binds individual cells to the extracellular matrix, providing a bridge critical for the physical integrity of muscle. In the most common form of muscular dyst...MIT's biorubber ushers in new possibilities in tissue engineering
... defining property of a rubberband: the ability to stretch then snap back to an original shape. The dominant material in todays market is hard and brittle. "If you think about it, though, many of the organs in the body are elastic," said Robert Langer, MITs Germeshausen Professor of Chemical and Biomedical E...Researchers find synthetic molecules that may literally be the key to 'locking away' unwanted DNA
...small molecules have also only really been able to stretch across a couple of DNA base pairs. But now Dr. Mike Hannon & Dr. Alison Rodger, research chemists at the University of Warwick, have produced a large synthetic molecule, a Supramolecular Cylinder, which binds to the major groove of DNA, rather than t...NIAID unveils bioterrorism research agenda
... Additional research has been conducted on ways to stretch current smallpox vaccine stockpiles for the short term. Treatments. The increase in antibiotic resistance among bacteria and the relative scarcity of effective antiviral drugs make treatment research imperative. Scientists will use information gai...New test detects colon cancer gene
... of different types and can occur anywhere along a stretch of a thousand or so nucleotides in the gene, making mutations especially difficult to detect in a consistent fashion. The scientists circumvented these problems by perfecting techniques to isolate human DNA from fecal samples and to isolate and ampli......rce probe, or more force, to indent a bone than to stretch a collagen molecule. "The surface can recover bac... pulling the collagen molecule(s) again." For the stretch experiments the group used purified cow tendon, and for the indentation experiments they used collag...