Gene therapy corrects sickle cell disease in mice, Science authors report
... another and link themselves into long fibers that stretch the red blood cell into its characteristic sickle shape. Sickled cells can get stuck in blood vessels and block blood flow, leading to anemia, stroke, and organ damage. Despite the fact that sickle cell was the first genetic disorder for which a mut...World's smallest lizard discovered in Caribbean
...uerto Rico. So small it can curl up on a dime or stretch out on a quarter, a typical adult of the species, whose scientific name is "Sphaerodactylus ariasae," is only about 16 millimeters long, or about three quarters of an inch, from the tip of the snout to the base of the tail. It shares the title of "s...World's smallest lizard discovered in the Caribbean
...onment." So small it can curl up on a dime or stretch out on aquarter, a typical adult of the species Sphaerodactylus ariasaeis only about 16 millimeters long, or about three quarters of aninch, from the tip of the snout to the base of the tail. Itshares the title of "smallest" with another lizard spec...Packard, Stanford researchers uncover gene family critical to asthma development
...ver, when McIntire and her colleagues analyzed the stretch of DNA more closely they found that the development of AHR was actually linked to a nearby group of genes, which they named the Tim family. The researchers are now investigating whether this gene family is also linked to the development of ast...Hidden toxin gene in chlamydia linked to chronic illnesses
...s studied that region in more detail, they found a stretch of DNA that resembled a known gene for the so-called toxin B of Clostridium difficile. That bacterium causes a potentially fatal infection of the large intestine in humans and is closely related to the deadly microbes that cause tetanus, botulism a......e of Technology in Cambridge. "We know that we can stretch the research dollar by having scientists at NIEHS and grantees at universities work in concert," said Kenneth Olden, Ph.D., director of NIEHS. "But perhaps more important, we know that bringing ideas together in science increases the advances we achi...UI researchers and colleagues identify genetic changes in bacterial biofilms
...iotics and once we know that we may be on the home stretch for creating new drugs," Greenberg said....Researchers uncover a piece of nature's secret nitrogen formula
...N2 (two atoms of nitrogen) floating in the air and stretch it, weakening the bond between the two nitrogen at...gen atoms. "We've shown that this type of iron can stretch nitrogen bonds, but now we want to see how this enzyme goes to the next step and breaks that bond," ...... dimer with two identical subunits. These subunits stretch across the cell membrane, coming together at the top (outside of the cell) and opening up like two outstretched arms on the inside of the cell. When the arms encounter lipid A, they close around the polar molecule, flip it over, and send it through t...Experimental drug decreases age-related blood vessel stiffening
...). It also improved the blood vessels' ability to stretch by about 14 percent. Results are to be reported in the Sept. 25 issue of Circulation, an American Heart Association journal, but were posted online Sept. 3. ALT-711 is manufactured by Alteon Inc., Ramsey, N.J. Vascular stiffening and its related i...New study puts dinosaur noses in their place
...e been interested because dinosaurs really seem to stretch the bounds of physiological form," said Witmer, an associate professor of biomedical sciences and anatomist in the university's College of Osteopathic Medicine. "By looking at the noses of dinosaurs and their modern-day relatives, we've potentially b...Using hard science to protect fragile seas
...cific Grove Marine Gardens Fish Refuge - a popular stretch of beach known worldwide for its magnificent tide pools. The state prohibits the taking of marine life from the Pacific Grove refuge, unless one obtains a special permit for scientific gathering. Now a local citizens` group is demanding a complete b...DNA analysis of salamanders turns up new species under almost every log, UC Berkeley zoologists find
...happened to find the same solution - slim down and stretch out - to the problem of burrowing. Apparently, the...er, 14, but grew them longer. Both have tails that stretch nearly twice the length of the rest of the body. Wake and Parra-Olea found from their DNA analysis, ...URI professor investigates the muscle behind blue mussels
...ds are stronger than most rubber materials and can stretch up twice their length before breaking. That funct...s slack are useless. The ability of the threads to stretch allows additional threads to be recruited to hold on. An adult mussel is about 2 inches long. (The t...When Shewanella meets goethite: Evidence found of recognition between animate and inanimate objects
...then pulling your foot away from the pavement. You stretch the biomolecule until it snaps off. By measuring the stretching characteristics, we think we can tell which biomolecule is there. We are literally looking at their nano-mechanical characteristics." Co-investigators on the NSF grant are Lower at ...Key step in gene activation discovered
... the nucleosome spool, liberating the gene on that stretch of DNA so it can unwind far enough to be accessible to another molecule, the "Transcription Enzyme," whose job is to move along the gene's length coping its code. Other molecules then use this copy to make proteins, which do the work specified by th...Researchers study muscle cell damage that occurs when astronauts return from space
...ng down stairs or down a hill, that simultaneously stretch and contract muscles, the result is microscopic tears in the membrane of the muscle cells. Dr. McNeil suspects that the muscle soreness athletes experience is probably a consequence of this tearing; that tearing triggers an inflammatory response d...Coastal research project at UC Santa Cruz receives major boost in funding
...organisms in nearshore habitats along a 1,200-mile stretch of coastal waters from Oregon to southern California. The nearshore zone, from the shoreline out to about six miles off shore, is heavily influenced by human activities, but the natural dynamics of the ecological communities in this zone are not well...First FDA approved, non-drug treatment for high-blood pressure now available
...low breathing stimulates slowly adapting pulmonary stretch receptors in the cells of the lungs, which leads to blood pressure reduction. "This device and its related program encourages compliance with daily breathing exercises that are individually customized to adjust the breathing pattern of each patient t...New method for studying ocean currents to help fight erosion
... The camera filmed a 500-meter stretch of the beach's "surf zone" -- the area where ocean waves break and circulate against the shore. The new software analyzed the image of the water, focusing on the white, foamy pat...