Of mice and men: Deaf mouse leads scientists to new human hearing loss gene
...nts made by Kohrman's team to "search" for similar stretches of DNA in tissue samples from the families, the groups at Iowa and NIH checked for defects in the human TMIE gene. They found three mutations in a day and a half, then found two more -- each causing hearing loss in one of five different families. "Th...Essential cell division 'zipper' anchors to so-called junk DNA
...uences, are liberally represented along those vast stretches of the human genome not known to directly control genetic activity, sometimes referred to as junk DNA. "One thing that interested us is that there are 500 thousand to 1 million Alu repeats across the human genome," says Ramin Shiekhattar, Ph.D., an a...Ghana takes aim at bushmeat hunting
...cated in the heart of the Upper Guinea Forest that stretches across 10 countries from Guinea to northwestern Cameroon. CI has identified this forest as one of the 25 world's critical Biodiversity Hotspots. It is home to 551 mammalian species more than any other Hotspot and some 514 species of birds. In 1957,...Study helps explain gene silencing in the developing embryo
...ed histone proteins could organize the genome into stretches of active and silent regions. Moreover, these regions would be inherited during cell division. The study was supported by grants from the National Institute of General Medicine at NIH and the American Cancer Society....It may take a mouse to understand the behavior of 'jumping genes'
...called "jumping genes." Retrotransposons are small stretches of DNA that are copied from one location in the genome and inserted elsewhere, typically during the genesis of sperm and egg cells. The L1 variety of retrotransposons, in particular, are responsible for about one third of the human genome. The mouse ...The mouse genome and the measure of man
... percent of the mouse genome with long, continuous stretches of DNA sequence and represents a seven-fold covera... than the mouse genome. Repeat sequences are short stretches of DNA that have been hopping around the genome by copying and inserting themselves into new regions...Vast, wild Northern Forest gains new allies: 18 projects named in $1.8 million study
...al reserves in the vast, wild Northern Forest that stretches from Maine through Vermont and New Hampshire to New York's Adirondacks. Another cluster of university researchers will use GIS and satellite mapping to measure and predict the movement of invasive species through the forest's ecosystem. And a third t...Facing extreme ice conditions, coast guard, NSF deploy second icebreaker to Antarctica
...40 miles out. He added that very dense "pack ice" stretches roughly 200 miles from the station to iceberg C-19, which broke away from the Ross Ice Shelf in May. The U.S. Coast Guard vessel Healy, an icebreaker with design features for supporting Polar science, particularly in the Arctic, left its home port o...Young plant's natural defenses amount to more than just its seed
... the most critical a plant will ever make: once it stretches its fragile stem up toward the sky, there's no turning back to the safe haven of the seed. Yet, growing up may not be quite as risky for a young plant as once was believed. According to Rockefeller University research, newborn plants have a second ch...SRS research highlights from the Red-Cockaded Woodpecker Symposium
...ded woodpeckers can still be found in a range that stretches from Virginia to Florida and west to the eastern part of Texas and southeast Oklahoma. Red-cockaded woodpeckers are uniquely adapted to the fire-maintained southern pine ecosystem and require relatively large, living pine trees for nesting. The fourt...Marine biologists probe 'black box' mysteries of the sea
...h hole. When a wave hits the plastic golf ball, it stretches the spring, giving researchers an accurate measurement of the amount of force that struck the shore. "The dynamometers see a lot of force, but it varies from place to place," Denny noted. "For instance, we have one transect with about 100 dynamometer...Oxygen deficiency is an endocrine disruptor in fish
...traviolet light. And because it occurs across vast stretches of water around the world, hypoxia could be a greater concern than any of these. The research is reported in the March 15 print edition of Environmental Science & Technology , a peer-reviewed journal of the American Chemical Society, the world's la...A subtle tool to study mankind's diseases
...erg) developed a new technique to engineer greater stretches of DNA in bacteria. The researchers, now working at the Biotec-Technical University in Dresden, have just used this method to engineer a complex set of changes in a mouse gene, in hopes of shedding light on human leukemias. Their work appears in the ...New technique gives scientists clearest picture yet of all the genes of an animal
...et to actually be confirmed. Plus, there are long stretches of the chromosomes that remain terra incognita that may contain genes yet to be discovered." In their study, Vidal and his colleagues checked the accuracy of the map of the C. elegans genome using a technique of their own design. (Conventional tech...Finished Y-chromosome sequence reveals a genomic 'crystal palace'
... containing genes that impact male fertility, vast stretches of mirror-image DNA, and an assortment of function...encing techniques have been confounded by the long stretches of nearly identical DNA that lack the landmarks needed to guide the assembly of sequences from small...Sequence of human chromosome 7 is fine-tuned and finished
...s about 1,150 genes and 940 so-called pseudogenes, stretches of DNA that closely resemble genes but contain som...ng individuals. Children with WBS are missing long stretches of these duplicated genes. "It seems that multiple copies of these genes are necessary for normal de...Scientists with Hawaii ocean mixing experiment
...ile largely submerged volcanic mountain chain that stretches from the Big Island of Hawaii to Midway Island, due to its rough topography, including large underwater mountains and valleys. Such areas are sometimes referred to as the "stirring rods" of the oceans. Prior to the HOME project, areas such as the Haw...Weather extremes shed light on prairie's past and environment's future
...ar-shaped tall grass area scrutinized in the study stretches from Tulsa, Okla., to Fargo, N.D., to Indianapolis. European explorers entering what they called "an inland sea" found a humid area with grasses up to 6 feet tall. Long before, the plains were bulldozed flat during four major glacial advances and re...Chemical change may help predict seriousness and course of some cancer
...he gene, and the neighboring first exon. Exons are stretches of DNA that contain the information for the protein described by the gene. Genes from the normal breast cells showed low to moderate methylation in the exon and little or no methylation in the promoter. Nearly one-third of breast tumors sampled also...New book says Northwest salmon could face same fate as those in Northeast, England
...ggests removing homes from the flood plain on some stretches of river to allow the stream to meander back and forth, flooding naturally and maintaining salmon habitat. But, he contends, a decision on how to proceed should come from weighing all of the options, not by waiting until there are no options left. ...