Access to DNA secrets yields better understanding of genes, possible tool for disease diagnosis
...ers can detect the relative compactness of several stretches of DNA at a time with very high resolution, allowing them to determine which genes have the propensity for making RNA. They found that for many genes, but not all, the more open the DNA is, the more RNA is produced. "The interesting genes are the on...AGU journal highlights - 29 July 2004
... Andreas Fault A set of deep seismic monitors that stretches for more than 1,200 meters [3,900feet] within the San Andreas Fault can likely provide unique information about thevolatile fault system and allow unprecedented monitoring for earthquakes inSouthern California. Chavarria et al. present vertical seism...DNA variations surprise researchers
...me scanning technologies, we serendipitously found stretches of DNA sometimes hundreds of thousands of chemical bases (nucleotides) long that were present or absent in the genomes of healthy individuals. These large-scale copy variations, or LCVs, frequently overlap with genes and could explain why people are ...Heartless worms hold clues to cardiac arrhythmias, sudden death
...auses, Petersen said, the unc-103 pharynx has long stretches of pauses, "as if the worms are having an arrhythmia." The team developed a method to quantitate the pauses and demonstrated that "knocking out" the unc-103 protein using a technique called RNA interference restored normal pharyngeal pumping. The in...Researchers find clues about how antibodies specialize
...sification through selective mutations to specific stretches of DNA in B cells that encode immunoglobulins, the proteins from which antibodies are made. Mutations in these gene segments to the so-called variable regions -- give our B cells the ability to make unique, specialized antibodies with high affinity ...Trojan Horses, xenon imaging and remote controlled genes
...off. They have created caged antisense molecules stretches of DNA that can clamp on top of working genes that are released when their chemical cage is hit by ultraviolet or infrared light. "By uncaging these molecules, our goal is to alter protein expression within a particular cell and at a particular...Genuine stem cells found in skin might treat hair loss, wounds
... the backs of hairless mice, the cells also formed stretches of skin, tufts of hair, and sebaceous glands, which secrete an oily substance known as sebum that lubricates skin and hair. "We've identified cells within skin that bear all the characteristics of true stem cells--the ability for self renewal and th...Human chromosome 5 final sequence analysis released to public
..., other important genetic motifs gleaned from vast stretches of noncoding sequence have been found on Chromosom...ve powerful regulatory influence." These gene-free stretches were previously considered "junk DNA," but in recent years those seemingly barren regions have taken...