Tag: "striatum" at biology news

Growth Factor Stimulation Leads To Increase In New Neurons In The Striatum And Cortex Of The Brain

NEW ORLEANS -- The number of new neurons in the striatum and cortex, key areasof the brain responsible for ...e brain, but also that the number ofneurons in the striatum and outer brain, or cortex, increased significantly. Contrary to a long-held belief that neu...

Inhibitor Shows Potential To Protect Infant Brain

...e affected hemisphere. The cortex, hippocampus and striatum had shrunk, and the fluid-filled ventricles had ex...ats. And they lost 53 percent less tissue from the striatum and 33 percent less from the cortex, the brains wrinkled top layer. The number of neurons that vanis...

UF researcher: gene therapy effective in animal studies of Parkinson's disease

...t connect them to another part of the brain -- the striatum in the forebrain. In separate experimental grou...ats that received the treatment exclusively in the striatum improved, Mandel said. The effects persisted through the six months of the experiment. "We saw sig...

Progress on the molecular basis of mental illness in children

...difference in dopamine transporter availability in striatum was found between the depressive and the non-depressive children and adolescents. Citation source: Molecular Psychiatry 2000 Volume 5, pages 514-522. For further information on this work, please contact Dr. Minna Dahlstrsm, Clinic of Child Psychiatr...

Manganese exposure may speed the emergence of Parkinson's disease symptoms, according to new findings in animals

...l. Other parts of the basal ganglia, including the striatum and globus pallidus, are the targets of manganese toxicity. "If two areas in the same pathway are weakened, you get an additive impact, and that's what we believe occurred in this experiment," Smith said. In the experiment, rats were treated with a...

Gene therapy restores feeding behavior to starving mice

...he mid-brain that send their axon processes to the striatum played a key role in integrating brain signals to ...behaviors. But they did not know which part of the striatum would be involved. The striatum is divided into two segments -- the caudate putamen and the nucleus ...

Scans link 2 key pieces of schizophrenia puzzle

...sic science findings that dopamine activity in the striatum is under the control of the prefrontal area. Stim...ons that project from the prefrontal cortex to the striatum are inhibitory in effect, suggesting an anatomical mechanism by which reduced prefrontal activity mi...

New food-addiction link found

...first time, that the dopamine system in the dorsal striatum plays a role in food motivation in the human brain. This relationship was not observed in the ventral striatum, which includes the nucleus accumbens, the area of the brain thought to be responsible for food reward. "We and others previously thought t...

Gene enhances prefrontal function at a price

...he gene turns-on more in neurons projecting to the striatum (an area in the middle of the brain) in people who...iant likely triggers more dopamine activity in the striatum indirectly, by dampening prefrontal dopamine activity. A resulting weak prefrontal signal-to-noise ...

Sleep disorders linked to faulty brain chemistry, study finds

... with the fewest dopamine-producing neurons in the striatum of their brains had the worst RBD symptoms of thrashing, talking and violent flailing while they slept. And patients with the lowest levels of acetylcholine-producing neurons in the brainstem had the most interruptions in their breathing during sleep...

Link between neuronal calcium channel, mutated gene that causes Huntington's disease identified

...been clear why in Huntington's only neurons in the striatum are affected," said Dr. Ilya Bezprozvanny, associa...out what the mutant huntingtin gene does to kill striatum neurons and opens potentially new areas for treatment of the disease." Calcium triggers the release ...

Drug addiction, learning share common brain protein

...aine triggers changes in a brain region called the striatum -- a reward center that also plays a fundamental r...increase in communication among nerve cells in the striatum that use dopamine as their chemical messenger. This brain chemical surge is responsible for the feel...

Adolescent brains show reduced reward anticipation

...and dorsal midbrain, with the magnitude of ventral striatum activation sensitive to gain amount. In adolescent...rchers found lower activation of the right ventral striatum centered in the nucleus accumbens, a region at the base of the brain shown by earlier research (see ...

Crucial brain development gene identified

...er birth. Internally, there is an expansion of the striatum region of the brain, along with the formation of abnormal cell groupings called rosettes. Interestingly, the rosette structures seen in Lgl1-mutant brains resemble those seen in human patients with medulloblastoma (a type of brain tumor that arises ...

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