The First Rejection: Eggs Sequester Bits Of Sperm For Later Elimination
...r and Pitnick decided to look more closely at this stubborn section of sperm tail. Using electron microscopy, they determined that it was composed of what is called the mitochondrial derivative a crystallized form of the sperm's mitochondria. Mitochondria are normally inherited only from the mother, and provi...Breakthrough: Scientists Create 3-D Map Of Cell Membrane Ion Pump At Near Atomic Resolution
...rchers used a detergent-likecompound to overcome a stubborn technical difficulty. The problem was thatunlike most other proteins, cell membrane proteins are embedded in a naturalgreasy substance that makes growing crystals of them nearly impossible. By a clever strategy, Scarborough succeeded in getti...Researchers Offer DOD New Hazardous Waste Clean-Up Methods
...ht and dense nonaqueous phase liquids,particularly stubborn contaminants, from beneath the ground. "We feel we accomplished what we set out to do--to select and carefullytest the most promising innovative environmental remediation technologies forclean up of DOD sites," says Carroll L. Oubre, program ...Experimental Staph Vaccine Broadly Protective In Animal Studies
...Staphylococcus aureus (S. aureus), an increasingly stubborn microbeand the most common cause of hospital-acquired infections. The new vaccine isthe first to be made from a bacterial molecule produced primarily duringinfection, rather than in laboratory culture. A report of the study byscientists at Brigham ...Researchers glimpse polio virus as it enters host cell
...mise to eliminate it globallyit has proved to be a stubborn subject for scientists. Surprisingly little is known about how poliovirus enters the cells of the intestines, let alone how it makes its way to the nervous system where it can damage motor neurons and cause paralysis. Some have suspected that after a...Protein that stimulates blood vessel growth also helps repair broken bones
...giogenesis, such as VEGF, might help to heal these stubborn breaks. To test VEGF as a possible treatment, Helms' team worked with 20 mice with broken limbs that were being treated with pain-relieving drugs. After splinting the legs of these mice, the researchers shifted the splint each day to a different ...Chronic Lyme disease symptoms not helped by intensive antibiotic treatment
...lind trials testing antibiotics in patients with a stubborn form of Lyme disease-those whose symptoms persist after standard courses of antibiotics-validate that these patients suffer significant pain and other disabling symptoms. The two trials found, however, that a 90-day course of intravenous and oral a...Scientists using gene chips identify a unique form of leukemia
... or within the first year of life, and have such a stubborn form of disease that only about 40 percent of the infants survive. What stands out about most of these infants at least 70 percent is that their blood cells are the scene of a chromosomal accident. In the majority of cases, portions of their 4th ...Structure of key receptor unlocked; Related proteins will fall like dominoes
After two years of stubborn persistence, scientists at Johns Hopkins have determined the 3-D structure of part of a protein called HER3, which should speed efforts to interfere with abnormal growth and cancer. "It took us more than two years to interpret the data and get HER3's...Natural-born killers enlisted to fight anthrax
...mailrooms or subway stations, in addition to those stubborn few that might remain hidden in people's noses. Old strategy reinvented The idea of using phage to fight bacterial infections is not new. Beginning in the 1930s, Soviet physicians employed whole phage, also referred to as "phage therapy," to trea...Loblolly pine open for genetic engineering, research shows
...d in the genetic engineering of this important but stubborn species," Gould said. Acceptable rates of transformation have been documented in other pines such as Afghan, Virginia and Monterey but not in loblolly, she noted. "There is a broad spectrum of applicability for this technology in the genetic improv...Rice, Brookhaven physicists decode initial stage of cell fusion
...National Laboratory have unraveled one of the most stubborn mysteries of basic biology -- the structure of the initial stage of membrane fusion. Described in this week's issue of Science, the findings open the door for studies that could improve the effectiveness of gene therapy and drug delivery. While we co...Genome analysis sheds light on drug-resistant pathogen
...led the bacterium Enterococcus faecalis to acquire stubborn resistance to a range of antibiotics including a drug of last resort that is used against such bacterial pathogens. That is one of the conclusions reached by scientists at The Institute for Genomic Research (TIGR), which sequenced and analyzed the c...'Crystal engineering' helps scientists solve 3-D protein structures
...s helped solve the structures of some particularly stubborn proteins, including the so-called V antigen of Yersinia pestis, the bacterium that causes the plague. Despite numerous attempts, researchers had been unsuccessful in unlocking the secrets of this protein, which plays a key role in the bacterium's abi...Newborn lambs' central heating system could aid fat busting in humans
...to some kind of diet to move those couple of extra stubborn pounds. But by reactivating natural brown fat we could lose weight without even trying. "Each year between two to three million newborn lambs die of hypothermia at cost of up to 100 million to the industry. Farmers have even tried to put quilted jack......mia. Yet for some patients who harbor particularly stubborn genetic mutations, Gleevec fails miserably. Now, Howard Hughes Medical Institute (HHMI) researchers at the University of California, Los Angeles, and colleagues at Bristol-Myers Squibb Oncology in Princeton, NJ, are reporting the first descrip...