Adaptive changes in the genome may provide insight into the genetics of complex disease
...nt of Genome Sciences at UW,which is a large-scale study of genetic variation and how it may affect thefunction of human genes. Akey performed the research as a postdoctoral research fellow in thelaboratory of Dr. Leonid Kruglyak at the Fred Hutchinson Cancer ResearchCenter's Human Biology Division. The pr...Story tips from the Department of Energy's Oak Ridge National Laboratory, September 2004
... with computer simulation of molecular motions, to study the structural changes in more detail than ever be...ransformation from low to high density forms. This study shows a more complex slow transformation -- a significant finding with general implications for glas...Reducing allergens in the home helps inner-city children with asthma
DALLAS Sept. 9, 2004 A study designed to reduce the levels of indoor allergens ...uchalla, chief of allergy at UT Southwestern and a study author. "We can't just focus on medications. We must also focus on allergen triggers in the home and...New research suggests link between maternal diet and childhood leukemia risk
A new study suggests that eating more vegetables, fruit and pr...onent of the National Institutes of Health. The study was conducted by researchers at the University of California, Berkeley, and the study results are pu...A new protein is discovered to play a key role in cancer progression
...r. Pandolfi and colleagues in a recently published study in the Journal of the National Cancer Institute. ...d activity restores normal cell functions. "The study found an unexpected role of cPML which highlights the importance of analyzing the status of PML in h...Viral suspect for amphibian decline traced to human spread through bait
...hibian populations in the western U.S. The genetic study indicates that the virus may have been transmitted...lion National Science Foundation funded project to study "Emerging Wildlife Diseases: Threats to Amphibian Biodiversity." Under the grant, Collins and his te...Final Alert: 16th EORTC NCI AACR Symposium
... be press-released include: Results from Phase I study of first second-generation antisense cancer drug u...dictive test clears way to targeted treatment New study indicates arsenic could be suitable first-line treatment for a type of leukaemia Prize-winning stud...... a Perspectives article in Science, the key to the study is that Wang and his colleagues took advantage of the fact that the Smac-IAP protein-protein interaction is relatively unstructured, since only the N-terminal amino acids of Smac interact with IAP. "This property allowed them to readily create a lib...Screen siblings, parents of infants with severe heart abnormalities
...of Medicine (BCM) in Houston. In a new study in the September issue of the journal Pediatrics, Drs. Jeffrey Towbin, BCM professor of pediatrics at BCM, and John Belmont, BCM professor of molecular and human genetics, found that these first degree relatives of children with severe defects of the...Pneumococcal vaccine reduces ear infections, pneumonia, new study shows
...dence of middle ear infection and pneumonia, a new study shows. "This highlights that the vaccine signific... Vanderbilt Children's Hospital in Nashville. The study appears in the September issue of the journal "Pediatrics." The pneumococcal conjugate vaccine is w...Fossils reveal direct link between global warming and genetic diversity in wildlife
...y occurs among large populations of animals, "this study shows that gene flow is occurring when population ...not be how it actually persists through time." The study also has implications for wildlife managers in the greater Yellowstone ecosystem who are trying to m...Heart gene yields insights into evolution, disease risk
...r an intellectual model for a broader evolutionary study of genetics. This broader study would aim to bridge the gap between medical scientists' detailed molecular understanding of the gene...Common cold virus can cause polio in mice when injected into muscles
...niche of eradicated polio" he said. Results of the study will be published in the Sept. 6, 2004, issue of t...lled receptors, on host cell surfaces. The current study turned that belief on its head, said Gromeier. Poliomyelitis has long been regarded as the signature...Imitative parrots just might tell you it's all in the tongue
...syrinx operates similarly in all parrots. For this study thescientists used five monk parakeets, small parrots native to SouthAmerica. While a speaker swept through a series of tones, from 500 to11,000 Hz (from the B above a piano's middle C to a high-pitched Fbeyond the keyboard's range), the researchers ...Genetic map of important tree genes outlined
...ling it to respond to environmental stresses. The study also compared many of these gene sequences to thos...d. "Once you know a lot of gene sequences and can study thousands of genes at a time, you can start to really explore how trees might respond on a basic gen...Recent evolution at a single gene may have brought down heart disease risk in some human groups
...o influence heart disease. The genetic trait under study concerns a particular base pair of DNA one of billions in the human genome that helps regulate the gene stromelysin-1, or MMP-3. The identity of the DNA base at this position differs between individuals and influences the rate of production of the ...In a world of distortion, archer fish learn to judge absolute size of aerial prey
...rey from an underwater vantage point. Here, as the study of Schuster and colleagues shows, the complex optical situation arising from distance and refraction requires precise understanding of the relationship between an object's apparent size and the fish's relative position to the object. In the experime...How do you mend a broken heart?
... collective expertise of the group, to develop and study human cells with an enhanced potential for cardiac regeneration. Along with Prof. Rosenthal, Italian researcher Giulio Cossu (San Raffaele Biomedical Park of Rome, Italy) brings extensive experience to the project. He recently discovered a multipoten...Bone marrow cells routinely help with wound healing
...titutes of Health, which supported the work. "This study shows that bone marrow stem cells, in addition to cells from the surrounding tissue, may actually contribute to the healing process. If this is the case, it could lead to completely new ways of treating serious wounds." When a body is wounded, the...As informatics grows, Indiana University helps set 'research agenda'
...eld, it's still very young. But informatics -- the study of information technology and its use -- has already had a palpable effect on people's lives. "In recent decades, technology has so enhanced our ability to gather data that the sheer volume of data now outstrips our capacity to deal with it," said I...