Two Long-sought Diabetes Gene Found
...The findings have also stimulated the search for a substance that could increase the expression of either of these genes. "Many transcription factors respond to other proteins that trigger increased activity," said Bell. "The identification of this biochemical signal could lead to new approaches for treating d...Pinpoint Gene Control Holds Promise For Nervous System Studies
...dult mice the genefor nerve growth factor (NGF), a substance that has beendifficult for scientists to study because it's so difficult tomanipulate. Investigators believe the method will make possibleimportant studies into the way our nervous system works. "Thistechnology gives us an unprecedented opportun...CSIRO Discovery Fights Cell Ageing
CSIRO scientists have discovered a natural substance which rejuvenatesageing human skin cells. Dr Robi...hown that Beta Alistine' (b alany l histidi ne) a substance naturally present in human andanimal tissues, has remarkable properties when it comes to fighting th...Vitamin C Deficit Linked To Skin Disease
...cks for the production of heme, an iron-containing substance found in allbody tissues. In people with PCT, a critical enzyme in the liver becomesinactivated, interfering with the production of heme from its precursorporphyrins. As a result, the porphyrins build up in the liver, spill into theblood and are car...Early Menarche Puts Young Girls In Peril
...t much higher risk than boys for eating disorders, substance abuse, dropping out of school, depression and suicide," Brumberg says. Brumberg warns: "Contemporary girls are in trouble . . . young women develop physically earlier than ever before, but within a society that does not protect or nurture them in wa...NIH Office Of Dietary Supplements Expands Research Support
...nthesis in the intestinal tract. Glutathione is a substance that may have a protective effect against dietary and bacterial toxins found in infants whose intestinal function may be impaired by disease. In addition to these three new projects, the ODS will continue its support of five studies begun in 1996, ...Scientists Find New Trigger For Nerve Cell Death
...rotective effect wasseen even in the presence of a substance that prevents calcium from flowing intocells. "These experiments don't rule out a role for calcium in apoptosis," Yusays. "But they do suggest that potassium outflow is independently an importantmechanism." Moreover, the potassium c...Common Food Dye Can Cause Severe Allergic Reactions
...eople can avoid allergic reactions is to avoid the substance they're allergic to---but that's often impossible ...in the skin of a person who is not allergic to the substance being tested. P-K tests are rarely administered anymore because of concern over blood-borne infecti...Free Radicals Implicated In Impaired Lung Function; Damage May Be Mitigated By Certain Antioxidants
...iscule increase above an acceptable threshold of a substance in the blood that indicates cell damage caused by bombardment from free oxygen molecules (a condition defined as oxidative stress) reflects damage to the lungs equivalent to the effect of 3-5 years of aging, or of approximately 15-20 pack years of s...Regulator Of Fat Thermostat Found
...human leptin concentrations.And surprisingly, this substance also boosted leptin levels in some overweightindividuals. In the study conducted by endocrinologist Samuel Dagogo-Jack, M.D., assistantprofessor of medicine, and by John W. Newcomer, M.D., assistant professor ofpsychiatry and of psychology, oral ad...Mystery Of Vital Cell Protein Solved After 30 Years
... up intensely in recent years whentaxol, a natural substance found in the bark of the Pacific yew tree (the name"taxol" has been trademarked by Bristol-Myers-Squibb), was shown in clinicaltests to be an effective treatment for a number of cancers including ovarian,breast, and lung. Cancer occurs when cell div......, and a gene for green fluorescent protein(GFP), a substance found normally in fluorescent jellyfish but now used bymolecular biologists to mark genetically altered cells, into a disabledadenovirus -- the same virus that causes colds. The modified adenovirus was inturn introduced into rat olfactory neurons. ...Garlic Prevents Hardening Of Aorta, New Study Shows
...he garlic may causethe endothelium to secrete some substance to dilate the vessels and makethe aorta more elastic,” he said. This research was funded by the pharmaceutical company Lichtwer PharmaGmbH, a manufacturer of standardized garlic tablets in Berlin, Germany....... This gland, found above the hind legs,secretes a substance that functions as an antibiotic and prevents bacteriaand fungi from invading the ants' nests and infecting the members of thecolony. The development of this gland is believed to be associated withthe evolution of the ants' social system, which has b......ommendation for testing does not necessarilymean a substance is a carcinogen or mutagen butoften reflects -- as...ntial oils; Myristicin, a naturally occurring substance in such spices as black pepper, anise, nutmeg and mace and in carrots and parsley; 2-Chloropyr...Low Cholesterol? Reduced Sodium? What Do These Terms Really Mean?
...asked thesubject to report how much of the dietary substance noted in the label waspresent in one serving of the soup (bottom of Figure 1). On the answer sheet,the U.S. Recommended Daily Values for each dietary component, based on a 2,000calorie per day diet, were listed as a reference (from USFDA, 1995). Pro...At Life's Most Sensitive Stage, Embryos Cope With Stress
...organisms often defendagainst toxins by taking the substance into their cells and transforming it,"Epel said. During embryogenesis, contact with such toxins could damage DNA,proteins or cell membranes, and thus interfere with the embryo's development. Sothe innkeeper worm1s embryo detects toxins as soon as the...PEBBLEs Help U-M Scientists Open A Window On Cell Chemistry
...th of light. As the concentration of the targeted substance changes, the intensity of the PEBBLE's fluorescence increases or decreases. Once the PEBBLEs are ready, Clark uses pico-injection techniques or a gene gun to fire them randomly into human or mouse cells in a culture dish. "The PEBBLEs blast thr...... been connectedto interleukin-1 (IL-1), a cellular substance thought to cause the painfulinflammation and debilitating erosion in rheumatoid joints. After January 1996FDA approval, researchers injected cells genetically engineered to block theaction of IL-1 directly into selected RA patients' joints. This ge...